Research field (4)：
Immunology
, Pharmacology
, Pharmaceuticals - health and biochemistry
, Functional biochemistry
Research theme for competitive and other funds (23)：
2013 - 2017 Selenium-transport mechanism of selenoprotein P
2004 - 2005 必須微量元素セレン・トランスポーター受容体の同定と取り込み機構の解析
2000 - 2001 必須微量元素セレンを運搬する蛋白質の同定と運搬機構の解析
1998 - 2000 Studies on effector molecules of innate immunity responsible for cytotoxicity to tumor cells.
1997 - 1999 Studies on effector molecules of innate immunity responsible for cytotoxicity to tumor cells.
1997 - 1998 新規,細胞増殖因子としてのセレン含有蛋白質の探索
1996 - 1997 APOPTOSIS AND COMPLEMENT-STUDIES ON THE MECHANISM OF COMPKEMENT ACTIVATION AND THE BIOLOGICAL SIGNIFICANCE
1996 - 1996 21番目のアミノ酸の翻訳に関与する新規RNA結合因子の研究
1995 - 1995 HIV-I構成蛋白やセレン含有蛋白の翻訳に必須な新規RNA結合因子の探索
1994 - 1995 STUDIES ON THE BIOLOGICAL FUNCTIONS OF THE COMPLEMENT SYSTEM
1994 - 1994 細胞の生存維持・増殖に必須なセレン含有因子の探索
1994 - 1994 ヒトSOD遺伝子導入マウスを用いた神経損傷におけるSOD保護効果の研究
1992 - 1993 Studies on molecular constitution and effector functions of complement system
1990 - 1990 ヒト食細胞の抗体レセプタ-の構造と機能に関する生化学的研究
1989 - 1990 Studies on the Molecular Mechanisms of Regulation of Activation of Various Functions in Phagocytes
1989 - 1989 補体系による外因系血液凝固の活性化と制御に関する研究
1988 - 1989 Analysis of the molecular pathology of chronic granulomatous disease by assay of the components of the NADPH oxidase
1988 - 1988 補体系による外因系血液凝固の活性化と制御に関する研究
1987 - 1988 Biochemical Studies on Human Inter- trypsin Inhibitor
1987 - 1988 Studies on the molecular mechanisms by which phagocytes recognize and eliminate antigens
グルタチオンペルオキシダーゼの機能に関する研究
Study on Fc R- and CR-mediated functions of human neutrophils
Study on Function of Glutathione Peroxidase
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Papers (18)：
Mutsumi Tanaka, Yoshiro Saito, Hirofumi Misu, Seiji Kato, Yuki Kita, Yumie Takeshita, Takehiro Kanamori, Toru Nagano, Masatoshi Nakagen, Takeshi Urabe, et al. Development of a Sol Particle Homogeneous Immunoassay for Measuring Full-Length Selenoprotein P in Human Serum. Journal of Clinical Laboratory Analysis. 2016. 30. 114-122
Yoshiro Saito, Mototada Shichiri, Takashi Hamajima, Noriko Ishida, Yuichiro Mita, Shohei Nakao, Yoshihisa Hagihara, Yasukazu Yoshida, Kazuhiko Takahashi, Etsuo Niki, et al. Enhancement of lipid peroxidation and its amelioration by Vitamin E in a subject with mutations in the SBP2 gene. Journal of Lipid Research. 2015. 56. 2172-2182
Kazuhide Ishikura, Hirofumi Misu, Masafumi Kumazaki, Masafumi Kumazaki, Hiroaki Takayama, Naoto Matsuzawa-Nagata, Naoto Matsuzawa-Nagata, Natsumi Tajima, Keita Chikamoto, Fei Lan, et al. Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells. Diabetologia. 2014. 57. 9. 1968-1976
Basilua Andre Muzembo, Narongpon Dumavibhat, N'landu Roger Ngatu, Masamitsu Eitoku, Ryoji Hirota, Shinichi Kondo, Yoji Deguchi, Yoshiro Saito, Kazuhiko Takahashi, Narufumi Suganuma. Serum selenium and selenoprotein P in patients with silicosis. Journal of Trace Elements in Medicine and Biology. 2013. 27. 1. 40-44
Hirofumi Misu, Kazuhide Ishikura, Seiichiro Kurita, Yumie Takeshita, Tsuguhito Ota, Yoshiro Saito, Kazuhiko Takahashi, Shuichi Kaneko, Toshinari Takamura. Inverse correlation between serum levels of selenoprotein p and adiponectin in patients with type 2 diabetes. PLoS ONE. 2012. 7. 4. e34952
