Research field (3):
Fetal medicine/Pediatrics
, Pharmaceuticals - chemistry and drug development
, Functional biochemistry
Research keywords (3):
細胞分化
, 細胞周期
, 小児がん
Research theme for competitive and other funds (4):
小児固形腫癌の分子生物学的解析及び細胞内情報伝達路の解折
ラパマイシンによる増殖制御遺伝子の転写後発現調節の機構
Molecalan biology and signal transduction of pediatric tamor cells
Study on Posttranscriptional Control of G1 cell cycle Progression through m TOR Pathway
MISC (4):
Hosoi H, Dilling MB, Shikata T, Liu LN, Shu Lili, Ashmun RA, Germain GS, Abraham RT, Houghton PJ. Kinetics of rapamycin-induced p53-independent apoptosis in human rhabdomyosarcoma cells. Cancer Research. 1999. 59. 886-894
Hosoi H, Dilling MB, Liu LN, Danks MK, Shikata T, Sekulic A, Abraham RT, Lawrence Jr RT, Houghton PJ. Studies on the mechanism of resistence to rapamycin in human cancer cells. Molecular Pharmacology. 1998. 54. 815-824
Inhibition of induction of c-mye by IGF-I at a translational level only in maliguaut cells growth inhibited by rapamycin. Proc. Am. Assoc. Cancer Res. 1997. 38. 142