Rchr
J-GLOBAL ID：200901089957122034
Update date: Feb. 24, 2025
MURAKAMI Tatsuya
ムラカミ タツヤ | MURAKAMI Tatsuya
Affiliation and department：
Job title：
Professor
Other affiliations (1)：
-
京都大学
高等研究院 物質-細胞統合システム拠点
客員教授
Homepage URL (2)：
http://www.pu-toyama.ac.jp/BR/murakami/index.html
,
http://www.moleng.kyoto-u.ac.jp/~moleng_05/index.html
Research field (4)：
Applied biofunctional and bioprocess engineering
, Clinical pharmacy
, Nanobioscience
, Biomaterials
Research keywords (6)：
Lipoprotein
, Eye drop
, Age-related macular degeneration
, Photodynamic therapy
, Biological Chemistry
, Drug Delivery System
Research theme for competitive and other funds (25)：
- 2024 - 2025 Development of drug delivery system targeted to neovessels in the posterior eye segment
- 2020 - 2025 Optical control of the plasma membrane functions by using dynamic exciton
- 2020 - 2025 Dynamic Exciton: Emerging Science and Innovation
- 2023 - 2024 Biomaterials for prevention/treatment of eyefrail
- 2021 - 2024 治療用ナノ粒子の創製:リポタンパク質の構造と機能に着目した眼難治疾患治療戦略
- 2023 - 2024 Photodynamic therapy for age-related macular degeneration using peptide-solid lipid nanoparticles
- 2022 - 2024 Development of peptide eye drops for treatment of age-related macular degeneration
- 2018 - 2021 Eye drop administration of recombinant serum lipoproteins for the treatment of age-related macular degeneration
- 2018 - 2020 Safe and quick control of cell structure/function by using subcellularly localized nano-heaters
- 2017 - 2020 Development of Nano-Bio Interface for Safe Phototherapy and Optical Manipulation of Cell Function
- 2015 - 2018 Development of optical control method of cell organelle function by photoindeuced charge separation molecule
- 2013 - 2018 Quest for Fundamental Principles in Photoinduced Charge Separation and Their Application
- 2016 - 2017 The development of novel treatment of age-related macular degeneration using high-density lipoprotein
- 2015 - 2017 膜親和性ナノ材料による脂質二重膜構造の光制御とその医療応用
- 2013 - 2017 自己組織化による光機能発現
- 2013 - 2017 Creation of novel drug nanoparticles based on the conventional reverse molecular design using poor water-soluble compounds and the efficacy evaluation
- 2014 - 2016 Potential therapy with artificial HDL and photoresponsive nanomaterial for Age-related maculopathy
- 2013 - 2016 'Deep-etch' electron microscopic analysis of the actual mechanism of entry of cell-penetrating nanoparticles used for drug and gene-delivery into living cells
- 2013 - 2016 光応答性ナノ材料による脂質二重膜構造変換とその医療応用
- 2012 - 2016 Cell Nanoengineering: Control of Cell Functions by External Stimuli-Responsive Nanomaterials Delivered to Specific Organelle
- 2012 - 2014 Manipulation of high-density lipoprotein structure and function for development of gene delivery carrier
- 2007 - 2010 生体ナノ粒子を模倣した医療用金属ナノ粒子の創製
- 2007 - 2009 Development of metastatic breast cancer therapies with anticancer drug-loaded inorganic nanoparticles targeted to lymph nodes
- 2006 - 2008 ナノテクノロジーを用いた薬剤投与システムの開発による消化器癌の新しい治療戦略
- 2003 - 2007 ナノテクノロジーを利用した新しいドラッグデリバリーシステムの開発
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Papers (89)：
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Tatsuya Murakami, Haruka Kurita. The distinct properties of high-density lipoprotein nanoparticles as ocular drug delivery vehicles. Nanomedicine. 2025
-
Hayato Takagi, Çetin Çelik, Ryosuke Fukuda, Qi Guo, Tomohiro Higashino, Hiroshi Imahori, Yoko Yamakoshi, Tatsuya Murakami. Interaction of a pyrene derivative with cationic [60]fullerene in phospholipid membranes and its effects on photodynamic actions. Beilstein Journal of Organic Chemistry. 2024
