Rchr
J-GLOBAL ID:200901089732732712
Update date: Sep. 11, 2024
Fujimoto Nariaki
フジモト ナリアキ | Fujimoto Nariaki
Affiliation and department:
Research field (3):
Environmental effects of chemicals
, Environmental effects of radiation
, Urology
Research keywords (7):
Biological effects of exposure to radioactive particles
, Thyroid tumor; childhood irradiation; animal models
, thyroid hormone; hypothalamus-pituitary-thyroid axis; rat models
, Estrogen
, EDCs
, Pituitary
, androgen; rat prostate; mouse prostate; prostate cancer
Research theme for competitive and other funds (29):
- 2024 - 2026 Mechanisms of long-term gene expression changes in the rat thyroid by neonatal irradiation - a possible mechanism related to thyroid carcinogenesis by childhood radiation
- 2024 - 2025 Effects of internal exposure to radioactive 31-silicon dioxide particles - Biological effects, mechanisms of action and risk evaluation
- 2020 - 2023 小児期放射線被曝による甲状腺機能への影響と障害メカニズムの解明
- 2019 - 2023 Biological effects of radioactive MnO2 particles
- 2019 - 2023 Radiation exposure and health effects of the residents around the former Soviet Union nuclear test site in Kazakhstan -A new perspective: radioactive microparticles-
- 2016 - 2019 Influence of chemicals used in consumer products on endocrine-system via activation of nuclear receptors
- 2018 - 2019 Effects of internal exposure to radioactive 56-manganese dioxide particles - Biological outcomes, mechanisms of action and risk evaluation
- 2014 - 2018 Study of the radiation fallout around the former Soviet Union Semipalatinsk nuclear test site - Dosimetry and health effects -
- 2013 - 2015 Estimation of target proteins of hydroxylated PCB and brominated flame retardants for thyroid hormone disruption and the influence by radiation
- 2011 - 2013 Risk assessment of chemicals using chimeric mice with humanized liver
- 2011 - 2013 Quantitative analysis of neonatal exposure to thyroid hormone disrupting chemicals
- 2010 - 2012 Determination of targets for thyroid hormone disruption by brominated flame retardants
- 2009 - 2011 Clarification of the genes involved in the hyperlipidemia and the application to the preventive medicine
- 2008 - 2010 Effects of neonatal exposure to thyroid hormone disrupting chemicals in rats
- 2007 - 2009 Evaluation of adverse effects of chemicals in the 'sensitive population'
- 2007 - 2009 Risk evaluation of chemical-induced hepatic hyperplasia
- 2006 - 2007 Formation of Hydroxylated Metabolites Responsible for the Toxicity of Brominated Flame Retardants and Thyroid Hormone Disrupting Action
- 2005 - 2006 Effects of low-dose endocrine disruptors on neonatal prostatic development
- 2004 - 2006 Studies of risk assessments of pre-and post-natal exposure to endocrine-disrupting chemicals
- 2004 - 2005 Thyroid hormone-disrupting activity of brominated retardants and hydroxylated PCBs
- 2002 - 2003 エストロゲン受容体プロモーター遺伝子導入/改変動物による内分泌攪乱物質作用の解析
- 2001 - 2003 Biological effects of EDCs (Endocrine Disrupting Chemicals)
- 2001 - 2002 Metabolic activation of endocrine-disruptors in animal body
- 2001 - 2002 Effect of Dioxin and Endocrine disrupters on Adrenal Hormone
- 2001 - 2001 ラット前立腺モデルによる内分泌攪乱物質のエストロゲン受容体発現への作用解析
- 1998 - 2000 Mechanisms of Endocrine Disrupting Chemicals
- 1998 - 1999 Mechanisms of hormone dependent growth of cancer : A pituitary model
- 1996 - 1998 Construction of mouse embryonic stem cells for the detection of gene mutation
- 1996 - 1997 Genetic alteration in gastric metaplasia
Show all
Papers (138):
-
Stepanenko, Valeriy, Shinkarev, Sergey, Kaprin, Andrey, Apsalikov, Kazbek, Ivanov, Sergey, Shegay, Peter, Ostroumova, Evgenia, Kesminiene, Ausrele, Lipikhina, Alexandra, Bogacheva, Viktoria, et al. Comparison of external dose estimates using different retrospective dosimetry methods in the settlements located near Semipalatinsk Nuclear Test Site, Republic of Kazakhstan. JOURNAL OF RADIATION RESEARCH. 2024. 65. 1. 36-46
-
Abishev, Zhaslan, Ruslanova, Bakhyt, Apbassova, Saulesh, Shabdarbayeva, Dariya, Chaizhunussova, Nailya, Dyusupov, Altai, Azhimkhanov, Almas, Zhumadilov, Kassym, Stepanenko, Valeriy, Ivanov, Sergey, et al. Effects of radioactive 56MnO2 particle inhalation on mouse lungs: A comparison between C57BL and BALB/c. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023. 24. 24
-
Inoue K, Kawano N, Fujimoto N, Takeichi N, Hoshi M. The need for measures to prevent radiation exposure in Ukraine, taking both internal and external exposure into account. J Environ Radioact. 2023. 107238. 266-267
-
Abishev Z, Ruslanova B, Apbassova S, Chaizhunussova N, Shabdarbayeva D, Azimkhanov A, Zhumadilov K, Stepanenko V, Ivanov S, Shegay P, Hoshi M, Fujimoto N. Effects of internal exposure of radioactive 56MnO2 particles on the lung in C57BL mice. Curr Issues Mol Biol. 2023. 45. 3208-3218
-
Valeriy Stepanenko, Andrey Kaprin, Sergey Ivanov, Peter Shegay, Viktoria Bogacheva, Hitoshi Sato, Kazuko Shichijo, Shin Toyoda, Noriyuki Kawano, Megu Ohtaki, et al. Microdistribution of internal radiation dose in biological tissues exposed to 56Mn dioxide microparticles. Journal of radiation research. 2022. 63. Supplement_1. i21-i25
more...
