Maeda Hatsuo

• 2020 - 2023 Design of fluorescent probes for dynamic analysis of polysufides and proteins modified by polysulfidation
• 2018 - 2022 Evaluation of the color change and combination in colored pharmaceuticals to make their discrimination more difficult under different light sources, establishing safer and more secure medication.
• 2017 - 2021 Scientific design of the tasting scales for Japanese Sakes and the method transforming the physical factors of Sakes into the scores on the scale, to help expanding the Japanese Sake market.
• 2015 - 2018 Consideration on the color design that effectively allows identification of medicine by intuition at the time of a disaster -Verification through color psychological research-
• 2012 - 2015 Strategy proposal of drug color design to improve malpractice and adherence on medication
2012 - 2015 Development of See-easy Drag Tray for Safer Medication on Partially Color-Blind Persons
2009 - 2011 新規蛍光色素の開発
2009 - 2010 近赤外蛍光イメージングに資する新規蛍光色素の戦略的開発
2007 - 2008 Design of fluorescent probes for reversible sensing redox cycles coupled with oxidative stress
2006 - 2007 A Comprehensive Study on the Effect of Human Genetic Polymorphism on the Drug Metabolizing, Properties of CYP
2005 - 2007 新規蛍光キナーゼアッセイの構築
2005 - 2007 活性酸素高特異的蛍光プローブの設計開発に基づくバイオイメージング法および活性酸素消去能評価法の構築
2000 - 2006 Design of fluorescent probes for bio-imaging of cell-derived reactive oxygen species (ROS)
2005 - 2005 Development of selenol fluorescent probes and their application to determination of selenocysteine and selenoproteins
2003 - 2005 Strategic development of fluorescent probes applicable to in vivo dynamic analysis of hydrogen peroxide
2003 - 2005 Design of a novel system for kinase assay
2004 - 2004 進化はいかにして環境毒と戦ってきたか-総合的な化学動態分析による陸域・海域生態系の新比較手法の開発をめざして-
2000 - 2001 レゾルフィン類/フラビン酵素系を用いる新規生体分析法の開発
1999 - 2001 Development of novel electroanalytical media for medicinal and environmental pharmaceutical sciences based on the surface modification of electrodes
1997 - 1998 陰極還元電位を指標とする合成反応剤の設計・開発
1995 - 1995 テトラフルオロボレイトアニオンをフッ素源として用いる電解フッ素化反応の開発
1994 - 1994 テトラフルオロボレイトアニオンをフッ素源として用いるフッ素化反応の開発

• Koji Tsukamoto, Shota Shimabukuro, Miyuki Mabuchi, Hatsuo Maeda. A Naphthalimide-Based Cd2+ Fluorescent Probe with Carbamoylmethyl Groups Working as Chelators and PET-Promoters under Neutral Conditions. CHEMISTRY-A EUROPEAN JOURNAL. 2016. 22. 25. 8579-8585
• Koji Tsukamoto, Shogo Iwasaki, Mani Isaji, Hatsuo Maeda. An anthracene-based Cd2+ fluorescent chemosensor with a 4,7-bis(2-hydroxyethyl)-9-hydroxy-1,4,7-triazanonyl group as a highly selective chelator to Cd2+ over Zn2+. TETRAHEDRON LETTERS. 2013. 54. 45. 5971-5973
• Koji Tsukamoto, Yuka Shinohara, Shogo Iwasaki, Hatsuo Maeda. A coumarin-based fluorescent probe for Hg2+ and Ag+ with an N '-acetylthioureido group as a fluorescence switch. CHEMICAL COMMUNICATIONS. 2011. 47. 17. 5073-5075
• A. Okano, K. Tsukamoto, S. Kosaka, H. Maeda, S. Oishi, T. Tanaka, N. Fujii, H. Ohno. Synthesis of fused and linked bicyclic nitrogen heterocycles by palladiumcatalyzed domino cyclization of propargyl bromides. Chemistry - A European Journal. 2010. 16. 28. 8410-8418

• Akinori Okano, Hiroaki Ohno, Shohei Kosaka, Miyo Ohata, Kotaro Ishihara, Koji Tsukamoto, Hatsuo Maeda, Tetsuaki Tanaka, Nobutaka Fujii. Direct construction of bicyclic heterocycles by Pd(0)-catalyzed domino cyclization of propargyl bromides. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2009. 238
• Hiroaki Ohno, Akinori Okano, Shohei Kosaka, Koji Tsukamoto, Miyo Ohata, Kotaro Ishihara, Hatsuo Maeda, Tetsuaki Tanaka, Nobutaka Fujii. Direct construction of bicyclic heterocycles by palladium-catalyzed domino cyclization of propargyl bromides. ORGANIC LETTERS. 2008. 10. 6. 1171-1174
• Hiroaki Ohno, Akinori Okano, Shohei Kosaka, Koji Tsukamoto, Miyo Ohata, Kotaro Ishihara, Hatsuo Maeda, Tetsuaki Tanaka, Nobutaka Fujii. Direct construction of bicyclic heterocycles by palladium-catalyzed domino cyclization of propargyl bromides. ORGANIC LETTERS. 2008. 10. 6. 1171-1174
• Hatsuo Maeda. Which are you watching, an individual reactive oxygen species or total oxidative stress?. Annals of the New York Academy of Sciences. 2008. 1130. 149-156
• Hatsuo Maeda. Which are you watching, an individual reactive oxygen species or total oxidative stress?. FLUORESCENCE METHODS AND APPLICATIONS: SPECTROSCOPY, IMAGING, AND PROBES. 2008. 1130. 149-156

ｍore...

• 計算実践トレーニング帳
  化学同人 2009 ISBN:9784759811650
• スタンダード薬学シリーズ2 物理系薬学IV.演習編
  東京化学同人 2008 ISBN:9784807914715
• ベーシック機器分析化学
  化学同人 2008 ISBN:9784759811445
• パートナー分析化学I
  南江堂 2007
• 分析科学(ベーシック薬学教科書シリーズ2)
  化学同人 2007 ISBN:9784759812527

ｍore...

• Ph. D of Pharmaceutical Sciences (Osaka University)
• 薬学修士

• Analytical Sciences 誌 編集委員

• 2009 - ひょうごユニバーサル社会づくり賞・知事賞
• 1998 - 日本薬学会近畿支部奨励賞

日本分析化学会 ,  アメリカ化学会(American Chemical Sociaty) ,  電気化学協会 ,  有機合成化学協会 ,  日本化学会 ,  日本薬学会 ,  The Society of Synthetic Organic Chemistry ,  American Chemical Society ,  Tha Japan Society for Analytical Chemistry ,  The Chemical Society of Japan ,  Pharmaceutical Society of Japan