Research theme for competitive and other funds (29)：
2023 - 2026 Development and clinical application of a non-invasive drug sensitivity assessment method for ex situ conservation of threatened avian species
2020 - 2023 Novel screening system expressing human metabolic enzymes in vivo
2019 - 2022 Elucidation of vitamin D actions using genetically modified rats and application of vitamin D analogs to medical drugs
2018 - 2021 食品中機能性成分における抱合・脱抱合過程を介した機能発現機構の解明
2017 - 2020 Authenticity of premium honeys by multi-component analysis to prevent food disguise
2017 - 2019 Elucidation of Vitamin D Metabolism and Mechanism of Action using Genetically Modified Rats
2016 - 2019 Construction of evaluation system for vitamin D analogs using genetically modified rats with genome editing
2015 - 2019 Elucidation of electron transfer pathway in cyanobacterial cells and production of novel cyanobacterial cells which degrade aromatic compounds
2016 - 2018 Development of highly sensitive detection system for active form of vitamin D
2014 - 2017 The high-level usage of metabolites of dietary compounds for elucidating the molecular mechanism of functional foods
2013 - 2017 Molecular mechanism of the sphingolipid-like mycotoxin production in the pathogenic fungi
2013 - 2016 Advanced use of vitamin D hydroxylases
2011 - 2013 Whole cell-dependent production of polyphenol conjugates using genetically engineered budding yeast
2010 - 2012 Mechanism of substrate recognition by cytochrome p450s and application to in silico prediction system of metabolites of drug candidates
2009 - 2012 Improvement and development of novel photosynthetic microorganisms which degradate aromatic pollutants in oligotrophic environment
2009 - 2011 Protein Engineering of vitamin D hydroxylases and design of their inhibitors based on their tertiary structure
2008 - 2010 Construction of evaluation system of metabolism for dietary compounds using human xenobiotic enzymes
2006 - 2007 Analysis of regluration mechanism of protein protein interaction in xenobiotic system
1997 - 2000 Stable Co-expression System of Drug Metabolizing Enzymes System, containing both oxidative enzyme and conjugated enzymes.
1995 - 1997 The regluretion of Glucuronosyltransferase Gene Complex
1995 - 1995 肝小胞体グルクロン酸抱合化における糖ヌクレオチドの膜透過反応の再構成
1992 - 1994 Gene structure and reglutation of UDP-glucuronosylytranferase
Molecular mechanisms of glucuronidation in xenobiotics
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Papers (149)：
Seita Chudan, Takuto Kurakawa, Miyu Nishikawa, Yoshinori Nagai, Yoshiaki Tabuchi, Shinichi Ikushiro, Yukihiro Furusawa. Beneficial Effects of Dietary Fiber in Young Barley Leaf on Gut Microbiota and Immunity in Mice. Molecules (Basel, Switzerland). 2024. 29. 8
Rikito Mitsuzane, Reiko Okubo, Miyu Nishikawa, Shinichi Ikushiro, Shintaro Munemasa, Yoshiyuki Murata, Yoshimasa Nakamura, Toshiyuki Nakamura. Enhancing effect of the coexisting alpha-tocopherol on quercetin absorption and metabolism. Free radical research. 2024. 1-16
Rie Mukai, Hitomi Okuyama, Miku Uchimura, Kozue Sakao, Miyu Matsuhiro, Mayumi Ikeda-Imafuku, Yu Ishima, Miyu Nishikawa, Shinichi Ikushiro, Akihiro Tai. The binding selectivity of quercetin and its structure-related polyphenols to human serum albumin using a fluorescent dye cocktail for multiplex drug-site mapping. Bioorganic Chemistry. 2024. 107184-107184
Yuichiro Iwai, Ayano Iijima, Satoko Kise, Chika Nagao, Yuto Senda, Kana Yabu, Hiroki Mano, Miyu Nishikawa, Shinichi Ikushiro, Kaori Yasuda, et al. Characterization of Rickets Type II Model Rats to Reveal Functions of Vitamin D and Vitamin D Receptor. Biomolecules. 2023. 13. 11
Cytochrome P-450 : Cytochrome P-450-linked electron transport system in monooxygenase reaction
Koudansha Scientific Press 1993
Education (4)：
- 1992 Hiroshima University
- 1992 Hiroshima University Graduate School, Division of Biophere Sciences
- 1987 Hiroshima University School of Integrated Arts and Sciences
- 1987 Hiroshima University Faculty of General Science
Professional career (1)：
(BLANK) (Hiroshima University)
Work history (5)：
2017/04 - 現在 Toyama Prefectural University
2007/04 - 2017/03 Toyama Prefectural University
2005/04 - 2007/03 Toyama Prefectural University Faculty of Engineering, Biotechnology Research Center
2004/04 - 2005/03 University of Hyogo of Life Science, Graduate School
1992/04 - 2004/03 Himeji Institute of Technology
Committee career (6)：
2018/04 - 現在 日本フードファクター学会 理事
2016/04 - 2018/03 日本農芸化学会 日本農芸化学会中部支部幹事
2016/04 - 2018/03 日本薬物動態学会 日本薬物動態学会代議員
2013/04 - 2018/03 日本ビタミン学会 日本ビタミン学会代議員
2015/04 - 2017/03 日本生化学会 日本生化学会北陸支部幹事
2006/04 - 2008/03 日本生化学会 日本生化学会北陸支部幹事
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Association Membership(s) (9)：
日本フードファクター学会
, THE JAPANESE SOCIETY OF TOXICOLOGY
, American Chemical Society
, 国際薬物動態学会
, 日本農芸化学会
, ビタミン学会
, 日本薬物動態学会
, 日本生化学会
, International Society for the Study of Xenobiotics
