Rchr
J-GLOBAL ID：201001008497305721
Update date: Sep. 28, 2024
Udaka Keiko
ウダカ ケイコ | Udaka Keiko
Affiliation and department：
Job title：
Specially appointed Professor
Homepage URL (1)：
http://www.kochi-ms.ac.jp/~ff_immnl/index.htm
Research field (1)：
Immunology
Research keywords (6)：
Peptide
, MHC
, T cell
, peptide
, MHC
, T cell
Research theme for competitive and other funds (37)：
- 2022 - 2025 Mechanism of kidney cancer development via immunodeficiency due to germline mutation of chromatin regulator
- 2022 - 2025 Development of new therapies based on immunological analysis of WT1 vaccine therapy for glioma stem cells
- 2021 - 2024 新型ウイルス感染症を標的とした新たな免疫治療法確立のための基盤研究
- 2019 - 2022 Rational design of the next-generation peptide immunotherapy which exploits tumor endothelial cells as an APC.
- 2018 - 2021 Analysis of endothelial cells presenting antigens to helper T cells in tumor microenvironment
- 2016 - 2021 Generation of neo-self peptides in tumors
- 2017 - 2020 Analysis of oral squamous cell carcinoma cell-derived exosomes for the development of new diagnostic and therapeutic methods
- 2017 - 2020 Development of Zika fever- and AIDS-peptide vaccine using next generation chip, T-ISAAC
- 2015 - 2018 Fabrication of highly active antigen nanocarriers by integration of immunity-inducing functions and their application to cancer immunotherapy
- 2014 - 2016 合目的機能の統合によるオールインワンナノメディシンの開発と非侵襲がん治療への展開
- 2011 - 2014 Effects of hypoxic environment and HIF-1 on antitumor immune response of oral squamous cell carcinoma
- 2011 - 2013 血管内皮細胞MHC分子の抗原提示能の解析と臨床応用
- 2009 - 2009 自己免疫性膵炎における特異的免疫応答の検討
- 2007 - 2009 進行・再発前立腺癌に対するPSAペプチド癌ワクチン及び新規アジュバントの開発
- 2007 - 2009 Construction of a system to develop immunotherapy by exploiting the computational algorithm to identify HLA-binding peptides.
- 2005 - 2006 小児の難治性EBウイルス感染症に対する効率的ペプチドワクチンの新規開発
- 2004 - 2004 HLA結合性ペプチド予測による免疫標的探索法の開発
- 2002 - 2002 ゲノムワイドのMHC class I結合性ペプチド探索自動化データベース
- 2000 - 2000 MHC class I分子結合性ガン抗原の探索とガン抗原認識機構の研究
- 1999 - 2000 MECHANISMS OF PROTECTION AGAINST RETROVIRAL INFECTIONS INDUCED WITH A SINGLE-EPITOPE CD4^+ T-CELL VACCINE
- 1998 - 1998 T細胞抗原の特異性の由来について
- 1997 - 1998 Studies on chicken immunoglobulin gene moditication and attinity maturation
- 1997 - 1998 Specificity analysis of cytotoxic T lymphocytes with peptide libraries.
