Rchr
J-GLOBAL ID:200901091840112202
Update date: Feb. 01, 2024
Tsubouchi Asako
ツボウチ アサコ | Tsubouchi Asako
Affiliation and department:
Job title:
Head of Drug Discovery
Research field (3):
Pharmaceuticals - chemistry and drug development
, Cell biology
, Neuroscience - general
Research keywords (11):
confocal microscopy
, image analysis
, high throughput screening
, flow cytometry
, gene screening
, drug screening
, Cell Biology
, behavioral analysis
, Neural network
, Sensory Neuron
, Drosophila
Research theme for competitive and other funds (4):
- 2018 - 2020 尿細管細胞や血管内皮細胞における流れ刺激受容チャネルを介する細胞応答機構の解明
- 2014 - 2016 Anatomical and behavioral analysis of adult somatosensory neurons in Drosophila
- 2006 - 2008 樹状突起パターンの多様性を生み出す細胞膜供給機構と新規分子の機能解析
- 2002 - 2003 パキシリンのチロシンリン酸化による細胞運動極性制御機構の解析
Papers (16):
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Kazuhiro Shiizaki, Asako Tsubouchi, Yutaka Miura, Kinya Seo, Takahiro Kuchimaru, Hirosaka Hayashi, Yoshitaka Iwazu, Marina Miura, Batpurev Battulga, Nobuhiko Ohno, et al. Calcium phosphate microcrystals in the renal tubular fluid accelerate chronic kidney disease progression. Journal of Clinical Investigation. 2021. 131. 16
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Rina Kunishige, Mai Mizoguchi, Asako Tsubouchi, Kenjiro Hanaoka, Yutaka Miura, Hiroshi Kurosu, Yasuteru Urano, Makoto Kuro-o, Masayuki Murata. Calciprotein particle-induced cytotoxicity via lysosomal dysfunction and altered cholesterol distribution in renal epithelial HK-2 cells. Scientific Reports. 2020. 10. 1. 20125-20125
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Walcott KCE, Mauthner SE, Tsubouchi A, Robertson J, Tracey WD. The Drosophila Small Conductance Calcium-Activated Potassium Channel Negatively Regulates Nociception. Cell Reports. 2018. 24. 12. 3125-3132
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Asako Tsubouchi, Tomoko Yano, Takeshi K. Yokoyama, Chloe Murtin, Hideo Otsuna, Kei Ito. Topological and modality-specific representation of somatosensory information in the fly brain. SCIENCE. 2017. 358. 6363. 615-622
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Taiichi Tsuyama, Asako Tsubouchi, Tadao Usui, Hiromi Imamura, Tadashi Uemura. Mitochondrial dysfunction induces dendritic loss via eIF2 alpha phosphorylation. JOURNAL OF CELL BIOLOGY. 2017. 216. 3. 815-834
more...
MISC (7):
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A. Tsubouchi, D. Satoh, T. Tsuyama, D. Sato, T. Aigaki, T. Uemura. Shaping diverse morphologies of dendritic arbors of the neurons: distinct dependency on organelle dynamics. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE. 2008. 26. 8. 831-831
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Tadashi Uemura, Daisuke Satoh, Taiichi Tsuyama, Toshiro Aigaki, Asako Tsubouchi. Shaping diverse morphologies of dendritic arbors of neurons: Distinct dependency on organelle dynamics. NEUROSCIENCE RESEARCH. 2008. 61. S14-S14
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坪内 朝子, 坂倉 純子, 八木 良平, 真崎 雄一, Schaefer Erik, 矢野 元, 佐邊 壽孝. 細胞外マトリックス系による細胞増殖と機能の制御 運動中の細胞における,パキシリンのチロシン31及び118のリン酸化により制御されるRhoA活性抑制の局在化機構. 日本発生生物学会大会講演要旨集. 2002. 35回. 98-98
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矢野 元, 坪内 朝子, 佐邊 壽孝. マトリックス分子シグナルの多様性と細胞接着 細胞運動制御おけるチロシンリン酸化の役割. 日本細胞生物学会大会講演要旨集. 2001. 54回. 37-37
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S Hashimoto, A Tsubouchi, Y Mazaki, H Sabe. Interaction of paxillin with p21-activated kinase (PAK). MOLECULAR BIOLOGY OF THE CELL. 2000. 11. 172A-173A
more...
Books (1):
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細胞運動のダイナミクスと癌 インテグリンからのチロシンリン酸化シグナルを介するRhoファミリーの協調的制御機構
実験医学 羊土社 2003
Education (2):
- 1999 - 2004 Kyoto University Department of Biostudies
- 1995 - 1999 Osaka University
Professional career (1):
- Bioscience (Kyoto University)
Work history (6):
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