Rchr
J-GLOBAL ID:201001021878999424   Update date: Jul. 30, 2024

Shinichiro Kina

キナ シンイチロウ | Shinichiro Kina
Affiliation and department:
Research field  (1): Molecular biology
Research keywords  (6): 活性酸素 ,  組織学的分化度 ,  メトロノーム化学療法 ,  癌 ,  高分化型腫瘍 ,  炎症
Research theme for competitive and other funds  (7):
  • 2024 - 2027 Wnt 経路を介した組織学的分化度依存的に生じる腫瘍血管形成機構の解明
  • 2021 - 2024 EphA4活性化により生じる高分化型口腔癌メトロノーム化学療法耐性機構の解明
  • 2020 - 2023 古典型カポジ肉腫の自然消退のメカニズムの解明と治療への応用について
  • 2018 - 2020 抗癌剤耐性高分化型口腔癌に対するEphA4を標的とした分子生学的メカニズムの解明
  • 2017 - 2019 抗癌剤曝露依存的に活性化されるEphA4 を標的とした新規治療戦略の構築
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Papers (28):
  • Shinichiro Kina, Sho Miyamoto, Reika Kawabata-Iwakawa, Mika Kina-Tanada, Masaru Ogawa, Satoshi Yokoo. Higher overall survival rates of oral squamous cell carcinoma treated with metronomic neoadjuvant chemotherapy. American Journal of Cancer Research. 2024. 14. 3. 1033-1051
  • Sho Miyamoto, Yoshihiko Hirohashi, Rena Morita, Akihiro Miyazaki, Kazuhiro Ogi, Takayuki Kanaseki, Kentaro Ide, Jumpei Shirakawa, Tomohide Tsukahara, Aiko Murai, et al. Exploring olfactory receptor family 7 subfamily C member 1 as a novel oral cancer stem cell target for immunotherapy. Cancer science. 2023. 114. 9. 3496-3508
  • Shinichiro Kina, Reika Kawabata-Iwakawa, Sho Miyamoto, Tomoki Kato, Mika Kina-Tanada, Akira Arasaki. EphA4 signaling is involved in the phenotype of well-differentiated oral squamous cell arcinoma with decreased tumor immunity. European journal of pharmacology. 2023. 945. 175611-175611
  • Akiyuki Sugisawa, Zensei Toyoda, Yasuka Tanabe, Karina Uehara, Aya Oshiro, Reo Yamazato, Chiharu Sakamoto, Shohei Yogi, Kiyoto Kurima, Shinichiro Kina, et al. Cytological characteristics of premalignant cervical epithelial lesions in postmenopausal women based on endocrine indices and parakeratosis. Menopause. 2022. 30. 2. 193-200
  • Karina Uehara, Yasuka Tanabe, Shintaro Hirota, Saki Higa, Zensei Toyoda, Kiyoto Kurima, Shinichiro Kina, Toshiyuki Nakasone, Akira Arasaki, Takao Kinjo. Co-expression of low-risk HPV E6/E7 and EBV LMP-1 leads to precancerous lesions by DNA damage. BMC Cancer. 2021. in press
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MISC (3):
Lectures and oral presentations  (1):
  • 高分化型口腔扁平上皮癌が有するメトロノーム化学療法耐性機構の解明
    (第40回日本口腔腫瘍学会総会・学術大会 2022)
Work history (4):
  • 2010/04/01 - - , 琉球大学 医学研究科 助教
  • 2010/04/01 - - , University of the Ryukyus, Graduate School of Medicine, Research Associate
  • Gunma University Lecturer
  • University of the Ryukyus Graduate School of Medicine Instructor
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