Rchr
J-GLOBAL ID:201001052276951547   Update date: Nov. 04, 2024

Waki Hironori

ワキ ヒロノリ | Waki Hironori
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://www.med.akita-u.ac.jp/~rounen/index.html
Research field  (5): Nutrition and health science ,  Metabolism and endocrinology ,  Cell biology ,  Molecular biology ,  Genetics
Research keywords  (19): Transcriptional regulation ,  Metabolic Syndrome ,  Adipokine ,  Brown adipocytes ,  Obesity ,  gene transcription ,  High throughput sequencing ,  ChIP-seq ,  FAIRE-seq ,  Regulatory elements ,  Open chromatin ,  Diabetes ,  Differentiation ,  Genome ,  Epigenetics ,  Epigenome ,  Chromatin ,  Nuclear receptor ,  Adipocytes
Research theme for competitive and other funds  (27):
  • 2023 - 2024 糖尿病の実態把握と発症予防・重症化予防のための研究
  • 2020 - 2024 Role of NFIA in systemic metabolism and energy balance
  • 2021 - 2023 Epigenetic Regulation of Adipocyte Progenitor Cells
  • 2021 - 2023 NFIAを標的としたヒト肥満治療法開発のための研究展開
  • 2019 - 2022 Study on reduction of risk factors for life-style related diseases through activating brown and white adipose tissue by nutrition, exercise, and cold exposure
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Papers (83):
  • Sanil Patel, Khatanzul Ganbold, Chung Hwan Cho, Juwairriyyah Siddiqui, Ramazan Yildiz, Njeri Sparman, Shani Sadeh, Christy M Nguyen, Jiexin Wang, Julian P Whitelegge, et al. Transcription factor PATZ1 promotes adipogenesis by controlling promoter regulatory loci of adipogenic factors. Nature communications. 2024. 15. 1. 8533-8533
  • Kayo Waki, Yuya Tsurutani, Hironori Waki, Syunpei Enomoto, Kosuke Kashiwabara, Akira Fujiwara, Kazuki Orime, Sho Kinguchi, Toshimasa Yamauchi, Nobuhito Hirawa, et al. Efficacy of StepAdd, a Personalized mHealth Intervention Based on Social Cognitive Theory to Increase Physical Activity Among Patients With Type 2 Diabetes Mellitus: Protocol for a Randomized Controlled Trial. JMIR research protocols. 2024. 13. e53514
  • Hanako Toyama, Kazuyuki Takahashi, Tatsunori Shimizu, Izumi Otaka, Sakiko Abe, Shunsuke Kato, Sayaka Ando, Takehiro Sato, Tsukasa Morii, Hiroki Fujita, et al. Recurrent nocturnal hypoglycemic hemiplegia: a case report and review of the literature. Endocrine journal. 2024
  • Yuya Takahashi, Hiroki Fujita, Yusuke Seino, Satoko Hattori, Shihomi Hidaka, Tsuyoshi Miyakawa, Atsushi Suzuki, Hironori Waki, Daisuke Yabe, Yutaka Seino, et al. Gastric inhibitory polypeptide receptor antagonism suppresses intramuscular adipose tissue accumulation and ameliorates sarcopenia. Journal of cachexia, sarcopenia and muscle. 2023
  • Yuta Hiraike, Kaede Saito, Misato Oguchi, Takahito Wada, Gotaro Toda, Shuichi Tsutsumi, Kana Bando, Junji Sagawa, Gaku Nagano, Haruya Ohno, et al. NFIA in adipocytes reciprocally regulates mitochondrial and inflammatory gene program to improve glucose homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 31. e2308750120
more...
