Niwa Takashi

ニワタカシ | Niwa Takashi

Affiliation and department：
Job title： Professor
Homepage URL (2)： https://niwagroup.jp , https://niwagroup.jp/home-en/

Research field (4)： Radiology , Synthetic organic chemistry , Bioorganic chemistry , Structural/physical organic chemistry

Research keywords (11)： organic synthesis , asymmetric reaction , 遷移金属 , 触媒 , 有機反応化学 , Transition Metal , Catalysis , Organic Reaction , Labeling chemistry , PET Imaging , Radiochemistry

Research theme for competitive and other funds (19)：

2023 - 2028 天然物が織り成す化合物潜在空間が拓く生物活性分子デザイン
2023 - 2028 Efficient extension of chemical library by chemoselective modification of complex molecules
2023 - 2026 多機能化のための生体親和性クリックケミストリーの創成
2023 - 2024 大きな歪みを有する反応性化学種の外部刺激を用いた発生制御
2022 - 2024 カチオン性有機金属化学の開拓

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Papers (51)：

丹羽節, 田原強, Chase Charles E., Fang Francis G., 中岡貴義, 入江さつき, 林中恵美, 和田康弘, 向井英史, 増富健吉, et al. 脳膠芽腫のコンパニオン診断用PETトレーサーとしての[11C]エリブリンの合成. JSMI Report. 2024. 17. 1. 30-33
Kenji Watanabe, Qiyue Mao, Zhouen Zhang, Machi Hata, Masahito Kodera, Hiroaki Kitagishi, Takashi Niwa, Takamitsu Hosoya. Clickable bisreactive small gold nanoclusters for preparing multifunctionalized nanomaterials: application to photouncaging of an anticancer molecule. Chemical science. 2024. 15. 4. 1402-1408
Takashi Niwa, Tadashi Takimoto, Yuki Sakata, Takamitsu Hosoya. Palladium-Catalyzed ipso-Borylation of Aryl Halides Promoted by Lewis Acid-Mediated Electrophilic Activation of Aryl(halo)palladium(II) Complex. Organic Letters. 2023
Jumpei Taguchi, Takumi Okuyama, Satomi Tomita, Takashi Niwa, Takamitsu Hosoya. Synthesis of Multisubstituted Aromatics via 3-Triazenylarynes. Organic Letters. 2023. 25. 38. 7030-7034
Manon Dubol, Jana Immenschuh, My Jonasson, Kayo Takahashi, Takashi Niwa, Takamitsu Hosoya, Sara Roslin, Johan Wikström, Gunnar Antoni, Yasuyoshi Watanabe, et al. Acute nicotine exposure blocks aromatase in the limbic brain of healthy women: A [11C]cetrozole PET study. Comprehensive psychiatry. 2023. 123. 152381-152381

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MISC (53)：

渡邊賢司, 寺尾和花, 喜井勲, 中川れい子, 丹羽節, 細谷孝充, 細谷孝充. 赤色光によるアンケージングが可能な3-アシルインドリジンの簡便合成. 反応と合成の進歩シンポジウム講演要旨集. 2020
Zhouen Zhang, Takashi Niwa, Yasuyoshi Watanabe, Takamitsu Hosoya. Facile radiosyntheses of [C-11]tetrazoles and [C-11]triazines from (hetero)arylborons. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2019. 62. S243-S244
Zhouen Zhang, Takashi Niwa, Yasuyoshi Watanabe, Takamitsu Hosoya. Palladium/copper-mediated rapid C-11-cyanation of (hetero)arylstannanes. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2019. 62. S48-S49
丹羽節, 細谷孝充. 分子をつくり変える -PETイメージングへの応用に向けて-. 現代化学. 2018. 568. 7. 42-46
植竹裕太, 丹羽節, 阪口博信, 大橋理人, 生越專介, 細谷孝充. 銅触媒を用いた2,2-ジフルオロビニルアレーン類のトランス位選択的脱フッ素ホウ素化反応の開発. 有機合成シンポジウム講演要旨集. 2017. 112th. 78-79

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Books (1)：

ファインケミカルシリーズ有機フッ素化合物の最新動向
シーエムシー出版 2018

Lectures and oral presentations (59)：

標識前駆体合成のイノベーション
(第58回日本核医学会学術総会シンポジウム診断と治療の基盤となる核薬学研究の最先端 2018)
Development of a synthetic building block for fluoroalkenes by Cu-catalyzed defluoroborylation
(2018)
ボリル(フルオロ)アルケンを用いたモノフルオロアルケン類の合成法の開発
(第41回フッ素化学討論会 2018)
身体の中の分子を見る-がんなどの早期発見を可能にするPET
(平成30年度大阪府高圧ガス保安大会講演会 2018)
脱フッ素ホウ素化反応を活用したアミド医薬品のフルオロアルケンミミック化合物の合成とその評価
(Pineering Project: Chemical Probe 第一回合同合宿セミナー 2018)

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Education (4)：

2006 - 2009 Kyoto University Graduate School of Engineering Department of Material Chemistry
2004 - 2006 The University of Tokyo School of Science Department of Chemistry
2002 - 2004 The University of Tokyo Faculty of Science Department of Chemistry
2000 - 2002 The University of Tokyo Collage of Arts and Sciences

Professional career (1)：

Ph. D (Engineering) (Kyoto University)

Work history (7)：

2023/04 - 現在 Kyushu University Graduate School of Pharmaceutical Sciences Professor
2021/10 - 2023/03 Tokyo Medical and Dental University Institute of Biomaterials and Bioengineering Associate Professor
2018/04 - 2021/09 RIKEN Center for Biosystems Dynamics Research Deputy Team Leader
2016/04 - 2018/03 RIKEN Center for Life Science Technologies Deputy Team Leader
2013/04 - 2016/03 RIKEN CLST Research Scientist

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Committee career (2)：

2023/01 - 現在 Thieme Chemistry Synthesis Advisory Board
2017/04 - 現在日本分子イメージング学会事務局員

Awards (14)：

2023/03 - The Chemical Society of Japan The BCSJ Award Synthesis of 11C-Radiolabeled Eribulin as a Companion Diagnostics PET Tracer for Brain Glioblastoma
2022/05 - Japanese Society for Molecular Imaging Best Presentation Award in the 16th Annual Meeting of Japanese Society for Molecular Imaging Synthesis of 11C-Radiolabeled Eribulin via Henry Reaction
2020/01 - Thieme Thieme Chemistry Journals Award
2019/04 - MEXT The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology, The Young Scientists' Prize
2018/06 - RIKEN RIKEN BAIHO Award

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Association Membership(s) (8)：

Japanese Society of Nuclear Medicine , 日本フッ素化学会 , THE PHARMACEUTICAL SOCIETY OF JAPAN , Japanese Society of Molecular Imaging , JAPANESE SOCIETY FOR CHEMICAL BIOLOGY , 日本化学会 , 有機合成化学協会 , 近畿化学協会

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