Rchr
J-GLOBAL ID:201001069870112040   Update date: Apr. 17, 2024

Watanabe Naoki

ワタナベ ナオキ | Watanabe Naoki
Affiliation and department:
Job title: Professor
Other affiliations (1):
Homepage URL  (2): http://www.pharm2.med.kyoto-u.ac.jp/http://www.med.kyoto-u.ac.jp/en/organization-staff/research/doctoral_course/r-020/
Research field  (1): Cell biology
Research keywords  (14): Brownian ratchet force sensor ,  kinase inhibitor ,  Single-molecule imaging ,  Pharmacology ,  Cell Biology ,  Super-resolution microscopy ,  分子標的薬 ,  メカノセンス ,  フォルミンファミリー ,  細胞分子イメージング ,  target-based drug ,  mechanotransduction ,  formin homology proteins ,  live-cell single-molecule imaging
Research theme for competitive and other funds  (17):
  • 2022 - 2025 分子・構造変換のリアルタイム可視化からの病気の解明と治療戦略
  • 2019 - 2022 Elucidation of mechanotransduction mechanisms with visualization of molecules
  • 2015 - 2021 多重高密度超解像顕微鏡IRISによる多分子複合体マッピング
  • 2011 - 2014 アクチン重合装置の蛍光単分子イメージングによる機械受容細胞シグナルの可視化解明
  • 2009 - 2010 アクチン単量体-線維のホメオスターシスを司る細胞シグナルによる物理ストレス応答
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Papers (81):
  • Sawako Yamashiro, David M. Rutkowski, Kelli Ann Lynch, Ying Liu, Dimitrios Vavylonis, Naoki Watanabe. Force transmission by retrograde actin flow-induced dynamic molecular stretching of Talin. Nature Communications. 2023. 14. 1
  • Qianli Zhang, Akitoshi Miyamoto, Naoki Watanabe. Protocol to generate fast-dissociating recombinant antibody fragments for multiplexed super-resolution microscopy. STAR Protocols. 2023. 4. 3. 102523-102523
  • Akitoshi Miyamoto, Naoki Watanabe. Possible application of IRIS multiplexed super-resolution microscopy for pathological analysis. Precision Medicine. 2023. 6. 8. 33-37
  • Naoki Watanabe. Brownian Ratchet-based Force Sensor, Lamellipodium. Seibutsu Butsuri. 2023. 63. 3. 143-147
  • Naoki Watanabe. Brownian ratchet force sensor at the contacting point between F-actin barbed end and lamellipodium tip plasma membrane. Plasma Membrane Shaping. 2023. 295-306
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MISC (67):
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Books (7):
  • 阻害剤・活性化剤ハンドブック
    羊土社 2019
  • ラング・デール薬理学
    エルゼビア・ジャパン, 丸善出版 (発売) 2018 ISBN:9784621301708
  • 京大発!フロンティア生命科学
    2018
  • Experimental Medicine
    Yodosha 2014
  • A possible role of homeostasis between monomeric and filamentous actin in filament nucleation revealed by pharmacokinetic modeling.
    Springer 2009
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Education (4):
  • - 1997 Kyoto University
  • - 1997 Kyoto University Graduate School, Division of Medicine
  • - 1990 Kyoto University Faculty of Medicine
  • - 1990 Kyoto University Faculty of Medicine
Professional career (1):
  • PhD (Kyoto University)
Work history (8):
  • 2015/01 - 現在 Kyoto University Graduate School of Biostudies Laboratory of Single-Molecule Cell Biology Professor
  • 2014/07 - 現在 Kyoto University Faculty of Medicine Pharmacology Professor
  • 2010/04 - 2014/06 Tohoku University Graduate School of Life Sciences, Department of Biomolecular Sciences, Division of Molecular Biosystems,Laboratory of Single-Molecule Cell Biology Professor
  • 2002/06 - 2010/03 Kyoto University Faculty of Medicine Pharmacology Associate Professor
  • 1999 - 2002 Harvard University
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Awards (2):
  • 2005 - 日本学術振興会賞(第1回、平成16年度)
  • 2005 - JSPS Prize (FY2004)
Association Membership(s) (5):
日本生物物理学会 ,  日本分子生物学会 ,  日本薬理学会 ,  日本生化学会 ,  日本細胞生物学会
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