Rchr
J-GLOBAL ID:201001087018875630
Update date: Nov. 14, 2024
Kobayashi Shogo
Kobayashi Shogo
Affiliation and department:
Job title:
准教授
Research field (1):
General surgery, pediatric surgery
Research keywords (2):
Surgery and clinical oncology
, 病態制御外科
Research theme for competitive and other funds (35):
- 2022 - 2025 肝癌微小環境における腫瘍関連マクロファージを中心とした細胞間相互作用の解明
- 2022 - 2025 Overcoming treatment resistance by removal senescent cancer cells targeting glutamine metabolism in pancreatic ductal adenocarcinoma
- 2022 - 2025 末梢血・門脈血中microRNA解析による臓器別転移機序の解明と個別化治療の開発
- 2022 - 2025 AI liquid biopsyが駆動する膵癌微小環境多様性解析と治療抵抗性打破
- 2022 - 2025 肝胆膵領域癌の浸潤過程における、周囲環境細胞との相互干渉の解析と制御
- 2022 - 2025 1型糖尿病に対する脂肪由来幹細胞を用いた新規膵島移植療法の開発
- 2021 - 2024 3次元血管化膵組織による1型糖尿病に対する新規膵島移植治療の開発
- 2021 - 2024 Establishment of personalized medicine for the dramatic improvement in the prognosis of pancreatic cancer patients
- 2019 - 2022 移植・再生医療に向けた肝・膵組織の三次元立体構築
- 2019 - 2022 Rubicon can predict prognosis in patients of pancreatic ductal adenocarcinoma after neoadjuvant chemoradiotherapy
- 2018 - 2021 Analyses of tumor progression and/or invasion of biliary tract cancers and implication of multimodal treatment.
- 2017 - 2019 Establishment of Highly Intrahepatic Metastatic Cell Line of HCC by In Vivo Selection and Investigation of Mechanism by Integrated Microarray Analysis
- 2015 - 2018 Analyses regarding heterogeneity of resistance for chemo- or chemo-radiation therapy in biliary tract cancer
- 2015 - 2018 The significance of c-myc expression in pancreatic cancer
- 2014 - 2017 Function analysis of exosome derived from hepatocellular carcinoma cells under hypoxia for tumor angiogenesis, invasion and metastasis
- 2014 - 2016 Development of a therapeutic option for anti-cancer drug-resistant malignancies via reprograming method using microRNAs.
- 2013 - 2016 Comprehensive characterization of next generation strategy to improve clinical islet transplantation
- 2013 - 2016 Investigation of microRNA interaction between pancreatic cancer cells and the stromal cells aiming to overcome the resistance to chemotherapeutic drugs.
- 2013 - 2015 肝移植における抗ドナー特異抗体産生意義の解明と個別化免疫療法の探求
- 2012 - 2015 Evaluation of the mechanism of liver regeneration focused on intracellular signal transduction and Non-coding RNA expression
- 2012 - 2015 Change of cancer and pericancerous tissue induced by inflammation, IL-6/TGF-beta crosstalk, in biliary tract cancers.
- 2012 - 2014 Therapeutic applications and effects on liver cancer cells by reprogramming related miRNA
- 2010 - 2012 Involvement of microRNA in the sensitivity prediction ofpreoperative chemoradiotherapy in pancreatic cancer
- 2010 - 2011 Inflammation inducing resistance for anti-cancer drug
- 2009 - 2011 The expandion in application of novel treatment through the liver specific siginaling pathway for the intractable and advanced hepatocellular carcinoma
- 2009 - 2011 Establishment of non-invasive diagnostic methods for allograft dysfunction and real-time monitoring of immunological status in liver transplant
- 2009 - 2010 肝癌症例末梢血中の転移形成能力を有する癌細胞の検出
- 2008 - 2010 肝胆膵領域の新規バイオマーカーの探索
- 2007 - 2008 Development of potential new treatment for theHCC targeting specificsignal and molecules
- 2007 - 2008 Diagnostic system for acute cellular rejection in livertransplantation using protemomic analysis of bile
- 2007 - 2008 Apoptosis related chemoresistance in hepato-biliary-pancreaticcancer
- 放射光を用いた肝微細構造解析
- Microangiogram in the liver using synchrotron radiation
- Genes transfection in transplant.
