Research keywords (7)：
Gametocyte
, 電子顕微鏡
, Malaria
, Parasitology (including Medical Zoology)
, マラリア
, 寄生虫学
, 寄生虫
Research theme for competitive and other funds (15)：
2023 - 2026 Identification of novel P. falciparum placenta ligands responsible for pregnancy-associated malaria
2022 - 2025 熱帯熱マラリア原虫生殖母体期の感染赤血球における細胞接着機構の解析
2019 - 2024 三日熱マラリア伝搬阻止効果のある患者血漿を用いた新規ワクチン候補抗原の探索
2020 - 2023 Development of novel transmission blocking vaccine targeting microgamete surface antigen of Plasmodium falciparum
2016 - 2019 Analysis of parasitophorous vacuole membrane protein in hemoglobin transport and metabolism of malarial parasites
2015 - 2016 熱帯熱マラリア原虫のヘモグロビン取込み機構の解析
2013 - 2015 Analysis of hemoglobin transport in Plasmodium falciparum
2009 - 2011 A study of the effect of a recombinant immunosuppressive factor from parasites and immune-inhibitory mechanisms
2009 - 2010 ネズミマラリア原虫モデルを用いた寄生胞膜分子の動態解析
2009 - 2010 Analysis of menbrane dynamics and identification of target signal to parasitophorous vacuole menbrane of malaria parasite.
2007 - 2008 Functional analysis of an immunosuppressive factor secreted from a parasite and its application to rheumatoid arthritis model
2006 - 2007 Comprehensive screening and identification of the novel malaria transmission-blocking vaccine candidate antigens
2005 - 2006 病原微生物が発現する宿主細胞認識分子のハイスループットな同定法の開発
2004 - 2006 High-throughput screening of novel malaria vaccine candidates using human immune sera
2001 - 2002 Expression of erythrocyte binding protein in Plasmodium falciparum merozoites isolated from endemic area
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Papers (34)：
Ayaka Omoda, Konomi Matsumoto, Ken-ichi Yoshino, Mayumi Tachibana, Takafumi Tsuboi, Motomi Torii, Tomoko Ishino, Hideyuki Iriko. Skeleton binding protein 1 localizes to the Maurer's cleft and interacts with PfHSP70-1 and PfHSP70-x in Plasmodium falciparum gametocyte-infected erythrocytes. Parasitology International. 2024. 100. 102864-102864
Mayumi Tachibana, Minami Baba, Hideyuki Iriko, Naoaki Shinzawa, Motomi Torii, Tomoko Ishino. Identification of a novel protein localized to the crystalloid of the plasmodium ookinete. Parasitology international. 2024. 102892-102892
Daisuke Ito, Yoko Kondo, Eizo Takashima, Hideyuki Iriko, Amporn Thongkukiatkul, Motomi Torii, Hitoshi Otsuki. Roles of the RON3 C-terminal fragment in erythrocyte invasion and blood-stage parasite proliferation in Plasmodium falciparum. Frontiers in Cellular and Infection Microbiology. 2023. 13
Hitoshi OtsukiOsamu KanekoDaisuke ItoYoko KondoHideyuki IrikoTomoko IshinoMayumi TachibanaTakafumi, TsuboiMotomi Torii. Cysteine Residues in Region 6 of the Plasmodium yoelii Erythrocyte-Binding-like Ligand That Are Related to Its Localization and the Course of Infection. Biomolecules. 2023. 13. 3. 458
Mayumi Tachibana, Hideyuki Iriko, Minami Baba, Motomi Torii, Tomoko Ishino. PSOP1, putative secreted ookinete protein 1, is localized to the micronemes of Plasmodium yoelii and P. berghei ookinetes. Parasitology international. 2021. 84. 102407-102407
Mayumi Tachibana, Hideyuki Iriko, Olga Muratova, Guanhong Song, Yimin Wu, Jetsumon Sattabongkot, Satoru Takeo, Hitoshi Otsuki, Motomi Torii, Takafumi Tsuboi. IMMUNIZATION WITH N-TERMINAL REGION OF A GAMETOCYTE PROTEIN PFS230 SUCCESSFULLY INDUCE TRANSMISSION-BLOCKING ANTIBODIES AGAINST PLASMODIUM FALCIPARUM. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2009. 81. 5. 160-160
