Research keywords (6)：
Bioinorganic chemistry
, Bioorganic chemistry
, Reactive oxygen species
, Arsenic
, Trace element
, Selenium
Research theme for competitive and other funds (15)：
2022 - 2025 Elucidation of biosynthetic pathway of selenosugars
2021 - 2024 Toxicological significance of metal biogenic nanoparticles
2018 - 2021 Molecular mechanisms underlying the formation of bioorganometallic bond for metal toxicology
2017 - 2020 Synthesis and biological evaluation of selenoneine, naturally occurring selenium containing compound
2016 - 2019 Speciation and toxicological study of antimony in the environmental water in eastern and mid-southern China
2015 - 2018 Elucidation of the metabolism and toxicity mechanism of arsenolipids by analytical chemistry techniques
2014 - 2017 Metallome analysis with cellular differentiation
2014 - 2017 Development of novel caged compound bearing off/on switch of light sensitivity
2014 - 2016 Development of dual-modality SPECT/fluorescent probe
2011 - 2013 Development of SPECT probe for oxidative stress imaging
2010 - 2011 生体内redox stateの可視化のためのSPECTプローブの開発と応用
2007 - 2009 Mechanisms underlying circulation of selenium in Biosphere
2007 - 2008 Mechanism of intracellular reactive oxygen species generation by exposure of trivalent arsenic compounds
2004 - 2007 Metallomics of bio-trace elements : Copper, selenium and arsenic
2005 - 2006 ヒ素による酸化ストレス誘導機構のメタロミクスに基づく解明
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Papers (85)：
Yu-Ki Tanaka, Ayuka Takata, Karin Takahashi, Yoshikazu Yamagishi, Yasunori Fukumoto, Noriyuki Suzuki, Yasumitsu Ogra. Thiopurine S-methyltransferase- and indolethylamine N-methyltransferase-mediated formation of methylated tellurium compounds from tellurite. Archives of toxicology. 2024
Hiroaki Fujita, Yu-ki Tanaka, Noriyuki Suzuki, Sota Kuno, Yasumitsu Ogra, Kazuhiro Iwai. PRDX6 augments selenium utilization to limit iron toxicity and ferroptosis. Nature structural & molecular biology. 2024
Yu-ki Tanaka, Hiroki Yanagi, Ayako Shiokawa, Akihiro Matsunaga, Mari Shimura, Satoshi Matsuyama, Yasunori Fukumoto, Noriyuki Suzuki, Yasumitsu Ogra. Role of sulfane sulfur species in elemental tellurium nanorod formation in mammalian cells. Redox Biochemistry and Chemistry. 2024. 8. 100029-100029
Yasunori Fukumoto, Noriyuki Suzuki, Reina Hara, Yu-ki Tanaka, Yasumitsu Ogra. Development of a biosafety level 1 cellular assay for identifying small-molecule antivirals targeting the main protease of SARS-CoV-2: evaluation of in vivo activity of GC376, boceprevir, carmofur, ebselen, and selenoneine. International Journal of Molecular Sciences. 2024. 25. 11. 5767
Yasunori Fukumoto, Rin Kyono, Yuka Shibukawa, Yu-ki Tanaka, Noriyuki Suzuki, Yasumitsu Ogra. Differential molecular mechanisms of substrate recognition by selenium methyltransferases, INMT and TPMT, in selenium detoxification and excretion. Journal of Biological Chemistry. 2024. 300. 2. 105599-105599
2024/04 - 現在 Toho University Faculty of Pharmaceutical Sciences Faculty of Pharmaceutical Sciences Professor
Committee career (6)：
2022/04 - 現在 日本薬学会 環境・衛生部会 衛生試験法注解 用語専門委員会 委員
2022/04 - 現在 日本薬学会 環境・衛生部会 衛生試験法注解 出版委員会 委員
2022/04 - 現在 日本薬学会 環境・衛生部会 衛生試験法注解 編集委員会 委員
2018/04 - 現在 日本毒性学会 生体金属部会幹事
2016/04 - 現在 独立行政法人医薬品医療機器総合機構 医薬品名称委員会 専門委員
2017/04 - 2019/03 日本学術振興会 科学研究費委員会専門委員
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Awards (2)：
2022/09 - 日本微量元素学会 研究学術賞 ケミストリーに基づいた生体微量元素研究の展開
2018/11 - The Japanese Society of Toxicology research encouragement award
Association Membership(s) (5)：
The Pharmaceutical Society of Japan
, Japanese Society for Molecular Imaging
, Japanese Society for Chemical Biology
, Japan Society for Biomedical Research on Trace Elements
, The Japanese Society of Toxicology
