Tokinaga Yasuyuki

トキナガヤスユキ | Tokinaga Yasuyuki

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Anesthesiology

Research keywords (2)：麻酔薬 , Anesthetics

Research theme for competitive and other funds (8)：

2022 - 2025 内皮グリコカリックス障害を起こす機序の解明およびあらたな輸液戦略の開発
2021 - 2024 新規分子を標的とした痒み治療薬の開発に向けた末梢神経における痒み伝達の解明
2017 - 2020 The restoring effect of anesthetics on damaged-endothelial glycocalyx
2013 - 2016 The restoring effect of anesthetics on damaged-endothelial glycocalyx
2009 - 2010 The effect of volatile anesthetics on calcium oscillation in astrocyte

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Papers (8)：

Tomohiro Chaki, Shunsuke Tachibana, Sho Kumita, Honami Sato, Kosuke Hamada, Yasuyuki Tokinaga, Michiaki Yamakage. Head Rotation Reduces Oropharyngeal Leak Pressure of the i-gel and LMA® SupremeTM in Paralyzed, Anesthetized Patients: A Randomized Trial. Anesthesia and analgesia. 2021. 132. 3. 818-826
Yasuaki Sawashita, Naoyuki Hirata, Yusuke Yoshikawa, Hirofumi Terada, Yasuyuki Tokinaga, Michiaki Yamakage. Remote ischemic preconditioning reduces myocardial ischemia-reperfusion injury through unacylated ghrelin-induced activation of the JAK/STAT pathway. Basic research in cardiology. 2020. 115. 4. 50-50
Tomohiro Chaki, Naoyuki Hirata, Yusuke Yoshikawa, Shunsuke Tachibana, Yasuyuki Tokinaga, Michiaki Yamakage. Lipid emulsion, but not propofol, induces skeletal muscle damage and lipid peroxidation. Journal of anesthesia. 2019. 33. 6. 628-635
Mikako Kusakai, Atsushi Sawada, Natsumi Kii, Yasuyuki Tokinaga, Naoyuki Hirata, Michiaki Yamakage. Epidural anesthesia combined with sedation with dexmedetomidine for appendectomy in a patient with amyotrophic lateral sclerosis: a case report. JA clinical reports. 2018. 4. 1. 82-82
Yusuke Yoshikawa, Naoyuki Hirata, Ryoichi Kawaguchi, Yasuyuki Tokinaga, Michiaki Yamakage. Dexmedetomidine Maintains Its Direct Cardioprotective Effect Against Ischemia/Reperfusion Injury in Hypertensive Hypertrophied Myocardium. Anesthesia and analgesia. 2018. 126. 2. 443-452

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MISC (7)：

UEMATSU Nobuhiko, OGAWA Koji, TOKINAGA Yasuyuki, TANGE Kazuaki, HATANO Yoshio. Sevoflurane inhibits angiotensin II-induced Rho kinase-mediated contraction of vascular smooth muscle from spontaneously hypertensive rat. 2011. 25. 3. 398-404
Toshiyuki Minonishi, Koji Ogawa, Yasuyuki Tokinaga, Takaaki Negoro, Yoshiki Kimoto, Yoshio Hatano. Differential vasodilation response to olprinone in rabbit renal and common carotid arteries. JOURNAL OF ANESTHESIA. 2010. 24. 1. 61-66
Feng Qi, Koji Ogawa, Yasuyuki Tokinaga, Nobuhiko Uematsu, Toshiyuki Minonishi, Yoshio Hatano. Volatile Anesthetics Inhibit Angiotensin II-Induced Vascular Contraction by Modulating Myosin Light Chain Phosphatase Inhibiting Protein, CPI-17 and Regulatory Subunit, MYPT1 Phosphorylation. ANESTHESIA AND ANALGESIA. 2009. 109. 2. 412-417
Y. Tokinaga, K. Ogawa, J. Yu, T. Kuriyama, T. Minonishi, Y. Hatano. Mechanism of the ropivacaine-induced increase in intracellular Ca2+ concentration in rat aortic smooth muscle. ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2007. 51. 9. 1155-1160
Ai Ishikawa, Koji Ogawa, Yasuyuki Tokinaga, Nobuhiko Uematsu, Kazuhiro Mizumoto, Yoshio Hatano. The mechanism behind the inhibitory effect of isoflurane on angiotensin II-Induced vascular contraction is different from that of sevoflurane. ANESTHESIA AND ANALGESIA. 2007. 105. 1. 97-102

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Professional career (1)：

Association Membership(s) (1)：

日本麻酔科学会

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