Rchr
J-GLOBAL ID:201001017266057899   Update date: Nov. 20, 2024

Hirokazu Yagi

ヤギ ヒロカズ | Hirokazu Yagi
Affiliation and department:
Homepage URL  (1): http://www.phar.nagoya-cu.ac.jp/hp/mfa/
Research field  (7): Functional biochemistry ,  Structural biochemistry ,  Molecular biology ,  Cell biology ,  Pharmaceuticals - analytical and physicochemistry ,  Pharmacology ,  Pharmaceuticals - health and biochemistry
Research keywords  (6): biopharmaceuticals ,  細胞生物学 ,  蛋白質科学 ,  糖鎖生物学 ,  Neuroscience ,  Glycobiology
Research theme for competitive and other funds  (27):
  • 2023 - 2026 老化時計リバイバル機構の解明 -老化研究における新たなパラダイムシフトの総括
  • 2023 - 2026 Development and application of multi-omics analysis for elucidating the revival mechanism of aging clock
  • 2022 - 2026 An extedned research of cell membrane domains based on the probes of membrane molecules
  • 2022 - 2026 Group A Streptococcus glycoproteins evade immune defense mechanisms
  • 2023 - 2026 タンパク質に組み込まれた糖鎖修飾コードの解明と糖鎖修飾制御
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Papers (139):
  • Satoshi Nakagawa, Hiroyuki D Sakai, Shigeru Shimamura, Yoshiki Takamatsu, Shingo Kato, Hirokazu Yagi, Saeko Yanaka, Maho Yagi-Utsumi, Norio Kurosawa, Moriya Ohkuma, et al. N-linked protein glycosylation in Nanobdellati (formerly DPANN) archaea and their hosts. Journal of bacteriology. 2024. e0020524
  • Tadashi Satoh, Maho Yagi-Utsumi, Nozomi Ishii, Tsunehiro Mizushima, Hirokazu Yagi, Ryuichi Kato, Yuriko Tachida, Hiroaki Tateno, Ichiro Matsuo, Koichi Kato, et al. Structural basis of sugar recognition by SCFFBS2 ubiquitin ligase involved in NGLY1 deficiency. FEBS letters. 2024
  • Kiyoko F Aoki-Kinoshita, Hiromune Ando, Kiyohiko Angata, Morihisa Fujita, Jun-Ichi Furukawa, Hiroyuki Kaji, Koichi Kato, Ken Kitajima, Yasuhiko Kizuka, Yusuke Matsui, et al. The Human Glycome Atlas Project for cataloging all glycan-related omics data in human. Glycobiology. 2024
  • Marietta Fabiano, Naoto Oikawa, Anja Kerksiek, Jun-ichi Furukawa, Hirokazu Yagi, Koichi Kato, Ulrich Schweizer, Wim Annaert, Jongkyun Kang, Jie Shen, et al. Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function. International Journal of Molecular Sciences. 2024. 25. 10. 5417-5417
  • Saeko Yanaka, Atsuji Kodama, Shigetaka Nishiguchi, Rina Hiramine, Jiana Shen, Pornthip Boonsri, Duckyong Sung, Yukiko Isono, Hirokazu Yagi, Yohei Miyanoiri, et al. Identification of potential C1-binding sites in the immunoglobulin CL domains. International Immunology. 2024
more...