- 1997 - 1997 ペプチドライブラリーを用いたCTLの特異性の解析
- 1997 - 1997 MHCとペプチドの相補的会合の研究
- 1997 - 1997 腫癌拒絶抗原の解析とペプチドワクチンの設計
- 1996 - 1996 ペプチドライブラリーを用いたCTLエピトープの解析
- 1996 - 1996 ペプチドライブラリーを用いたCTLエピトープの解析
- 1996 - 1996 ペプチドライブラリーを用いたMHC-ペプチド複合体の相補的安定化要因の解析
- 1996 - 1996 腫瘍拒絶抗原の解析とペプチドワクチンの検討
- 1995 - 1996 任意のT細胞エピトープ同定法の開発
- 1995 - 1995 ペプチドライブラリーを用いたMHC-ペプチド複合体の相補的安定化要因の解析
- T細胞認識
- 腫瘍免疫
- T細胞による自己非自己識別
- tumor immunology
- T cell recognition
Show all
Papers (49)：
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辛島 尚, 小松 利広, 山本 新九郎, 橋田 初音, 執印 太郎, 宇高 恵子, 井上 啓史. 腎癌におけるイミキモド経皮投与と抗-programmed cell death-1抗体の併用療法. 腎癌研究会会報. 2024. 54. 30-30
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Hiroko Nakajima, Jun Nakata, Kanako Imafuku, Hiromu Hayashibara, Kazuki Isokawa, Keiko Udaka, Fumihiro Fujiki, Soyoko Morimoto, Kana Hasegawa, Naoki Hosen, et al. Identification of mouse helper epitopes for WT1-specific CD4+ T cells. Cancer immunology, immunotherapy : CII. 2021. 70. 11. 3323-3335
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Eiji Yuba, Yoshikatsu Sugahara, Yuta Yoshizaki, Takeyuki Shimizu, Michiyuki Kasai, Keiko Udaka, Kenji Kono. Carboxylated polyamidoamine dendron-bearing lipid-based assemblies for precise control of intracellular fate of cargo and induction of antigen-specific immune responses. Biomaterials Science. 2021. 9. 8. 3076-3089
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Toshihiro Komatsu, Takeyuki Shimizu, Makoto Kanoh, Tomoya Miyakawa, Yoko Satta, Yoshiki Yasukochi, Rika Fujimoto, Motoki Tada, Kaori Machida, Sayo Kataoka, et al. Development of a novel monoclonal antibody that binds to most HLA-A allomorphs in a conformation-dependent yet peptide-promiscuous fashion. Immunogenetics. 2020. 72. 3. 143-153
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Kanekiyo S, Hazama S, Takenouchi H, Nakajima M, Shindo Y, Matsui H, Tokumitsu Y, Tomochika S, Tsunedomi R, Tokuhisa Y, et al. IgG response to MHC class I epitope peptides is a quantitative predictive biomarker in the early course of treatment of colorectal cancer using therapeutic peptides. Oncol Rep. 2018. 39. 5. 2385-2392
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MISC (42)：
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辛島 尚, 小松 利広, 新村 真由美, 川田 千明, 鎌田 雅行, 井上 啓史, 宇高 恵子, 黒田 直人, 執印 太郎. 腎癌にたいするImiquimodとSorafenibの新規併用療法. 日本泌尿器科学会総会. 2014. 102回. 526-526
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弓場英司, 能崎優太, 宇高恵子, 原田敦史, 河野健司. pH応答性高分子修飾リポソームによる抗原ペプチドデリバリーとそのがん免疫治療効果. 日本DDS学会学術集会プログラム予稿集. 2014. 30th
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Takayuki Ikezoe, Chie Nishioka, Jing Yang, Satoshi Serada, Tetsuji Naka, Akihito Yokoyama, Keiko Udaka. CD34(+)/CD38(-) Leukemia Stem Cells Aberrantly Express CD82 Adhesion Molecule. BLOOD. 2010. 116. 21. 895-895
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Kazuhiro Uesugi, Yoichi Hiasa, Yohei Koizumi, Toshie Mashiba, Masashi Hirooka, Ichiro Konishi, Yoshio Tokumoto, Masanori Abe, Bunzo Matsuura, Keiko Udaka, et al. UP-REGULATED WILMS' TUMOR 1 GENE FUNCTIONS IN ANTI-APOPTOSIS: POTENTIAL THERAPEUTIC TARGET FOR HEPATOCELLULAR CARCINOMA. HEPATOLOGY. 2010. 52. 4. 934A-934A
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Masaaki Kawashima, Nagamasa Maeda, Yoshihiro Adachi, Tamotsu Takeuchi, Yorito Yamamoto, Chiaki Izumiya, Kazutoshi Hayashi, Mutsuo Furihata, Keiko Udaka, Takao Fukaya. Human leukocyte antigen-G, a ligand for the natural killer receptor KIR2DL4, is expressed by eutopic endometrium only in the menstrual phase. FERTILITY AND STERILITY. 2009. 91. 2. 343-349
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Education (1)：
Professional career (1)：
Association Membership(s) (4)：
日本がん免疫学会
, 血液疾患免疫療法学会
, 日本生物物理学会
, 日本免疫学会
