Research field (4):
Laboratory animal science
, Neuroanatomy and physiology
, Neuroscience - general
, Animals: biochemistry, physiology, behavioral science
Research theme for competitive and other funds (8):
2022 - 2026 アトピー性皮膚炎の増悪に関わる脳内メカニズムの解明
2022 - 2024 系統差から見出す痒みの個体差の遺伝的基盤
2019 - 2021 痒み中枢細胞制御による眼の痒み誘発および治療モデル動物の開発
2016 - 2018 痒みを特異的に伝達する脳-脊髄神経ネットワークの同定(国際研究強化)
2015 - 2017 系統進化学的アプローチによる痒み感覚の獲得およびその生理機能の統合解明
2014 - 2015 痒みを特異的に伝達する脳-脊髄神経ネットワークの同定
2012 - 2013 感覚神経を標的としたホルモン制御による中枢性鎮痒薬の探索
2011 - 2012 エストロゲンによる痒み調節機構の解明
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Papers (35):
Keiko Takanami, Masaya Kuroiwa, Ren Ishikawa, Yuji Imai, Akane Oishi, Midori Hashino, Yasushi Shimoda, Hirotaka Sakamoto, Tsuyoshi Koide. Function of gastrin-releasing peptide receptors in ocular itch transmission in the mouse trigeminal sensory system. Frontiers in Molecular Neuroscience. 2023. 16. 1280024
Keiko Takanami, Makoto Morishita, Tatsuya Sakamoto, Hirotaka Sakamoto. Chronic corticosterone exposure evokes itch hypersensitivity and sexual dysfunction in male rats: Relationship between the two distinct gastrin-releasing peptide systems in the spinal cord. General and Comparative Endocrinology. 2023. 339. 114289-114289
Keiko Takanami. Gastrin-Releasing Peptide and Gastrin-Releasing Peptide Receptor Expressing Neurons (Chapter 5). Histaminergic and non-histaminergic itch: From channels to behavior. Nova science publishers. 2023. 93-108
Keiko Takanami, Takumi Oti, Yasuhisa Kobayashi, Koki Hasegawa, Takashi Ito, Naoaki Tsutsui, Yasumasa Ueda, Earl Carstens, Tatsuya Sakamoto, Hirotaka Sakamoto. Characterization of the expression of gastrin-releasing peptide and its receptor in the trigeminal and spinal somatosensory systems of Japanese macaque monkeys: Insight into humans. Journal of Comparative Neurology. 2022. 530. 16. 2804-2819
Yukitoshi Katayama, Ayane Miura, Tatsuya Sakamoto, Keiko Takanami, Hirotaka Sakamoto. Footedness for scratching itchy eyes in rodents. Proceedings of the Royal Society B: Biological Sciences. 2022. 289. 1985. 20221126-20221126