Rchr
J-GLOBAL ID:201001039222668800
Update date: Nov. 16, 2024
Uwada Junsuke
ウワダ ジュンスケ | Uwada Junsuke
Affiliation and department:
Kanazawa Medical University Department of Pharmacology, School of Medicine
About Kanazawa Medical University Department of Pharmacology, School of Medicine
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Detailed information
Research field (1):
Pharmacology
Research keywords (2):
G protein-coupled receptor
, post-translational modification
Research theme for competitive and other funds (14):
2022 - 2025 蛍光アセチルコリンセンサーによる細胞内コリン伝達系の実証
2019 - 2023 Induction of steroidogenic cells from stem cells based on the regulation of LRH-1 expression
2018 - 2021 Reinforcement of colonic epithelial barrier via mAChR
2019 - 2021 細胞内局在性ムスカリン受容体の生体における機能解析
2016 - 2019 Functional role of intracellular muscarinic receptor for hippocampal adult neurogenesis
2015 - 2018 Induction of ovarian granulosa cells from mesenchymal stem cells for investigating the molecular mechanisms of their development.
2014 - 2016 Evaluation of intracellular GPCR activation by using FRET imaging
2013 - 2016 Maintenance of intestinal barrier function by focal adhesion kinase
2012 - 2015 Novel functions of surface and intracellular muscarinic receptors in central nervous system and stress
2009 - 2011 Analysis for protein SUMOylation in the central synaptic proteins
2009 - 2010 脳スライスからの高感度神経伝達物質遊離測定法の開発と中枢神経薬理学への応用
2008 - 2010 Receptor-operated Ca influx and transmitter release
2010 - α1L型アドレナリン受容体形成の分子機構解明
2010 - Molecular mechanism of a1L adrenoceptor formation
Show all
Papers (54):
Takeshi Kiyoi, Qiang He, Li Liu, Shijie Zheng, Hitomi Nakazawa, Junsuke Uwada, Takayoshi Masuoka. Morphological aberration of corneal nerves in hyposecretory dry eye guinea pigs. Medical molecular morphology. 2024
Takayoshi Masuoka, Takeshi Kiyoi, Shijie Zheng, Qiang He, Li Liu, Junsuke Uwada, Ikunobu Muramatsu. Corneal acetylcholine regulates sensory nerve activity via nicotinic receptors. The ocular surface. 2024. 32. 60-70
Ikunobu Muramatsu, Junsuke Uwada, Takayoshi Masuoka. Tissue-Segment Binding Method for Detection of Muscarinic Acetylcholine Receptors in Receptor’s Natural Environment. Neuromethods. 2024. 211. 33-42
Ikunobu Muramatsu, Itsumi Arakawa, Junsuke Uwada, Noriyuki Matsukawa, Takayoshi Masuoka. Evaluation of Acetylcholine Synthesis and Release in Striatal Cholinergic Interneurons. Neuromethods. 2024. 211. 269-279
Itsumi Arakawa, Ikunobu Muramatsu, Junsuke Uwada, Kiyonao Sada, Noriyuki Matsukawa, Takayoshi Masuoka. Acetylcholine release from striatal cholinergic interneurons is controlled differently depending on the firing pattern. Journal of neurochemistry. 2023. 167. 1. 38-51
more...
MISC (9):
Takashi Yazawa, Yoshitaka Imamichi, Toshio Sekiguchi, Kaoru Miyamoto, Junsuke Uwada, Md Rafiqul Islam Khan, Nobuo Suzuki, Akihiro Umezawa, Takanobu Taniguchi. Transcriptional Regulation of Ovarian Steroidogenic Genes: Recent Findings Obtained from Stem Cell-Derived Steroidogenic Cells. BioMed Research International. 2019. 2019
宇和田 淳介, 矢澤 隆志, 谷口 隆信. 腸上皮細胞におけるムスカリン受容体のストア作動性カルシウム流入を介したp38MAPキナーゼ制御. 日本生化学会大会プログラム・講演要旨集. 2018. 91回. [2P-186]
矢澤 隆志, 今道 力敬, 宮本 薫, 宇和田 淳介, 谷口 隆信. DES投与が幼若ラット卵巣のステロイドホルモン合成に及ぼす影響の解析. 日本内分泌学会雑誌. 2018. 94. 1. 320-320
Takashi Yazawa, Yoshitaka Imamichi, Kaoru Miyamoto, Md Raiqul Islam Khan, Junsuke Uwada, Akihiro Umezawa, Takanobu Taniguchi. Induction of steroidogenic cells from adult stem cells and pluripotent stem cells. Endocrine Journal. 2016. 63. 11. 943-951
A. Nishimune, H. Yoshiki, J. Uwada, A. S.M. Anisuzzaman, H. Umada, I. Muramatsu. Phenotype pharmacology of lower urinary tract α
1
- adrenoceptors. British Journal of Pharmacology. 2012. 165. 5. 1226-1234
more...
Lectures and oral presentations (12):
Influence of anticancer drug S-1 on ocular surface with histological alterations of corneal nerve in rat
(2023)
Regulation of trigeminal ganglion neurons innervating cornea by acetylcholine receptors.
(2023)
プロベネシドが3次元培養された前立腺がん細胞に与える多様な効果
(第96回日本薬理学会年会 2022)
細胞内局在性GPCR活性化のリアルタイム観察
(第24回活性アミンに関するワークショップ 2022)
涙腺摘出による慢性的眼乾燥状態はうつ様行動を誘発する。
(第95回日本薬理学会年会 2022)
more...
Works (4):
成育初期ストレスによる精神的発達障害のメカニズム-ムスカリン受容体の新しい機能, 基盤研究(C)(一般)
2013 -
シナプス構成タンパク質のSUMO化ファルマコームの解明, 基盤研究(C)(一般)
2011 -
受容体作動性Caイオン流入機構の分子メカニズムと中枢神経伝達物質遊離機序, 基盤研究(B)(一般)
2010 -
脳スライスからの高感度神経伝達物質遊離測定法の開発と中枢神経薬理学への応用, 挑戦的萌芽研究
2010 -
Education (3):
- 2010 Kumamoto University
- 2007 Kumamoto University
- 2004 University of Miyazaki Faculty of Agriculture Department of Biochemistry and Applied Biosciences
Professional career (2):
理学博士 (熊本大学)
医学修士 (熊本大学)
Work history (4):
2021/09 - 現在 Kanazawa Medical University
2014/12 - 2021/08 Asahikawa Medical University
2014/04 - 2014/12 Kobe University Biosignal Research Center
2010/04 - 2014/03 University of Fukui Faculty of Medical Sciences Assistant Professor
Association Membership(s) (5):
日本薬理学会
, 日本分子生物学会
, 日本エピジェネティクス研究会
, SUMO研究会
, 日本生化学会
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