Koga Mitsuhisa

コガミツヒサ | Koga Mitsuhisa

Affiliation and department：

Research field (1)： Clinical pharmacy

Research theme for competitive and other funds (12)：

2021 - 2024 新規ビタミンEエステル型プロドラッグによるNASHに関連した心血管リスク抑制効果
2020 - 2023 飲酒量低減薬ナルメフェンによる動脈硬化症の発症機序
2018 - 2021 The role of pericytes in the development of epileptogenesis after traumatic brain injury
2018 - 2021 Exacerbation mechanism of atherosclerosis progression by varenicline in hyperuricemia
2017 - 2020 Varenicline, a smoking cessation drug, improves alveolar expansion and inflammation in elastase-induced lung damage

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Papers (45)：

Shotaro Goto, Shuichi Setoguchi, Daisuke Watase, Hirofumi Yamakawa, Ayano Yamada, Mitsuhisa Koga, Koichi Matsuo, Kazuhisa Matsunaga, Yoshiharu Karube, Jiro Takata. Menahydroquinone-4 may play a key role in regulating CCL5 expression induced by epidermal growth factor receptor inhibitors. Scientific Reports. 2023. 13. 1
Kentaro Aono, Junichi Matsumoto, Taichi Matsumoto, Mitsuhisa Koga, Keisuke Migita, Koji Tominaga, Shinsuke Nakagawa, Atsushi Yamauchi. Association of T cell infiltration and morphological change of thymus gland with the aggravation of pulmonary emphysema in testosterone deficiency. Biochemistry and biophysics reports. 2023. 34. 101489-101489
Mariko Hirano-Kusuda, Shuichi Setoguchi, Mitsuhisa Koga, Shotaro Goto, Ayano Yamada, Daisuke Watase, Nami Nagata-Akaho, Yoshiharu Karube, Kazuhisa Matsunaga, Jiro Takata. Cationic Ester Prodrugs of Curcumin with N,N-dimethyl Amino Acid Promoieties Improved Poor Water Solubility and Intestinal Absorption. Pharmaceutical Research. 2023
Erina Toki, Shotaro Goto, Shuichi Setoguchi, Kazuki Terada, Daisuke Watase, Hirofumi Yamakawa, Ayano Yamada, Mitsuhisa Koga, Kaori Kubota, Katsunori Iwasaki, et al. Delivery of the reduced form of vitamin K2(20) to NIH/3T3 cells partially protects against rotenone induced cell death. Scientific Reports. 2022. 12. 1
Koshun Inada, Mitsuhisa Koga, Ayano Yamada, Shinya Dohgu, Atsushi Yamauchi. Moxifloxacin induces aortic aneurysm and dissection by increasing osteopontin in mice. Biochemical and biophysical research communications. 2022. 629. 1-5

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MISC (20)：

牛島望, 瀬戸口修一, 後藤将太朗, 山川博文, 渡瀬大輔, 古賀允久, 高田二郎. Ubiquinol-10のイオン性エステル型プロドラッグ化によるUbiquinone-10光毒性の克服およびヒト表皮角化細胞を用いた送達性の評価. 日本薬剤学会年会講演要旨集. 2020. 35年会. 228-228
境理那, 瀬戸口修一, 後藤将太朗, 山川博文, 渡瀬大輔, 古賀允久, 高田二郎. Ubiquinol-10のイオン性エステル誘導体化による光安定性向上と水性製剤化検討. 日本薬剤学会年会講演要旨集. 2020. 35年会. 229-229
後藤将太朗, 瀬戸口修一, 渡瀬大輔, 寺田一樹, 山川博文, 土岐衣梨奈, 古賀允久, 松永和久, 加留部善晴, 高田二郎. 皮膚適用を企図するフィロヒドロキノン(活性型ビタミンK1)エステル誘導体の光安定性と皮膚送達性の評価. 日本薬剤学会年会講演要旨集. 2020. 35年会. 229-229
山川博文, 後藤将太朗, 瀬戸口修一, 渡瀬大輔, 寺田一樹, 土岐衣梨奈, 古賀允久, 松永和久, 加留部善晴, 高田二郎. Ubiquinol-10エステル誘導体化によるUbiquinol-10及びUbiquinone-10の光不安定性と光毒性の克服及び表皮角化細胞への送達性. ビタミン. 2020. 94. 4. 285-285
冨永宏治, 青野健太郎, 松本純一, 古賀允久, 山内淳史, 江川孝, 片岡泰文. COPDモデルマウスにおけるリポキシンA4に対するエストロゲンの影響. 日本薬学会年会要旨集. 2020. 140年会. 26Q-pm097

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Education (1)：

2002 - 2007 Fukuoka University Graduate School, Division of Pharmaceutical Sciences Pharmaceutical Care and Health Sciences

Professional career (2)：

Doctor of Philosophy (Fukuoka University)
Ph.D.

Awards (1)：

2006/10 - American Society of Hypertension New Investigator Travel Award -Japanese Fellows (Supported by Pfizer) Interferon-Gamma-mediated pathway-new target for prevention of vascular remodeling after vascular injury-

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