Rchr
J-GLOBAL ID：200901096797997833
Update date: Sep. 06, 2024
Morita Izumi
モリタ イズミ | Morita Izumi
Affiliation and department：
Research field (2)：
Tertiary education
, Pharmaceuticals - analytical and physicochemistry
Research keywords (5)：
薬学教育
, 薬品製造学
, 分析化学
, Medicinal Chemistry
, Analytical Chemistry
Research theme for competitive and other funds (22)：
- 2019 - 2022 Construction of innovative strategy for selecting improved antibody fragments as the platform generating next-generation diagnostic reagents
- 2019 - 2022 Construction of efficient systems for generation of anti-metatypic antibody for high-sensitive detection of small molecules
- 2019 - 2022 Development of new assay system for on-site analysis targeting hallucinogenic compounds in mushrooms
- 2016 - 2019 Development of new immunoassay systems for on-site analysis targeting stimulant amines
- 2016 - 2019 Efficient generation of high-affinity mutated antibodies based on a single virion direct fluorescence detection of antibody-displaying phage
- 2016 - 2019 覚せいアミン類のオンサイト検出を目的とする新規イム ノアッセイシステムの開発
- 2015 - 2018 Efficient systems for generating high-performance antibody mutants that enable sensitive determinations of diagnostic biomarkers
- 2013 - 2016 Generation of "antibody-like" proteins based on evolutionary molecular engineering for novel clinical diagnostics
- 2013 - 2016 進化分子工学を基盤とする新規な「抗体様」臨床検査薬 の創製と応用
- 2013 - 2015 Generation and clinical application of low-molecular-weight functional domain proteins.
- 2011 - 2013 抗体工学的アプローチによる新世代受動喫煙評価システ ムの開発
- 2011 - 2012 Development of a "new generation" monitoring system of passive smoking based on antibody engineering approach
- 2010 - 2012 Generation of recombinant antibody libraries that facilitate highly sensitive monitoring of low molecular weight biomarkers
- 2008 - 2010 Development and application of the high-throughput prediction method of activity for the bioactive substances
- 2007 - 2008 Development of monitoring systems for bioactive haptens with high sensitivity using "nano-antibodies" as a molecular recognition unit
- 2006 - 2007 Development of the anti-cancer promoting activity prediction method for the quinones which assume oxidation-reduction potential as a key parameter
- 2005 - 2006 Highly sensitive immunosensing based on new generation antibodies against a hapten-acceptor complex
- 2003 - 2004 Generation of mutant antibodies with ultrahigh affinity based on a novel and universal selection method and their application to trace analysis
- キノン類を含んだ植物の含有成分研究とその抗ガン活性
- Diels-Alder反応,及びOxime O-allyl etherの熱転位反応を用いたピリジン誘導体の合成研究
- Study on the Constituents of the Plant containing Quinones and the Antitumor Activity of them
- Synthesis of Pyridine Related Compounds by Diels-Alder Reaction and the Thermolysis of Oxime O-allyl Ether
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Papers (58)：
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Takashi Ohgita, Koto Sakai, Nodoka Fukui, Norihiro Namba, Miyu Nakano, Yuki Kiguchi, Izumi Morita, Hiroyuki Oyama, Kouya Yamaki, Kohjiro Nagao, et al. Generation of novel anti-apoE monoclonal antibodies that selectively recognize apoE isoforms. FEBS letters. 2024. 598. 8. 902-914
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Takashi Ohgita, Hiroki Kono, Izumi Morita, Hiroyuki Oyama, Toshinori Shimanouchi, Norihiro Kobayashi, Hiroyuki Saito. Intramolecular interaction kinetically regulates fibril formation by human and mouse α-synuclein. Scientific reports. 2023. 13. 1. 10885-10885
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Yuki Kiguchi, Izumi Morita, Kouya Yamaki, Shigehiko Takegami, Norihiro Kobayashi. Framework-Directed Amino-Acid Insertions Generated over 55-Fold Affinity-Matured Antibody Fragments That Enabled Sensitive Luminescent Immunoassays of Cortisol. Biological & pharmaceutical bulletin. 2023. 46. 12. 1661-1665
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Jiulong Su, Bo Zhu, Akihito Inoue, Hiroyuki Oyama, Izumi Morita, Jinhua Dong, Takanobu Yasuda, Yoshiko Sugita-Konishi, Tetsuya Kitaguchi, Norihiro Kobayashi, et al. The Patrol Yeast: A new biosensor armed with antibody-receptor chimera detecting a range of toxic substances associated with food poisoning. Biosensors & bioelectronics. 2022. 219. 114793-114793
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上田 宏, 蘇 九龍, 朱 博, 井上 暁人, 大山 浩之, 森田 いずみ, 董 金華, 小西 良子, 北口 哲也, 小林 典裕, et al. 各種食中毒から生活者を守る「パトロール酵母」の開発. 日本生物工学会大会講演要旨集. 2022. 2022年. 135-135
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Education (2)：
- - 1995 Kobe Pharmaceutical University Faculty of Pharmacy Pharmaceutical Science
- - 1995 Kobe Pharmaceutical University Faculty of Pharmaceutical Science
Association Membership(s) (5)：
日本薬学教育学会
, 生物化学測定研究会
, 日本法中毒学会
, 日本分析学会
, 日本薬学会
