Toume Kazufumi

トウメカズフミ | Toume Kazufumi

Affiliation and department：
Job title： Assistant Professor
Homepage URL (2)： http://www.inm.u-toyama.ac.jp/pharmacognosy/index-j.html , http://www.inm.u-toyama.ac.jp/pharmacognosy/index-e.html

Research field (1)： Environmental and pharmaceutical development resources

Research theme for competitive and other funds (17)：

2022 - 2025 Recovery from refractory anxiety by reconstruction of neuronal networks
2021 - 2024 Metabolomic profiling of Wakan-yaku for quality evaluation
2021 - 2022 Development of high value-added Rhubarb effective for neurological disorders
2018 - 2022 Development of refined profiling analysis for multiple components in crude drugs and Kampo formula
2018 - 2021 Comprehensive study on diversity of Curcuma drugs used as medicines / food supplements for standardization, responding to a global society

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Papers (91)：

Shunsuke Shimizu, Aoi Nakano, Daisuke Ihara, Hironori Nakayama, Michiko Jo, Kazufumi Toume, Katsuko Komatsu, Naotoshi Shibahara, Masaaki Tsuda, Mamoru Fukuchi, et al. Panax notoginseng root extract induces nuclear translocation of CRTC1 and Bdnf mRNA expression in cortical neurons. Drug discoveries & therapeutics. 2024
Shunsuke Shimizu, Aoi Nakano, Daisuke Ihara, Hironori Nakayama, Michiko Jo, Kazufumi Toume, Katsuko Komatsu, Naotoshi Shibahara, Masaaki Tsuda, Mamoru Fukuchi, et al. Panax notoginseng root extract induces nuclear translocation of CRTC1 and <i>Bdnf</i> mRNA expression in cortical neurons. Drug Discoveries & Therapeutics. 2024
Hironori Nakayama, Daisuke Ihara, Mamoru Fukuchi, Kazufumi Toume, Chisato Yuri, Masaaki Tsuda, Naotoshi Shibahara, Akiko Tabuchi. The extract based on the Kampo formula daikenchuto (Da Jian Zhong Tang) induces Bdnf expression and has neurotrophic effects in cultured cortical neurons. Journal of Natural Medicines. 2023. 77. 3. 584-595
Yuki Tayama, Shusaku Mizukami, Kazufumi Toume, Katsuko Komatsu, Tetsuo Yanagi, Takeshi Nara, Paul Tieu, Nguyen Tien Huy, Shinjiro Hamano, Kenji Hirayama. Anti-Trypanosoma cruzi activity of Coptis rhizome extract and its constituents. Tropical medicine and health. 2023. 51. 1. 12-12
Qundong Liu, Katsuko Komatsu, Kazufumi Toume, Shu Zhu, Ken Tanaka, Shigeki Hayashi, Naoko Anjiki, Nobuo Kawahara, Akihito Takano, Katsunori Miyake, et al. Essential oil composition of Curcuma species and drugs from Asia analyzed by headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry. Journal of natural medicines. 2022

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MISC (96)：

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Patents (10)：

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Lectures and oral presentations (3)：

マイクログリアM2化活性に着目した長野県産大黄の品質評価
(日本薬学会年会要旨集 2022)
モンゴルのSaposhnikovia divaricataの根に含まれる代謝産物の特性分析と定量(Characterization and quantification of metabolites in Saposhnikovia divaricata roots from Mongolia)
(和漢医薬学会学術大会要旨集 2020)
モンゴル産防風のクロモン類の含量と地域的特徴(Determination of characteristic chromones in Saposhnikoviae Radix from Mongolia based on regional attributes)
(日本薬学会年会要旨集 2020)

Education (3)：

2002 - 2005 Chiba University Graduate School of Medical and Pharmaceutical Sciences
- 2002 Chiba University
- 2000 Chiba University Faculty of Pharmaceutical Sciences

Work history (2)：

2014/09 - 現在 University of Toyama Institute of Natural Medicine Associate Professor
2009/06 - 2014/09 Chiba University Graduate School of Pharmaceutical Sciences Assistant Professor

Awards (1)：

2014/09 - 一般社団法人日本生薬学会学術奨励賞シグナル伝達に作用する生物活性天然物の探索研究

Association Membership(s) (3)：

MEDICAL AND PHARMACEUTICAL SOCIETY FOR WAKAN-YAKU , 日本生薬学会 , 日本薬学会

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