-
Tatsuya Murakami. (Invited) Drug Delivery System of Photoresponsive Donor-Acceptor-Linked Molecules to Mouse Retina. ECS Meeting Abstracts. 2024
-
Koji Takata, Shiori Shibukawa, Chika Morimoto, Shingi Hashioka, Tatsuya Murakami. Microvortex-induced turbulent mixing for reconstitution of high-density lipoprotein-mimicking nanoparticles with aggregation-prone phosphatidylcholine. Lab on a Chip. 2024. 24. 13. 3276-3283
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Ryosuke Fukuda, Rumina Shima, Shiori Shibukawa, Tatsuya Murakami. Comprehensive Analysis of Drug Loading into Engineered Lipoprotein Nanoparticles toward Their Eye Drop Application. ACS Applied Bio Materials. 2024. 7. 1. 99-103
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MISC (58)：
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河上亮, 福田亮介, 須田謙史, 中野絵梨, 市岡愛, 辻川明孝, 村上達也, 村上達也. Neovasculature-targeted lipoprotein mutant eye drops for the treatment of wet age-related macular degeneration in mice. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
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澁川しおり, 槻尾優衣, 福田亮介, 村上達也, 村上達也. Corneal Epithelial Cell Affinity and Posterior Eye Drug Delivery Ability of Lipoprotein Variants. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
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河上亮, 福田亮介, 河西文武, 小倉正恒, 村上達也, 村上達也. アクティブターゲティング能を付与した治療用ナノ粒子の作製と生物活性評価. 日本DDS学会学術集会プログラム予稿集. 2021. 37th
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福田亮介, 福田亮介, 福田亮介, 福田亮介, MAHMUDA Nargis, 河上亮, 長井良憲, 中野絵梨, 須田謙史, 辻川明孝, et al. CD13リガンドと細胞膜透過ペプチドを含む人工HDL点眼剤の可能性. 日本DDS学会学術集会プログラム予稿集. 2021. 37th
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島瑠美奈, 福田亮介, 澁川しおり, 水上侑, 河上亮, 河西文武, 河西文武, HUWYLER Jorg, 村上達也, 村上達也, et al. ゼブラフィッシュによるリポタンパク質の体内動態評価. 日本DDS学会学術集会プログラム予稿集. 2021. 37th
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Patents (11)：
Books (3)：
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DDS with peptide self-assemlies
2023 ISBN:9784861049361
-
Whole Aspect of Phase Separation in Biology
2020 ISBN:9784807913466
-
機能性DDSキャリアの製剤設計
シーエムシー出版 2008
Lectures and oral presentations (14)：
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環拡張ポルフィリン結合リポ蛋白質による持続的光線温熱効果と磁気共鳴イメージング
(第36回日本バイオマテリアル学会 2014)
-
カーボンナノチューブの光線力学効果
(第30回日本DDS学会学術集会 2014)
-
リン脂質ナノディスクと光応答性ナノ材料の生物医学応用
(日本動物実験代替法学会第26回大会 2013)
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カーボンナノチューブの光線力学効果と殺細胞活性
(第29回日本DDS学会学出集会 2013)
-
生体由来ナノディスクの機能改変と生物医学応用
(第7回ナノ・バイオメディカル学会大会 2013)
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Education (2)：
- - 1998 Kyoto University
- - 1993 Osaka University School of Engineering
Professional career (1)：
Work history (7)：
- 2016/04 - 現在 Kyoto University Institute for Integrated Cell-Material Sciences Visiting Professor
- 2016/04 - 現在 Toyama Prefectural University Faculty of Engineering Department of Pharmaceutical Engineering Professor
- 2009/01 - 2016/03 Kyoto University Institute for Integrated Cell-Material Sciences Program-specific associate professor
- 2008/10 - 2012/03 Japan Science and Technology Agency PRESTO
- 2005/06 - 2008/12 Fujita Health University Institute for Comprehensive Medical Science Assistant Professor
- 2003/04 - 2005/05 Japanese Foundation for Cancer Research Cancer Institute Postdoctoral fellow
- 1998/04 - 2003/03 Kyowa Hakko Kirin Co., Ltd.
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