Research field (2):
Morphology, anatomy
, Laboratory animal science
Research keywords (4):
腎臓
, 疾患モデル
, 実験動物学
, 腎疾患
Research theme for competitive and other funds (13):
2024 - 2027 メサンギウム細胞特異的Creマウスの創出による糸球体疾患進行機序の解明
2019 - 2024 ゴルジ体ストレスシグナルに着目した新たな老年病発症メカニズムの解析
2020 - 2023 脳老化に関わる小胞体選択的オートファジー基質の探索と神経老化制御への応用
2014 - 2017 アルツハイマー病に対する生体恒常性維持機構の解明と糖尿病によるその破綻
2014 - 2016 腎疾患高感受性C57BL/6マウス系統の開発
2013 - 2016 創薬・疾患研究のための細胞・組織コレクション供給体制確立に関する研究
2011 - 2014 The development of novel and useful mouse models for kidney diseases
2011 - 2014 糖尿病とアルツハイマー病の相互病態修飾におけるインスリン・シグナルの役割
2010 - 2013 実験動物を用いた周産期疾患の解析と繁殖技術の開発
2010 - 2013 血管から見たアルツハイマー病の新規治療法の開発
2009 - 2011 Analysis of molecular link between Alzheimer' s disease and diabetes mellitus
2007 - 2010 動物資源の安定供給に向けた繁殖および品質管理技術の高度化に関する研究
2007 - 2010 細胞研究資源の資源化ならびに品質評価法・特性解析法開発に関する研究
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Papers (58):
Kozue Uchio-Yamada, Keiko Yasuda, Kentaro Oh-hashi, Noboru Manabe. Abnormal glomerular basement membrane maturation impairs mesangial cell differentiation during murine postnatal nephrogenesis. American Journal of Physiology-Renal Physiology. 2022. 324. 1. F124-F134
Suzuki O, Koura M, Uchio-Yamada K, Sasaki M. Urinary protein analysis in mice lacking major urinary proteins. Experimental Animals. 2021. 70. 3. 406-411
Kozue Uchio-Yamada, Keiko Yasuda, Yoko Monobe, Ken-ichi Akagi, Osamu Suzuki, Noboru Manabe. Tensin2 is important for podocyte-glomerular basement membrane interaction and integrity of the glomerular filtration barrier. American Journal of Physiology-Renal Physiology. 2020. 318. 6. F1520-F1530
Osamu SUZUKI, Minako KOURA, Kozue UCHIO-YAMADA, Mitsuho SASAKI. Analysis of the transgene insertion pattern in a transgenic mouse strain using long-read sequencing. Experimental Animals. 2020. in press
Uchio-Yamada K, Tanaka M, Manabe N. C1r/C1s deficiency is insufficient to induce murine systemic lupus erythematosus. Genes and Immunity. 2019. 20. 2. 121-130
O. Suzuki, M. Koura, K. Uchio-Yamada, M. Sasaki. Search of capacitation-related surface proteins in mouse sperm by differential fluorescent two-dimension electrophoresis. MOLECULAR BIOLOGY OF THE CELL. 2016. 27
O. Suzuki, M. Koura, Y. Noguchi, K. Uchio-Yamada, J. Matsuda. REDUCED SUPEROVULATION EFFICIENCY BY HIGH-DOSE TREATMENT OF DEHYDROEPIANDROSTERONE IN MICE. REPRODUCTION FERTILITY AND DEVELOPMENT. 2013. 25. 1. 307-307
O. Suzuki, M. Koura, Y. Noguchi, K. Uchio-Yamada, J. Matsuda. Analysis of the hr Gene in a Hairless Mouse Strain (HR). JOURNAL OF THE AMERICAN ASSOCIATION FOR LABORATORY ANIMAL SCIENCE. 2012. 51. 5. 702-703
Osamu Suzuki, Minako Koura, Yoko Noguchi, Kozue Uchio-Yamada, Junichiro Matsuda. Altered neddylation in the heart of a mouse model for cardiomyopathy. FASEB JOURNAL. 2012. 26
O. Suzuki, M. Koura, Y. Noguchi, K. Uchio-Yamada, J. Matsuda. EFFECTS OF DEHYDROEPIANDROSTERONE ON SPERM FERTILIZABILITY IN VITRO AND TESTICULAR GENE EXPRESSION. REPRODUCTION FERTILITY AND DEVELOPMENT. 2012. 24. 1. 201-202
2003/04 - 2003/09 Kyoto Prefectural University of Medicine
Committee career (1):
2024/03 - 現在 関西実験動物研究会 評議員
Association Membership(s) (5):
日本畜産学会
, SOCIETY FOR REPRODUCTION AND DEVELOPMENT
, JAPANESE SOCIETY OF NEPHROLOGY
, JAPANESE ASSOCIATION FOR LABORATORY ANIMAL SCIENCE
, THE JAPANESE SOCIETY OF VETERINARY SCIENCE