Rchr
J-GLOBAL ID:200901096484529138   Update date: Nov. 07, 2024

Hattori Mitsuharu

ハットリ ミツハル | Hattori Mitsuharu
Homepage URL  (1): http://www.phar.nagoya-cu.ac.jp/hp/bsk/indexj1.html
Research field  (5): Neuroanatomy and physiology ,  Neuroscience - general ,  Functional biochemistry ,  Pharmacology ,  Pharmaceuticals - health and biochemistry
Research keywords  (16): P4-ATPase ,  リン脂質 ,  プロテオリシス ,  トラフィッキング ,  蛋白質分解 ,  リーリン ,  変異マウス ,  受容体 ,  遺伝子 ,  axon guidance ,  神経 ,  神経発生 ,  Eph ,  PAF ,  細胞移動 ,  脳
Research theme for competitive and other funds  (24):
  • 2024 - 2026 リーリン経路と細胞膜非対称性の破綻による疾患発症の分子機構解明と、創薬標的の同定
  • 2021 - 2023 Developing methods to improve neuronal function by targeting membrane fluidity in neurons.
  • 2020 - 2023 精神疾患の理解と治療を志向した、分泌タンパク質リーリンの基礎および応用研究
  • 2019 - 2021 Control of neuronal morphology by using a specific fatty acid
  • 2017 - 2020 The role of a secreted protein Reelin in the brain and its therapeutic application.
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Papers (101):
  • Takao Kohno, Ikuma Nakagawa, Airi Taniguchi, Fang Heng, Mitsuharu Hattori. Biochemical characterizations of the central fragment of human Reelin and identification of amino acid residues involved in its secretion. The Journal of Biochemistry. 2024
  • Mitsuki Hara, Keisuke Ishii, Mitsuharu Hattori, Takao Kohno. EphA4 Induces the Phosphorylation of an Intracellular Adaptor Protein Dab1 <i>via</i> Src Family Kinases. Biological and Pharmaceutical Bulletin. 2024. 47. 7. 1314-1320
  • Noe Kaneko, Kumiko Hirai, Minori Oshima, Kei Yura, Mitsuharu Hattori, Nobuaki Maeda, Chiaki Ohtaka-Maruyama. ADAMTS2 regulates radial neuronal migration by activating TGF-β signaling at the subplate layer of the developing neocortex. EMBO reports. 2024. 25. 7. 3090-3115
  • Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, et al. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. eLife. 2024. 12
  • Keisuke Ishii, Takao Kohno, Mitsuharu Hattori. Postnatal injection of Reelin protein into the cerebellum ameliorates the motor functions in reeler mouse. Neuroscience Research. 2023. 194. 7-14
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MISC (65):
Patents (1):
Professional career (1):
  • 博士(薬学) (東京大学)
Work history (7):
  • 2009 - 現在 Nagoya City University Graduate School of Pharmaceutical Sciences
  • 2007 - 2009 Nagoya City University Graduate School of Pharmaceutical Sciences
  • 2004 - 2007 Nagoya City University Graduate School of Pharmaceutical Sciences
  • 2002 - 2006 科学技術振興機構 さきがけ研究員
  • 1999 - 2004 The University of Tokyo The Institute of Medical Science
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Committee career (11):
  • 2024/05 - 現在 日本生化学会中部支部会 幹事
  • 2024/01 - 現在 日本生化学会「生化学」企画委員長
  • 2023/11 - 現在 日本生化学会 代議員
  • 2023/04 - 現在 日本薬学会 代議員
  • 2022/04 - 現在 Biological and Pharmaceutical Bulletin Editor-in-Chief
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Awards (1):
  • 1997 - Amersham and Science Magazine Prize for Young Scientists
Association Membership(s) (7):
日本神経化学会 ,  日本脂質生化学会 ,  北米神経科学会 ,  日本分子生物学会 ,  日本薬学会 ,  日本生化学会 ,  日本神経科学学会
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