Rchr
J-GLOBAL ID：201001054996991204   Update date: Jan. 30, 2024

Kushiro Tetsuo

クシロ テツオ | Kushiro Tetsuo
Affiliation and department：
Meiji University School of Agriculture

About Meiji University School of Agriculture


Job title： Professor
Research field  (1)： Bioorganic chemistry
Research theme for competitive and other funds  (14)：
  • 2021 - 2024 Functional analysis of novel aminoacyl-sterol derivatives in fungi
  • 2014 - 2019 環境応答機能の解明 に基づく高度環境適応植物デザイン研究基盤の確立
  • 2012 - 2016 機能性成分の生合成遺伝子マーカーの探索
  • 2011 - 2015 Enzyme engineering for natural product biosynthesis
  • 2011 - 2014 ステロイド類生合成修飾酵素を活用した有用物質生産系の構築
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Papers (60)：
  • Nathaniel Yakobov, Nassira Mahmoudi, Guillaume Grob, Daisuke Yokokawa, Yusuke Saga, Tetsuo Kushiro, Danielle Worrell, Hervé Roy, Hubert Schaller, Bruno Senger, et al. RNA-dependent synthesis of ergosteryl-3β-O-glycine in Ascomycota expands the diversity of steryl-amino acids. Journal of Biological Chemistry. 2022. 298. 3. 101657-101657
  • Daisuke Yokokawa, Shunsuke Tatematsu, Ryoka Takagi, Yusuke Saga, Hervé Roy, Frédéric Fischer, Hubert D. Becker, Tetsuo Kushiro. Synthesis of aminoacylated ergosterols: A new lipid component of fungi. Steroids. 2021. 169. 108823-108823
  • Shingo Naraki, Mai Kakihara, Sayuri Kato, Yusuke Saga, Kazuto Mannen, Shohei Takase, Akihito Takano, Sayaka Shinpo, Tsutomu Hosouchi, Takahisa Nakane, et al. Two Triterpene Synthases from Imperata cylindrica Catalyzing the Formation of a Pair of Diastereoisomers through Boat or Chair Cyclization. ChemBioChem. 2021. 22. 11. 1992-2001
  • Yusuke Saga, Moeka Kawashima, Shiho Sakai, Kaori Yamazaki, Misato Kaneko, Moeka Takahashi, Natsuko Sato, Yohei Toyoda, Shohei Takase, Takeshi Nakano, et al. Plant-Specific Domains and Fragmented Sequences Imply Non-Canonical Functions in Plant Aminoacyl-tRNA Synthetases. Genes. 2020. 11. 9. 1056-1056
  • Nathaniel Yakobov, Frédéric Fischer, Nassira Mahmoudi, Yusuke Saga, Christopher D. Grube, Hervé Roy, Bruno Senger, Guillaume Grob, Shunsuke Tatematsu, Daisuke Yokokawa, et al. RNA-dependent sterol aspartylation in fungi. Proceedings of the National Academy of Sciences. 2020. 117. 26. 14948-14957
ｍore...
MISC (7)：
  • 大山清, 鈴木優志, TING Xiang, 關光, 菊地淳, 久城哲夫, 渋谷雅明, 海老塚豊, 斉藤和季, 村中俊哉. ラノステロールを経由する植物ステロール新規生合成経路. 天然有機化合物討論会講演要旨集. 2007. 49th. 37-42
  • Mitsuguchi Hisashi, Nomura Takahito, Kamiya Yuji, Yamaguchi Shinjiro, Ebizuka Yutaka, Kushiro Tetsuo. 57. Functional analysis of CYP85A family involved in brassinolide biosynthesis. The Janapese Society for Chemical Regulation of Plants, Abstract. 2007. 42. 70-70
  • M Okamoto, A Kuwahara, T Kushiro, Y Kamiya, T Koshiba, E Nambara. Physiological roles of ABA 8 '-hydroxylase family, key enzymes in ABA catabolism during seed development through to postgermination growth in Arabidopsis thaliana. PLANT AND CELL PHYSIOLOGY. 2006. 47. S147-S147
  • T Nomura, T Kushiro, T Yokota, Y Kamiya, G Bishop, S Yamaguchi. Identification of a cytochrorne P450 nionooxygenase that produces brassinolide, the most active brassinosteroid. PLANT AND CELL PHYSIOLOGY. 2005. 46. S49-S49
  • M Okamoto, T Kushiro, T Asami, T Koshiba, Y Kamiya, E Nambara. Physiological role of ABA 8 '-hydroxylase family, key enzymes in ABA catabolism in Arabidopsis thaliana. PLANT AND CELL PHYSIOLOGY. 2005. 46. S50-S50
ｍore...
Books (7)：
  • Reconstitution of a secondary metabolite biosynthetic pathway in a heterologous fungal host.
    Springler 2012
  • Triterpenes
    Elsevier: Oxford 2010
  • 生薬学へのいざない? 生薬学は今日の医療にどう役立つのか?
    京都廣川書店 2009
  • アブシジン酸不活性化による休眠解除
    文一総合出版 2009
  • Enzymatic synthesis of cyclic triterpenes
    Nova Publishers 2009
ｍore...
Lectures and oral presentations  (19)：
  • Functional analysis of plant double-length tyrosyl-tRNA synthetase from <I>Arabidopsis thaliana</I>.
    (27th tRNA conference 2018)
  • Arabidopsis histidyl-tRNA synthetase with an appended domain bestowed anthocyanin and lignin production upon overexpression in plants.
    (IUBMB Focused Meeting on the Aminoacyl-tRNA Synthetases. 2017)
  • 植物由来アミノアシルtRNA合成酵素の二次機能の探索
    (第39回日本分子生物学会年会 2016)
  • シロイヌナズナ由来二量体型チロシルtRNA合成酵素の機能解析
    (第39回日本分子生物学会年会 2016)
  • Studies on plant and fungal tRNA synthetases in search for non-canonical functions.
    (26th tRNA Conference 2016)
ｍore...
Education (3)：
  • 1995 - 1998 The University of Tokyo Graduate School of Pharmaceutical Sciences
  • 1993 - 1995 Tokyo Institute of Technology Graduate School, Division of Natural Science
  • 1989 - 1993 Tokyo Institute of Technology Faculty of Science Department of Chemistry
Professional career (1)：
  • 博士(薬学) (東京大学)
Work history (6)：
  • 2020/04 - 現在 Meiji University School of Agriculture
  • 2010/04 - 2020/03 Meiji University School of Agriculture
  • 2005/04 - 2010/03 Assistant Professor
  • 2002/09 - 2005 Researcher
  • 2000/09 - 2002 Scripps Research Institute Research Associate
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Association Membership(s) (5)：
日本生薬学会 ,  植物化学調節学会 ,  日本植物生理学会 ,  日本農芸化学会 ,  日本分子生物学会
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