Nakashima Akio

ナカシマアキオ | Nakashima Akio

Affiliation and department：
Job title： Associate Professor

Research field (2)： Molecular biology , Functional biochemistry

Research keywords (5)： Functional Biochemistry , Molecular Biology , シグナル伝達 , 栄養シグナリング , Target of rapamycin (TOR)

Research theme for competitive and other funds (12)：

2022 - 2025 Establishment and spread of the new assay for sperm flagellar function to improve artificial insemination results in the cattle
2022 - 2025 減数分裂におけるTORC1キナーゼおよびオートファジーの機能制御の分子機構
2019 - 2021 Analyses of 3-dimensional rotation for the purpose of reconsidering criteria for the evaluation of flagellar functions in bull sperm
2016 - 2019 ウシ凍結前精子の耐凍能判定法の確立を目的としたSPACA1タンパク質の解析と利用
2014 - 2017 モデル生物を用いた減数分裂期におけるTORC1の活性化と生理機能の分子機構の解明

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Papers (36)：

Takuya Kano, Ryosuke Tsumagari, Akio Nakashima, Ushio Kikkawa, Shuji Ueda, Minoru Yamanoue, Nobuyuki Takei, Yasuhito Shirai. RalA, PLD and mTORC1 Are Required for Kinase-Independent Pathways in DGKβ-Induced Neurite Outgrowth. Biomolecules. 2021. 11. 12
Shinya Matsuda, Ushio Kikkawa, Akio Nakashima. The S. pombe CDK5 Orthologue Pef1 Cooperates with Three Cyclins, Clg1, Pas1 and Psl1, to Promote Pre-Meiotic DNA Replication. Biomolecules. 2021. 11. 1
Taiki Nagano, Tetsushi Iwasaki, Kengo Onishi, Yuto Awai, Anju Terachi, Shione Kuwaba, Shota Asano, Ryoko Katasho, Kiyoko Nagai, Akio Nakashima, et al. LY6D-induced macropinocytosis as a survival mechanism of senescent cells. The Journal of biological chemistry. 2020. 296. 100049-100049
Shinya Matsuda, Ushio Kikkawa, Haruka Uda, Akio Nakashima. The S. pombe CDK5 ortholog Pef1 regulates sexual differentiation through control of the TORC1 pathway and autophagy. Journal of cell science. 2020. 133. 17
Hiroko Nakai, Ryosuke Tsumagari, Kenta Maruo, Akio Nakashima, Ushio Kikkawa, Shuji Ueda, Minoru Yamanoue, Naoaki Saito, Nobuyuki Takei, Yasuhito Shirai. mTORC1 is involved in DGKβ-induced neurite outgrowth and spinogenesis. Neurochemistry international. 2020. 134. 104645-104645

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MISC (9)：

Yoko Otsubo, Akio Nakashima, Masayuki Yamamoto, Akira Yamashita. TORC1-dependent phosphorylation targets in fission yeast. Biomolecules. 2017. 7. 3. e50
Takuya Kano, Hiroko Nakai, Akio Nakashima, Ushio Kikkawa, Naoaki Saito, Nobuyuki Takei, Shuji Ueda, Minoru Yamanoue, Yasuhito Shirai. mTOR is involved in both kinase activity-dependent and -independent pathways of DGK beta-regulated neurite and branch induction. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 100P-100P
H. Nakai, N. Takei, A. Nakashima, U. Kikkawa, N. Saito, S. Ueda, M. Yamanoue, Y. Shirai. Involvement of mTOR in diacylglycerol kinase beta (DGK beta)-induced neurite blanching and spine formation. FEBS JOURNAL. 2012. 279. 383-384
原賢太, NAKASHIMA AKIO, 吉川潮. アミノ酸センシングシステムとしてのmTOR複合体1の機序. 実験医学. 2011. 29. 865-870
Akio Nakashima, Fuyuhiko Tamanoi. Conservation of the Tsc/Rheb/TORC1/S6K/S6 signaling in fission yeast. Enzymes. 2010. 28. C. 167-187

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Books (3)：

Lectures and oral presentations (38)：

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Education (1)：

Professional career (2)：

Association Membership(s) (2)：

酵母遺伝学フォーラム , 日本分子生物学会

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