- 移植に対する遺伝子導入
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Papers (706):
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Hiroki Ueda, Hidenori Takahashi, Shogo Kobayashi, Yoshito Tomimaru, Masahiko Kubo, Kazuki Sasaki, Yoshifumi Iwagami, Daisaku Yamada, Tadafumi Asaoka, Takehiro Noda, et al. ASO Author Reflections: Potential of Peripheral Plasma Exosomal miRNA: miR-6855-5p Could Predict Radiosensitivity in Patients with Pancreatic Cancer, and Enhances Radioresistance. Annals of surgical oncology. 2024
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Hiroki Ueda, Hidenori Takahashi, Shogo Kobayashi, Masahiko Kubo, Kazuki Sasaki, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Tadafumi Asaoka, Takehiro Noda, et al. miR-6855-5p Enhances Radioresistance and Promotes Migration of Pancreatic Cancer by Inducing Epithelial-Mesenchymal Transition via Suppressing FOXA1: Potential of Plasma Exosomal miR-6855-5p as an Indicator of Radiosensitivity in Patients with Pancreatic Cancer. Annals of surgical oncology. 2024
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Hiroki Ueda, Hidenori Takahashi, Ryoto Sakaniwa, Tetsuhisa Kitamura, Shogo Kobayashi, Yoshito Tomimaru, Masahiko Kubo, Kazuki Sasaki, Yoshifumi Iwagami, Daisaku Yamada, et al. Preoperative treatment response prediction for pancreatic cancer by multiple microRNAs in plasma exosomes: Optimization using machine learning and network analysis. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2024
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Daisaku Yamada, Yu Takeda, Hidenori Takahashi, Kazuki Sasaki, Yoshifumi Iwagami, Yoshito Tomimaru, Takehiro Noda, Shogo Kobayashi, Tadafumi Asaoka, Junzo Shimizu, et al. Preoperative nutritional status is a useful predictor of the feasibility of postoperative treatment in octogenarian-plus pancreatic ductal adenocarcinoma patients. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 2024. 50. 12. 108650-108650
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Hiroki Ueda, Hidenori Takahashi, Hirofumi Akita, Yoshito Tomimaru, Shogo Kobayashi, Masahiko Kubo, Yousuke Mukai, Reishi Toshiyama, Kazuki Sasaki, Shinichiro Hasegawa, et al. Prognostic impact of aberrant right hepatic artery involvement in patients with pancreatic cancer: A multicenter retrospective cohort study. Journal of surgical oncology. 2024
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MISC (336):
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福田 泰也, 福井 秀行, 山田 大作, 小林 省吾, 額原 敦, 福田 周一, 大塚 正久, 橋本 和彦, 石川 原, 肥田 仁一, et al. MRIのプロトン密度脂肪率による脂肪膵の評価と膵癌のimaging predictorとしての有用性. 膵臓. 2023. 38. 3. A372-A372
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Masahiro Tanemura, Kenta Furukawa, Manabu Mikamori, Tadafumi Asaoka, Yasuo Urata, Kentaro Kishi, Daisaku Yamada, Shogo Kobayashi, Hidetoshi Eguchi. Development of modified telomerase-specific adenovirus-based identification for viable-peritoneal tumor cells in peritoneal lavage fluid in resectable pancreatic cancer. CANCER RESEARCH. 2022. 82. 12
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Masahiro Tanemura, Kenta Furukawa, Manabu Mikamori, Tadafumi Asaoka, Yasuo Urata, Kentaro Kishi, Daisaku Yamada, Shogo Kobayashi, Hidetoshi Eguchi. Development of modified telomerase-specific adenovirus-based identification for viable-peritoneal tumor cells in peritoneal lavage fluid in resectable pancreatic cancer. CANCER RESEARCH. 2022. 82. 12
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竹田佑, 竹田佑, 千々松良太, 小林省吾, 北風雅敏, 北風雅敏, 山田大作, 高橋秀典, 森正樹, 土岐祐一郎, et al. Integration and reconstruction of single-cell RNA sequencing datasets for pancreatic ductal adenocarcinoma. 日本癌学会学術総会抄録集(Web). 2022. 81st
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立川章太郎, 玉利慶介, 千々松良太, 光藤傑, 秋田裕史, 小林省吾, 村雲芳樹, 土岐祐一郎, 江口英利, 小川和彦, et al. m6A-regulated PLK1 cell cycle homeostasis as a potential target of radiotherapy in pancreatic adenocarcinoma. 日本癌学会学術総会抄録集(Web). 2022. 81st
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Lectures and oral presentations (6):
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胆道癌における治療抵抗因子の腫瘍局在と、術前化学(放射線)治療における発現の意義
(日本外科学会定期学術集会抄録集 2019)
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膵臓移植後合併症に対するIVRの有用性
(日本膵・膵島移植研究会プログラム・抄録集 2019)
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胆道癌術後の大量肝切除状態におけるGEMまたはS-1療法の第I/II相試験(KHBO1003/1208)
(日本癌治療学会学術集会抄録集 2018)
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胆道癌に対する集学的治療の現状 多施設研究によって胆道癌の臨床研究を賦活化する
(日本癌治療学会学術集会抄録集 2018)
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新規膵癌マーカーであるLRGの上皮間葉転換ならびに転移に関する意義
(膵臓 2018)
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Works (1):
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Detection of Magnetic Nanoparticles in Lymph Nodes of Rat by high Tc SQUID
2001 -
Education (5):
- - 2004 Osaka University Graduate School, Division of Medical Sciences
- - 2004 Osaka University
- - 1996 Osaka University Faculty of Medicine Medical School
- - 1996 Osaka University Faculty of Medicine
- - 1996 Osaka University Faculty of Medicine
Work history (11):
- 2017/04 - 現在 大阪大学消化器外科
- 2014/04 - 2017/03 大阪国際がんセンター(旧 大阪府立成人病センター)
- 2007/07 - 2014/03 大阪大学消化器外科
- 2006 - 2007 : 大阪大学大学院医学系研究科 特任助手
- 2007 - -: - 大阪大学大学院医学系研究科 助教
- 2007 - -: 大阪大学大学院医学系研究科 特任助教
- 2004 - 2006 : 日本学術振興会海外特別研究員
- 2003 - 2006 : メイヨークリニック 消化器肝臓病学 研究員
- 2000 - 2001 : マイアミ大学肝臓消化器移植科
- 1997 - 2000 : 大阪府立成人病センター 外科レジデント
- 1996 - 1997 : 大阪大学医学部附属病院 研修医
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Association Membership(s) (16):
日本癌学会
, 日本肝癌研究会
, 日本内視鏡外科学会
, 日本消化器病学会
, 日本臨床外科学会
, 日本消化器外科学会
, 日本肝移植研究会
, 日本肝胆膵外科学会
, 日本膵臓学会
, 日本消化器内視鏡学会
, 日本がん治療学会
, 日本膵・膵島移植研究会
, 日本胃癌学会
, 日本移植学会
, 日本胆道学会
, 日本外科学会
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