Rchr
J-GLOBAL ID：200901090767891285   Update date: Nov. 15, 2024

Hachisu Masakazu

ハチス マサカズ | Hachisu Masakazu
Affiliation and department：
National Institute of Technology,Tsuruoka College Department of Creative Engineering

About National Institute of Technology,Tsuruoka College Department of Creative Engineering


Job title： Associate Professor
Homepage URL  (2)： https://www.tsuruoka-nct.ac.jp/gakka/souzou/cb/ ,  https://www.tsuruoka-nct.ac.jp/en/faculty/department-of-chemical-and-biological-engineering/
Research field  (3)： Bioorganic chemistry ,  Applied biochemistry ,  Polymer materials
Research keywords  (6)： Immunoregulatory molecule ,  Biopolymer ,  Glycoconjugate ,  Carbohydrate ,  Amino acid ,  Lipid
Research theme for competitive and other funds  (3)：
  • 2023 - 2026 Regulation of mast cell activation and immune tolerance by food-related factors focusing on short-chain fatty acid
  • 2021 - 2024 スルファチド類縁体の構造活性相関研究:新規作用機序インフルエンザ薬創製の基盤構築
  • 2015 - 2017 Systematic chemical synthesis and structure-function analysis of glycosylated collagens
Papers (37)：
  • Seidai Takasawa, Kosuke Kimura, Masato Miyanaga, Takuya Uemura, Masakazu Hachisu, Shinichi Miyagawa, Abdelaziz Ramadan, Satoru Sukegawa, Masaki Kobayashi, Seisuke Kimura, et al. The powerful potential of amino acid menthyl esters for anti-inflammatory and anti-obesity therapies. Immunology. 2024. 173. 1. 76-92
  • Yosuke Nakamura, Ngoc-Hung Nguyen, Tomoya Yoshinari, Masakazu Hachisu, Phuong-Thao Nguyen, Kiminori Shimizu. Identification of the oosporeidentification of the oosporein biosynthesis gene cluster in an entomopathogenic fungus Blackwellomyces cardinalis. Mycoscience. 2024. 65. 2. 96-104
  • Kazuki Nagata, Daisuke Ando, Tsubasa Ashikari, Kandai Ito, Ryosuke Miura, Izumi Fujigaki, Yuki Goto, Miki Ando, Naoto Ito, Hibiki Kawazoe, et al. Butyrate, Valerate, and Niacin Ameliorate Anaphylaxis by Suppressing IgE-Dependent Mast Cell Activation: Roles of GPR109A, PGE2, and Epigenetic Regulation. The Journal of Immunology. 2024. 212. 5. 771-784
  • Genki Mori, Sarira Rahimian, Rika Ozawa, Kenya Murata, Masakazu Hachisu, Gen-ichiro Arimura. Development of Menthyl Esters of Valine for Pest Control in Tomato and Lettuce Crops. Plants. 2024. 13. 7. 1015
  • Miki Ando, Kazuki Nagata, Ryuki Takeshita, Naoto Ito, Sakura Noguchi, Natsuki Minamikawa, Naoki Kodama, Asuka Yamamoto, Takuya Yashiro, Masakazu Hachisu, et al. The Gut Lactic Acid Bacteria Metabolite, 10-oxo-cis-6,trans-11-octadecadienoic Acid, Suppresses Inflammatory Bowel Disease in Mice by Modulating the NRF2 Pathway and GPCR-signaling. Frontiers in Immunology. 2024. 15. 1374425-1374425
ｍore...
MISC (14)：
  • 平野敦春, 八須匡和, NGUYEN Ngoc Hung, NGUYEN Phuong Thao, 小竹ひとみ, 西山千春, 清水公徳. Growth of Basidiomycete Yeast Isolated from Parmotrema Tinctorum Is Inhibited by Extracts of Parmotrema Tinctorum. Lichenology. 2023. 21. 2. 62