MISC (83):
  • 大下修一郎, 山代萌, 矢木宏和, 矢木宏和, LIEW Chia-Yen, NI Chi-Kung, 加藤晃一, 加藤晃一, 加藤晃一, 蜷川暁, et al. Functional analysis of Golgi-localized mannosidase MAN1B1. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • 保科明, 矢木宏和, 矢木宏和, 矢木真穂, 矢木真穂, 石川怜, 肥田重明, 加藤晃一, 加藤晃一. Exploration of the mechanisms underlying matriglycan elongation during T cell differentiation. 日本薬学会年会要旨集(Web). 2023. 143rd
  • 蜷川暁, 蜷川暁, 松尾將生, DENG Ying, 阿曽伸哉, 松下和俊, 笛木茜, 斎藤俊介, 今見考志, 木塚康彦, et al. UGGTs prevent premature degradation of unstable and misfolded glycoproteins in the endoplasmic reticulum. 日本糖質学会年会要旨集. 2023. 42nd
  • 松尾將生, DENG Ying, 矢木宏和, 矢木宏和, 津曲和哉, 笛木茜, 今見考志, 加藤晃一, 加藤晃一, 加藤晃一, et al. UGGTs affect not only glycoprotein folding but also degradation. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • 中川聡, 中川聡, 中川聡, 島村繁, 高松芳基, 酒井博之, 加藤真悟, 澤山茂樹, 矢木宏和, 矢木宏和, et al. Protein glycosylation in DPANN archaea and their host archaea. 日本微生物生態学会大会(Web). 2023. 36th
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Patents (4):
Books (11):
  • 糖鎖生物学 : 生命現象と糖鎖情報(北島健,佐藤ちひろ,門松健治,加藤晃一編)
    名古屋大学出版会 2020
  • 医薬品/化粧品/食品分野におけるHPLC・GC分析テクニック
    技術情報協会 2020
  • 医薬品開発における創薬スクリーニング関連技術開発
    情報機構 2019 ISBN:9784865021806
  • Modern Magnetic Resonance, 2nd Edition (G.A.Webb ed.), NMR characterization of the dynamic conformations of oligosaccharides
    Springer International Publishing 2018
  • Glycobiophysics (Y.Yamaguchi and K.Kato ed.), Structure and dynamics of immunoglobulin G glycoproteins
    Springer Nature Singapore 2018
more...
Lectures and oral presentations  (23):
  • 糖転移酵素によるタンパク質特異的な糖鎖修飾機構
    (第93回日本生化学会大会 2020)
  • 積荷受容体が認識するパスポート配列タグの付加に伴うα2,3シアリル化の亢進
    (第42回 日本分子生物学会年会 2019)
  • The molecular mechanisms underlying protein-specific glycosylation
    (Invited Seminar at UGSF 2019)
  • Structural characterization of the circadian clock protein complexes composed of KaiA, KaiB and KaiC by integrative structural approaches
    (第3回 J-PARC国際シンポジウム 2019)
  • Molecular mechanisms underlying protein-specific glycosylation pattern formation by tagging with a MCFD2-binding motif sequence recognized by cargo receptor
    (第92回 日本生化学会大会 2019)
more...
Education (3):
  • 2005 - 2008 Nagoya City University Graduate School of Pharmaceutical Sciences
  • 2003 - 2005 Nagoya City University Graduate School of Pharmaceutical Sciences
  • 1999 - 2003 Nagoya City University Medicin Medicin
Professional career (1):
  • 博士(薬学) (名古屋市立大学大学院薬学研究科)
Work history (6):
  • 2023/04 - 現在 Nagoya City University Graduate School of Pharmaceutical Sciences Department of Multilevel Biofunctional Analytics Associate professor
  • 2021/10 - 現在 Nagoya City University
  • 2013/10 - 現在 Nagoya City University Graduate School of Pharmaceutical Sciences
  • 2009/06 - 2013/09 名古屋市立大学 薬学研究科(研究院) 助教
  • 2009/04 - 2009/06 National Institutes of Natural Sciences
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Committee career (7):
  • 2024/09 - 現在 The Journal of Biochemistry Associate editor
  • 2023/09 - 現在 Frontiers in Molecular Biosciences Associate editor
  • 2023/09 - 現在 FCCA 幹事
  • 2023/09 - 現在 日本生化学会 評議員
  • 2023/07 - 現在 日本糖質学会 評議員
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Awards (5):
  • 2018/09 - 日本生化学会奨励賞
  • 2017/09 - 日本バイオイメージング学会奨励賞
  • 2015/08 - 日本糖質学会奨励賞
  • 2015/08 - 名古屋市立大学大学院薬学研究科長表彰
  • 2013/08 - 日本糖質学会ポスター賞受賞
Association Membership(s) (6):
BIOIMAGING SOCIETY ,  JAPAN SOCIETY FOR CELL BIOLOGY ,  PROTEIN SCIENCE SOCIETY OF JAPAN ,  日本薬学会 ,  日本糖質学会 ,  日本生化学会
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