MISC (22):
-
藤本 成明, 松山 睦美, 中島 正洋. ラット新生仔期甲状腺への放射線被曝で誘発される甲状腺機能不全. 日本内分泌学会雑誌. 2019. 95. 1. 449-449
-
藤本 成明, 松山 睦美, 中島 正洋. 新生仔期での甲状腺被曝で特異的に誘発される甲状腺病変. 日本毒性病理学会講演要旨集. 2019. 35回. 54-54
-
佐能正剛, 中村直樹, 鈴木賢一, 柏木啓子, 花田秀樹, 山本卓, 新海正, 杉原数美, 藤本成明, 北村繁幸, et al. 環境化学物質におけるカエル甲状腺ホルモン作用のアゴニストおよびアンタゴニスト活性. 衛生薬学・環境トキシコロジー講演要旨集. 2014. 2014. 189
-
藤本成明, 中村直樹, 佐能正剛, 太田茂, 浦丸直人, 北村繁幸, 宮川信一, 井口泰泉. 新生仔ラットへの水酸化PBDE投与の影響. 環境ホルモン学会研究発表会プログラム・要旨集. 2014. 17th
-
藤本成明, 中村直樹, 佐能正剛, 太田茂, 浦丸直人, 北村繁幸, 宮川信一, 井口泰泉. 新生仔ラットの甲状腺ホルモン応答遺伝子発現への臭素化難燃剤の影響. 環境ホルモン学会研究発表会プログラム・要旨集. 2013. 16th
more...
Lectures and oral presentations (18):
-
Gene expression changes in the spleen, the lung, and the liver of rats exposed to 31SiO2 particles
(The 25th Hiroshima International Symposium "Research on radiation and its effects in Kazakhstan and other countries" 2024)
-
The pulmonary and hepatic gene expression changes in mice exposed to radioactive particles of 56MnO2,
(The 8th International Conference on Advances in Biochemistry and Molecular Biology 2023)
-
Radiation health effects of radioactive particles produced by atomic bombing - Studies in laboratory rats and mice at SMU
(XVI International Scientific and Practical Conference <Ecology-Radiation-Health> 2023)
-
Single neonatal irradiation induces long-term morphological and gene expression changes in the thyroid of rats - a possible mechanism of thyroid carcinogenesis by childhood radiation
(Modern Perspectives for Biomedical Sciences 2022)
-
Gene expression alternation by neonatal irradiation in rats II
(The 94th annual congress of the Japan Endocrine Society 2022)
more...
Education (2):
- 1988 - 1992 Hiroshima University Graduate School, Division of Medical Sciences Pathlogy
- 1978 - 1982 Hiroshima University Faculty of Science
Professional career (1):
- Ph.D. (Hiroshima University)
Committee career (3):
- 2018/04 - 2026/03 Food Safety Commission of Japan, Cabinet Office, Government of Japan Commission member / Food Safety Commission of Japan
- 2016/04 - 2018/03 Food Safety Commission of Japan, Cabinet Office Expert advisor / Food Safety Commission of Japan
- 2005/04 - 2016/03 Food Safety Commission of Japan, Cabinet Office commission member / Food Safety Commission of Japan
Awards (4):
- 2023/07/21 - Ministry of Health of the Republic of Kazakhstan Professor Emiritus of Semey Medical University
- 2022/05/26 - Semey Medical University, Kazakhstan Cooperative Research Award of Semey Medical University
- 2013 - Best Poster Award, ISPROF 2013
- 2003 - Best Paper Award 2003 in Journal of Health Science
Association Membership(s) (5):
The Japan Society of Endocrine Disrupters Research
, Japanese Society of Toxicologic Pathology
, Japan Hormonal Steroid Society
, The European Society of Endocrinology
, The Japan Endocrine Society
Return to Previous Page