  • 西山千春, 岡田光, 兒玉直輝, 安藤実希, 伊藤直人, 長田和樹, 八須匡和. The anti-inflammatory effects of a rose flavor compound β-damascone. Aroma Research. 2023. 24. 1. 53-55
  • 西山千春, 芦刈翼, 安藤大介, 飯塚雄輝, 長田和樹, 笠倉和巳, 八須匡和. The effects of salicylaldehyde on IgE-mediated activation of mast cells in vivo and in vitro. Aroma Research. 2023. 24. 1. 17-19
  • 永田彩奈, 平野敦春, 八須匡和, NGUYEN Ngoc Hung, NGUYEN Phuong Thao, 西山千春, 清水公徳. Search for Antifungal Substances Produced by Parmotrema Tinctorum. Lichenology. 2022. 20. 2. 63
  • 平野敦春, 八須匡和, NGUYEN Ngoc Hung, NGUYEN Phuong Thao, 小竹ひとみ, 西山千春, 清水公徳. Growth of Basidiomycete Yeast Isolated from Cladonia Rei Is Inhibited by Extracts of Parmotrema Tinctorum. Lichenology. 2022. 20. 2. 63
ｍore...
Patents (4)：
Books (1)：
  • 相分離生物学の全貌(現代化学増刊46), 白木賢太郎 編
    東京化学同人 2020 ISBN:9784807913466
Lectures and oral presentations  (121)：
  • NR4A3欠損マウスでは樹状細胞上のTLR8発現が亢進し乾癬が悪化する
    (日本農芸化学会2023年度大会 2023)
  • 樹状細胞における短鎖脂肪酸を介したインテグリン遺伝子転写活性化の分子機構
    (日本農芸化学会2023年度大会 2023)
  • 多価不飽和脂肪酸腸内乳酸菌代謝産物γKetoCはNRF3経路を介して炎症性腸疾患を緩和する
    (日本農芸化学会2023年度大会 2023)
  • 短鎖脂肪酸とニコチン酸はGPR109A-PGE2-EP4経路を介してIgE依存性マスト細胞活性化を抑制する
    (日本農芸化学会2023年度大会 2023)
  • Amino Acid Menthyl Esters Exhibit Superior Anti-inflammatory and Anti-obesity Therapies
    (日本分子生物学会年会プログラム・要旨集(Web) 2023)
ｍore...
Education (3)：
  • 2004 - 2008 Hokkaido University Graduate School of Science Division of Biological Sciences
  • 2002 - 2004 Shinshu University Graduate School of Engineering Department of Functional Polymer Science
  • 1998 - 2002 Shinshu University Faculty of Textile Science and Technology Functional Polymer Science Course
Professional career (3)：
  • Doctor of Philosophy (Hokkaido University)
  • Master of Engineering (Shinshu University)
  • Bachelor of Engineering (Shinshu University)
Work history (6)：
  • 2023/04 - 現在 National Institute of Technology,Tsuruoka College Department of Creative Engineering
  • 2021/04 - 2023/03 Tokyo University of Science Faculty of Advanced Engineering, Department of Biological Science and Technology
  • 2015/04 - 2021/03 Tokyo University of Science Faculty of Industrial Science and Technology, Department of Biological Science and Technology
  • 2010/04 - 2015/03 ERATO, The Japan Science and Technology Agency (JST) Ito Glycotrilogy Project
  • 2009/04 - 2010/03 National Institute of Advanced Industrial Science and Technology (AIST) Research Institute of Genome-based Biofactory
Show all
Committee career (1)：
  • 2011/04 - 2019/03 グライコサイエンス若手の会 世話人
Awards (1)：
  • 2016/11 - GlycoTOKYO Encouraging Prize Chemical approaches to probe the mechanism of
Association Membership(s) (6)：
Japanese Association for Food Immunology ,  Japan Society for Bioscience, Biotechnology, and Agrochemistry ,  The Chemical Society of Japan ,  Forum: Carbohydrates Coming of Age ,  The Japanese Society of Carbohydrate Research ,  The Society of Polymer Science, Japan
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