Hiroyoshi Nishikawa

ニシカワヒロヨシ | Hiroyoshi Nishikawa

Affiliation and department：
Other affiliations (3)：

National Cancer Center
Nagoya University Graduate School of Medicine
糖鎖生命コア研究所細胞・個体制御部門教授

Homepage URL (1)： https://www.ncc.go.jp/jp/epoc/division/immunology/kashiwa/020/010/20170727180510.html

Research field (1)： Immunology

Research theme for competitive and other funds (15)：

2022 - 2025 Elucidation of regulation mechanisms of immune surveillance and tolerance by spatial multi-scale analysis of cancer
2017 - 2022 Association of immune responses with racial differences of cancer development
2017 - 2018 Immunosuppressive mechanisms for anti-tumor immune responses depending on antigenicity
2016 - 2018 Immunological assay for development of a novel treatment guideline in malignant melanoma
2015 - 2018 Development of novel treatments of myeloma based on MRD using next-generation sequencing and protein-array assay

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Papers (224)：

Wenhao Zhou, Shusuke Kawashima, Takamasa Ishino, Katsushige Kawase, Youki Ueda, Kazuo Yamashita, Tomofumi Watanabe, Masahito Kawazu, Hiromichi Dansako, Yutaka Suzuki, et al. Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment. Cell reports. 2024. 43. 2. 113797-113797
Hiroaki Hiramatsu, Rui Yokomori, Liu Shengyi, Norio Tanaka, Seiichi Mori, Kazuma Kiyotani, Osamu Gotoh, Shigeru Kusumoto, Nobuaki Nakano, Youko Suehiro, et al. Clinical landscape of TP73 structural variants in ATL patients. Leukemia. 2023
Hitomi S Okuma, Keisuke Watanabe, Kenji Tsuchihashi, Ryunosuke Machida, Ryo Sadachi, Akihiro Hirakawa, Hiroshi Ariyama, Masashi Kanai, Masahisa Kamikura, Kenta Anjo, et al. Phase 2 trial of nivolumab in metastatic rare cancer with dMMR or MSI-H and relation with immune phenotypic analysis (the ROCK trial). Clinical cancer research : an official journal of the American Association for Cancer Research. 2023
Masaaki Ito, Shintaro Iwama, Daisuke Sugiyama, Yoshinori Yasuda, Takayuki Okuji, Tomoko Kobayashi, Xin Zhou, Ayana Yamagami, Takeshi Onoue, Takashi Miyata, et al. Anti-tumor effects of anti-programmed cell death-1 antibody treatment are attenuated in streptozotocin-induced diabetic mice. Scientific reports. 2023. 13. 1. 5939-5939
Akihito Harusato, Wooseok Seo, Hirohito Abo, Yoshitaka Nakanishi, Hiroyoshi Nishikawa, Yoshito Itoh. Impact of particulate microplastics generated from polyethylene terephthalate on gut pathology and immune microenvironments. iScience. 2023. 26. 4. 106474-106474

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MISC (115)：

Takuya Owari, Shohei Koyama, Hiroyoshi Nishikawa. 解説_がん免疫療法バイオマーカー研究の進展. 2023. 31. 3. 375-380
熊谷尚悟, 小山正平, 板橋耕太, 冨樫庸介, 吉田達哉, 石井源一郎, 河津正人, 山崎直也, 坪井正博, 谷田部恭, et al. 腫瘍微小環境における制御性T細胞に特徴的な代謝学的チェックポイントの同定(Identification of a distinctive metabolic checkpoint of regulatory T cells in the tumor microenvironment). 日本癌学会総会記事. 2022. 81回. CES1-3
小山正平, 西川博嘉. 【がん免疫療法研究の進歩】がん免疫応答を制御する免疫細胞の解明制御性T細胞による免疫応答調節. 腫瘍内科. 2022. 29. 2. 168-172
種子島時祥, 小山正平, 西川博嘉. 【夜明けを迎えたヒト免疫学臨床検体からヒトの免疫応答機構の実態を知り、疾患制御に挑む】ヒトがん免疫療法の発展と課題 CD8+ T細胞からの視点. 実験医学. 2022. 40. 1. 15-20
塚田祐一郎, 坂東英明, 稲守宏冶, 冨樫庸介, 結城敏志, 小松嘉人, 本間重紀, 武冨紹信, 植村守, 加藤健志, et al. 大腸癌周術期治療の臨床開発と将来展望進行直腸癌に対する化学放射線療法と免疫チェックポイント阻害剤を用いた術前治療. 日本癌治療学会学術集会抄録集. 2021. 59回. SY2-4

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Patents (7)：

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Books (5)：

実験医学 2018年6月 Vol.36 No.9 がんは免疫系をいかに抑制するのか〜免疫チェックポイント阻害剤の真の標的を求めて
羊土社 2018 ISBN:4758125082
がん免疫療法-What's now and what's next?-(遺伝子医学MOOK31号)
メディカルドゥ 2017 ISBN:9784944157617
がん免疫療法ハンドブック
メディカルレビュー社 2016 ISBN:9784779217166
がん免疫療法のメカニズム解明と臨床への展開がんと免疫 (The Frontiers in Life Sciences)
南山堂 2015 ISBN:4525134712
がんと免疫 : がん免疫療法のメカニズム解明と臨床への展開
南山堂 2015 ISBN:9784525134716

Education (2)：

1998 - 2002 Mie University
1995 - Mie University Faculty of Medicine School of Medecine

Professional career (1)：

医学博士

Work history (12)：

2021/04 - 現在糖鎖生命コア研究所機能制御分野教授
2016 - 現在 Nagoya University Graduate School of Medicine
2015 - 現在国立がん研究センター先端医療開発センター免疫トランスレーショナルリサーチ分野分野長
2015 - 現在国立がん研究センター研究所腫瘍免疫分野分野長
2012 - 2015 Department of Oncology Roswell Park Cancer Institute Adjunct Associate Professor

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