Rchr
J-GLOBAL ID：200901092277435217   Update date: Jan. 30, 2024

Nishiyama Toshio

ニシヤマ トシオ | Nishiyama Toshio
Affiliation and department：
Tokyo University of Agriculture and Technology Faculty of Agriculture Scleroprotein and Leather Research Institute

About Tokyo University of Agriculture and Technology Faculty of Agriculture Scleroprotein and Leather Research Institute


Job title： Counselor Researcher
Research field  (2)： Applied molecular and cellular biology ,  Functional biochemistry
Research keywords  (22)： 培養皮膚モデル ,  毛髪 ,  真皮 ,  表皮 ,  皮膚 ,  線維芽細胞 ,  表皮角化細胞 ,  基底膜 ,  ラミニン ,  コラーゲン ,  細胞外マトリックス ,  skin equivalent. ,  hair ,  dermis ,  epidermis ,  skin ,  finroblast ,  keratinocyte ,  basement membrane ,  laminin ,  collagen ,  extracellular matrix
Research theme for competitive and other funds  (5)：
  • 2010 - 2012 Generating artificial parenchymal and hollow organs fabricated with collagen fibrils,various cells, and cytokines using a bioreactor that we have developed
  • 2009 - 2011 Characterization and utilization of follistatin family proteins.
  • 2007 - 2009 Generating transplantable artificial tissues composed of collagen fibrils and cells using a newly designed bioreactor
  • 2007 - 2008 Effect of GSK 3 inhibitor on cell function and structural formation in human skin equivalent model
  • 2004 - 2006 Establishment of human skin organotypic cultures (skin-equivalents) as suitable bioassay models and investigation of dermal-epidermal interactions by using the culture system
Papers (13)：
  • Yuko Matsuura-Hachiya, Koji Y. Arai, Taichi Muraguchi, Tasuku Sasaki, Toshio Nishiyama. Type IV collagen aggregates promote keratinocyte proliferation and formation of epidermal layer in human skin equivalents. Experimental Dermatology. 2018. 27. 5. 443-448
  • Koji Y. Arai, Takuya Hara, Toyofumi Nagatsuka, Chikako Kudo, Sho Tsuchiya, Yoshihiro Nomura, Toshio Nishiyama. Postnatal changes and sexual dimorphism in collagen expression in mouse skin. PLOS ONE. 2017. 12. 5
  • Kuniko Kadoya, Satoshi Amano, Toshio Nishiyama, Shinji Inomata, Makoto Tsunenaga, Norio Kumagai, Kyoichi Matsuzaki. Changes in fibrillin-1 expression, elastin expression and skin surface texture at sites of cultured epithelial autograft transplantation onto wounds from burn scar excision. INTERNATIONAL WOUND JOURNAL. 2016. 13. 5. 780-786
  • Kuniko Kadoya, Satoshi Amano, Toshio Nishiyama, Shinji Inomata, Makoto Tsunenaga, Norio Kumagai, Kyoichi Matsuzaki. Changes in the expression of epidermal differentiation markers at sites where cultured epithelial autografts were transplanted onto wounds from burn scar excision. INTERNATIONAL WOUND JOURNAL. 2016. 13. 3. 412-417
  • Yuko Matsuura-Hachiya, Yuji Nakai, Keiko Abe, Toshio Nishiyama, Koji Y. Arai. Recovery of extracellular matrix components by enalapril maleate during the repair process of ultraviolet B-induced wrinkles in mouse skin. Biochemistry and Biophysics Reports. 2015. 4. 180-186
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MISC (143)：
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Books (10)：
  • 老化・老年病研究のための動物実験ガイドブック(日本基礎老化学会編):皮膚老化モデルマウス
    アドスリー 2008
  • 生物薬科学実験講座 「細胞の増殖と成長因子II:マトリックス分子」
    廣川書店 2005
  • 細胞外マトリックス-基礎と臨床-(小出輝、林利彦編):第4章、コラーゲンスーパーファミリータンパク質
    2000
  • 分子生物学研究のための新培養細胞実験法(黒木登志夫、許南浩編):第6章 細胞社会:細胞-マトリックス三次元培養
    1999
  • 細胞外マトリックス研究法(畑隆一郎編):型別コラーゲンの精製・同定(6)XII型、XIV型コラーゲン
    1998
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Lectures and oral presentations  (29)：
  • IV型コラーゲン会合体は培養人工皮膚の表皮基底細胞増殖を促進する
    (第43回日本結合組織学会、第58回マトリックス研究会合同学術集会 2010)
  • IL-1 beta stimulates activin betaA mRNA expression in human skin fibroblasts through MAP kinase pathways, NF-kB pathway and prostaglandin E2.
    (Yokosuka Science Festa 2009 (8th Pan-Pacific Connective Tissue Societies Symposium, 41st Annual Meeting of the Japanese Society of Connective Tissue Research, and 56th Annual Meeting of the Japan Matrix Club) 2009)
  • Effects of reconstituted type IV collagen aggregates on epidermal structure and function in human skin equivalents
    (The 34th Annual Meeting of the Japanese Society for Investigative Dermatology 2009)
  • パルス電気刺激が培養ヒト皮膚細胞に及ぼす影響
    (第82回日本生化学会大会 2009)
  • 再構成IV型コラーゲン会合体が三次元培養皮膚モデルの構造と機能に及ぼす影響
    (第82回日本生化学会大会 2009)
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Works (2)：
  • IV型コラーゲンを導入した新規皮膚モデルの構築
    2009 - 2010
  • IV型コラーゲンを導入した新規皮膚モデルの構築
    2009 - 2009
Education (4)：
  • - 1975 Waseda University Graduate School of Science and Engineering
  • - 1975 Waseda University
  • - 1973 Waseda University School of Science and Engineering
  • - 1973 Waseda University Faculty of Science and Engineering
Professional career (2)：
  • Master of Engineering (Waseda University)
  • Doctor of Science (The University of Tokyo)
Work history (19)：
  • 2016/04 - 現在 Tokyo University of Agriculture and Technology
  • 2003/10 - 2016/03 東京農工大学農学部 教授
  • 2003/10 - 2016/03 Professor, Tokyo University of Agriculture and Technology
  • 2001 - 2003 :(株)資生堂リサーチセンター 皮膚科学研究所 所長
  • 2001 - 2003 :Principal Scientist, Skin Biology Laboratories, Shiseido Research Center
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Committee career (13)：
  • 2003 - 2007 日本結合組織学会 編集委員
  • 2003 - 2007 The Japanese Society for Connective Tissue Research Editorial Board
  • 2004 - 2006 日本化粧品技術者会 学術諮問委員
  • 2000 - 2004 日本研究皮膚科学会 理事
  • 2000 - 2004 The Japanese Society for Investigative Dermatology Board of Director
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Awards (3)：
  • 2002 - 中国化粧品学術討論会 壱等賞
  • 2000 - 国際化粧品化学者連盟学術大会 最優秀賞
  • 2000 - The IFSCC Research Award
Association Membership(s) (15)：
アメリカ研究皮膚科学会 ,  日本生化学会 ,  日本化粧品技術者会 ,  国際化粧品技術者会 ,  日本香粧品科学会 ,  日本マトリックス研究会 ,  日本結合組織学会 ,  日本研究皮膚科学会 ,  The Society for Investigative Dermatology ,  The Japanese Biochemical Society ,  The International Federation of Societies of Cosmetic Chemists ,  Japanese Cosmetic Science Society ,  Japan Matrix Club ,  The Japanese Society for Connective Tissue Research ,  The Japanese Society for Investigative Dermatology
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