Research field (5):
Systems genomics
, Genomics
, Radiology
, Medical biochemistry
, Molecular biology
Research keywords (2):
ゲノム科学
, Genome science
Research theme for competitive and other funds (18):
2018 - 2023 癌放射線治療における稀で重篤な正常組織障害発症例のゲノムシーケンス解析
2019 - 2022 口腔粘膜悪性黒色腫の重粒子線治療を中心とした集学的治療法の開発
2013 - 2016 Basic Research for Carbon-Ion Radiotherapy for Breast Cancer
2013 - 2016 Metabolome analysis of invaded pancreatic cancer cell line, PANC-1, after irradiation
2012 - 2016 A study for single nucleotide polymorphism as a risk factor correlating to radiation pneumonitis after stereotactic body radiotherapy for non-small celllung cancer.
2012 - 2015 Research on new mechanism for radioprotective effect of FGF12
2006 - 2008 Identification of single nucletide polymorphisms that affect the esophageal carcinogenesis and clinical application for tailor-made medicine
2005 - 2007 Gene profile analysis concerning mandibular bone invasion of oral cancer
2001 - 2006 放射線感受性遺伝子解析
1998 - 1999 Analyses of transcriptional regulation and function of NPAT gene which shares a promoter witn ATM gene.
1994 - 1994 多発性内分泌腺腫瘍症1型原因遺伝子の単離とその解析
1992 - 1993 多発性内分泌腺腫瘍症1型の原因遺伝子の同定
1991 - 1993 Information Exchange on Cancer Research with North American Countries.
1988 - 1989 Construction of Ordered-Clones Library for Human Chromosome 21
Human genome analysis
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Papers (148):
Liqiu Ma, Yoshimitsu Sakamoto, Ken Ando, Hidetoshi Fujita, Akihisa Takahashi, Tsuguhide Takeshima, Hiromi Otsuka, Daniel K Ebner, Kazuhiro Kakimi, Takashi Imai, et al. Th Balance-Related Host Genetic Background Affects the Therapeutic Effects of Combining Carbon-Ion Radiation Therapy With Dendritic Cell Immunotherapy. International journal of radiation oncology, biology, physics. 2022. 112. 3. 780-789
K E Applegate, W Rühm, A Wojcik, M Bourguignon, A Brenner, K Hamasaki, T Imai, M Imaizumi, T Imaoka, S Kakinuma, et al. Individual response of humans to ionising radiation: governing factors and importance for radiological protection. Radiation and Environmental Biophysics. 2020. 59. 2. 185-209
Liqiu Ma, Yoshimitsu Sakamoto, Akinori Kanai, Hiromi Otsuka, Akihisa Takahashi, Kazuhiro Kakimi, Takashi Imai, Takashi Shimokawa. Characterization of a Novel Murine Colon Carcinoma Subline with High-Metastatic Activity Established by In Vivo Selection Method. International journal of molecular sciences. 2020. 21. 8
Matsuura T, Maru Y, Izumiya M, Hoshi D, Kato S, Ochiai M, Hori M, Yamamoto S, Tatsuno K, Imai T, et al. Organoid-based ex vivo reconstitution of Kras-driven pancreatic ductal carcinogenesis. Carcinogenesis. 2019. 41. 4. 490-501
Daino K, Ishikawa A, Suga T, Amasaki Y, Kodama Y, Shang Y, Hirano-Sakairi S, Nishimura M, Nakata A, Yoshida M, et al. Mutational landscape of T-cell lymphoma in mice lacking the DNA mismatch repair gene Mlh1: no synergism with ionizing radiation. Carcinogenesis. 2019. 40. 2. 216-224
Variants Of Cell-Cycle Regulatory Genes Are Associated With The Risk Of An Early Adverse Reaction After Radiotherapy For Cervical Cancer
(Biotecnologia Habana 2009, Medical Applications of Biotechnology 2009)
Genetic Variation in Individual Sensitivity to Clinical Radiotherapy
(Genomic Tools & Technologies Summit 2009)
Genetic Variation in Individual Sensitivity to Clinical Radiotherapy
(KIDS workshop 2009 in NIRS IAEA NIRS Joint Workshop & NIRS Symposium on Radiation Protection for Children 2009)
The Japanese RadGenomics Project
(International radiogenomics collaboration to predict radiotherapy outcome 2009)
Variants Of Cell-Cycle Regulatory Genes Are Associated With The Risk Of An Early Adverse Reaction After Radiotherapy For Cervical Cancer
(Biotecnologia Habana 2009, Medical Applications of Biotechnology 2009)
2018/04 - 現在 National Institute of Radiological Sciences National Institute for Quantum and Radiological Science and Technology Medical Databank, Hospital & Department of Charged Particle Therapy Research
2016/04 - 2018/03 National Institute for Quantum and Radiological Science and Technology National Institute of Radiological Sciences Supreme Researcher
2011/04 - 2016 放射線医学総合研究所 プログラムリーダー
2006 - 2011 - 放射線医学総合研究所 グループリーダー
2001 - 2006 放射線医学総合研究所 プロジェクトリーダー
1994 - 2001 放射線医学総合研究所 主任研究員
1994 - 2001 Senior Researcher, National Institute of
2001 - - Director, National Institute of Radiological
1991 - 1994 (財)癌研究会癌研究所 研究員
1991 - 1994 Researcher, Cancer Institute
1987 - 1991 理化学研究所 研究員
1987 - 1991 Researcher, Institute of Physical and Chemical
Sciences
Radiological Sciences
Researches
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Awards (2):
2001 - ヒトゲノム国際会議2001 ポスター賞
2001 - Human Genome Meeting 2001 Poster Competition
Association Membership(s) (6):
日本癌学会
, 日本生化学会
, 日本放射線影響学会
, Japanese Cancer Association
, Japanese Biochemical Society
, Japan Radiation Research Society