MISC (161):
  • 松田 大輔, 岩村 庄吾, 本郷 真伊, 奈良 藍子, 阿部 咲子, 保泉 学, 大友 瞳, 佐々木 可奈, 加藤 俊祐, 脇 裕典. 糖尿病合併脂質異常症へのPemafibrateの脂質,肝線維化マーカーへの影響の検討(第2報). 日本内科学会雑誌. 2024. 113. 臨増. 181-181
  • 松田 大輔, 岩村 庄吾, 本郷 真伊, 田近 武伸, 奈良 藍子, 小木田 彩香, 奥山 慎, 高橋 和之, 加藤 俊祐, 脇 裕典. 糖尿病腎臓病に対するFinerenoneの腎機能に与える影響の後ろ向き研究. 日本内科学会雑誌. 2024. 113. 臨増. 182-182
  • 高橋侑也, 藤田浩樹, 脇裕典, 山田祐一郎, 山田祐一郎. GIPによる骨格筋間葉系前駆細胞の脂肪分化制御とサルコペニアとの関連. 日本内分泌学会雑誌. 2024. 100. 1
  • 戸田郷太郎, 升田紫, 神野康介, 亀田紗緒里, 劉念東, 陳誉天, 大口弥里, 斎藤楓, 平池勇雄, 正本庸介, et al. 門脈内短鎖脂肪酸は免疫細胞の蛋白分解を促進し食後のインスリン作用を維持する. 日本内分泌学会雑誌. 2024. 100. 1
  • 加藤俊祐, 加藤俊祐, 赤沼英, 奈良光彦, 清水辰徳, 清水辰徳, 佐藤雄大, 森井宰, 藤田浩樹, 脇裕典. コルチゾール測定法の変更に伴う副腎不全の診断率の変化とカットオフ値の検討. 日本内分泌学会雑誌. 2024. 100. 1
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Books (18):
  • Brown Adipose Tissue: Science and Applications
    CMC Publishing CO.,LTD. 2024 ISBN:9784781318035
  • Today's treatment guide 2024
    Igaku-shoin Ltd. Tokyo 2024 ISBN:9784260053426
  • Pharmacological approach to treat diabetes mellitus
    2023 ISBN:9784784903740
  • 糖尿病学2023
    診断と治療社 2023 ISBN:9784787825933
  • Big data and medicine
    2023
more...
Lectures and oral presentations  (104):
  • Epigenetic Regulation of Brown-Fat-Specific Genes by Nuclear Factor I-A and Its Role in Energy Homeostasis
    (Korean Society for Biochemistry and Molecular Biology (KSBMB) International Conference 2024, Symposium 4, Pioneering Mouse Model Studies for Metabolic and Endocrine Disorders 2024)
  • Regulation of energy metabolism by adipocyte NFIA and the role of the epigenome
    (The 67th Annual Meeting of the Japanese Diabetes Society, Symposium 24 New Developments in Brown, Beige, and White Adipocytes 2024)
  • Experience from Japan - Earthquakes and floods, Symposium, Diabetes care during natural disasters - Experiences from affected countries
    (IDF congress 2023 2023)
  • The epigenome of adipocytes and energy homeostasis
    (The 44th Annual Meeting of Japan Society for the Study of Obesity (JASSO 44) / The 41st Annual Meeting of the Japanese Society for Treatment of Obesity (JSTO 41) 2023)
  • よく知って上手につきあう肥満と糖尿病 ~最近のトピックス~
    (第48回地域の医療を考える集い 2023)
more...
Professional career (1):
  • MD, PhD (The University of Tokyo)
Work history (15):
  • 2021/06 - 現在 Department of Metabolism and Endocrinology, Akita University Graduate School of Medicine Professor
  • 2019/09 - 2021/05 Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo Associate Professor
  • 2018/11 - 2019/08 Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo Lecturer
  • 2016/09 - 2018/10 Department of Molecular Sciences on Diabetes, Graduate School of Medicine, the University of Tokyo Project Associate Professor
  • 2016/04 - 2016/08 Department of Diabetes and Metabolic Diseases, the University of Tokyo Hospital Assistant Professor
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Committee career (41):
  • 2024/04 - 現在 Akita Univeristy Hospital Deputy Hospital Director
  • 2024/04 - 現在 Japan Association for Diabetes Education and Care Deligate
  • 2024/03 - 現在 The Japan Society for the Study of Obesity Auditor, controller
  • 2024/03 - 現在 Japan Society for the Study of Obesity Chair of Young Committee
  • 2024/03 - 現在 Japan Society for the Study of Obesity Education Committee Members
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Awards (7):
  • 2017/10 - The Japan Society of Diabetic Complications Young Investigator Award Transcriptional and epigenetic regulation in adipocytes and its significance in glucose, lipid and energy homeostasis
  • 2017/09 - The Japanese Constitutional Medicine Society Award Transcriptional and epigenetic regulation in adipocytes and its significance in life-style diseases
  • 2015/11 - The Japan Medical Association Medical Research Encouragement Prize of The Japan Medical Association
  • 2015/07 - Japan Association for Diabetes Education and Care William Cullen Award
  • 2013/10 - Japan Society for the Study of Obesity Encouragement Prize for Obesity Research The role of transcriptional and epigenetic regulation in adipocytes
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Association Membership(s) (11):
The Japan Society of Diabetic Complications ,  The Japanese Constitutinal Medicine ,  Japanese Society for Treatment of Obesity ,  Japan Society of Metabolism and Clinical Nutrition ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  JAPAN SOCIETY FOR THE STUDY OF OBESITY ,  THE JAPAN ENDOCRINE SOCIETY ,  THE JANPANESE SOCIETY OF INTERNAL MEDICINE ,  JAPAN DIABETES SOCIETY ,  The Japan Geriatrics Society ,  American Diabetes Association
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