Nonaka Takashi

ノナカタカシ | Nonaka Takashi

Affiliation and department：
Job title： Senior Research Scientist
Homepage URL (1)： http://www.igakuken.or.jp/

Research field (1)： Medical biochemistry

Research keywords (11)： TDP-43 , αシヌクレイン , タウ , パーキンソン病 , アルツハイマー病 , 神経変性疾患 , α-synuclein , tau , Parkinson's disease , Alzheimer's disease , Neurodegenerative disease

Research theme for competitive and other funds (2)：

2002 - The accumulation mechanism of αsynuclein and tau in neuronal cells
αシヌクレイン、タウ、TDP-43の細胞内蓄積機構に関する研究

Papers (102)：

Diana Arseni, Takashi Nonaka, Max H Jacobsen, Alexey G Murzin, Laura Cracco, Sew Y Peak-Chew, Holly J Garringer, Ito Kawakami, Hisaomi Suzuki, Misumoto Onaya, et al. Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP type C. Nature. 2024. 634. 8034. 662-668
大谷麗子, 鴻江真維, 河上緒, 吉田眞理, 村山繁雄, 齊藤祐子, 野中隆, 長谷川成人. 神経変性疾患におけるTMEM106Bアミロイドの局在. Dementia Japan. 2023. 37. 4. 680-680
Ranabir Chakraborty, Takashi Nonaka, Masato Hasegawa, Chiara Zurzolo. Tunnelling nanotubes between neuronal and microglial cells allow bi-directional transfer of α-Synuclein and mitochondria. Cell death & disease. 2023. 14. 5. 329-329
Yuya Kishino, Koji Matsukawa, Taisei Matsumoto, Ryota Miyazaki, Tomoko Wakabayashi, Takashi Nonaka, Fuyuki Kametani, Masato Hasegawa, Tadafumi Hashimoto, Takeshi Iwatsubo. Casein kinase 1δ/ε phosphorylates fused in sarcoma (FUS) and ameliorates FUS-mediated neurodegeneration. Journal of Biological Chemistry. 2022. 102191-102191
Shiori Awa, Genjiro Suzuki, Masami Masuda-Suzukake, Takashi Nonaka, Minoru Saito, Masato Hasegawa. Phosphorylation of endogenous α-synuclein induced by extracellular seeds initiates at the pre-synaptic region and spreads to the cell body. Scientific reports. 2022. 12. 1. 1163-1163

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MISC (75)：

渡辺亮平, 東晋二, 野中隆, 河上緒, 大島健一, 新里和弘, 秋山治彦, 吉田眞理, 長谷川成人, 新井哲明. FTLD-TDP患者におけるAtaxin-2の局在・発現量解析. Dementia Japan. 2021. 35. 4. 611-611
河上緒, 品川俊一郎, 根本清貴, 峰村明里, 高崎恵美, 雨宮きよみ, 大島健一, 新里和弘, 渡辺亮平, 野中隆, et al. 意味性認知症の臨床症候および神経画像変化からみた病態進展機序の検討. Dementia Japan. 2021. 35. 4. 627-627
Tatsuo Mano, Takashi Nonaka, Airi Tarutani, Tadafumi Hashimoto, Shigeo Murayama, Masato Hasegawa, Takeshi Iwatsubo, Atsushi Iwata. Tau-related dysfunction of BRCA1 lead to reduced neuronal plasticity in Alzheimer's disease. NEUROLOGY. 2018. 90
細川雅人, 野中隆, 新井哲明, 新井哲明, 亀谷富由樹, 近藤ひろみ, 秋山治彦, 長谷川成人. TDP-43proteinopathyモデルマウスの作製. 日本薬学会年会要旨集(CD-ROM). 2017. 137th. ROMBUNNO.27I-am09
樽谷愛理, 樽谷愛理, 鈴木元治郎, 下沢明希, 下沢明希, 野中隆, 久永真市, 長谷川成人. どのような性状のαシヌクレインがプリオン様伝播のシードとなるか?. Dementia Japan. 2016. 30. 4. 596

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Education (4)：

- 1996 Saitama University
- 1996 Saitama University Graduate School, Division of Science and Engineering
- 1991 Saitama University Faculty of Science
- 1991 Saitama University Faculty of Science

Professional career (1)：

(BLANK)

Association Membership(s) (2)：

日本生化学会 , 日本認知症学会

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