Rchr
J-GLOBAL ID：201101002341846608
Update date: Aug. 19, 2024
Kanehiro Hayashi
ハヤシ カネヒロ | Kanehiro Hayashi
Affiliation and department：
Job title：
Assistant Professor/Senior Assistant Professor
Research field (2)：
Neuroscience - general
, Neuroanatomy and physiology
Research theme for competitive and other funds (4)：
- 2021 - 2026 Elucidation of pathological mechanisms of neuropsychiatric disorders by analyses of postmortem brains
- 2021 - 2024 流体構造生化学連成解析によるニューロンの移動モードと大脳皮質形成の力学の解明
- 2018 - 2022 発生期にリーリンにより誘導される神経細胞凝集は大脳新皮質層構造の起点となるか?
- 2015 - 2018 大脳新皮質層構造形成の礎となる脳表層下における神経細胞集積機構
Papers (34)：
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Martina Riva, Sofia Ferreira, Kotaro Hayashi, Yoann Saillour, Vera P. Medvedeva, Takao Honda, Kanehiro Hayashi, Claire Altersitz, Shahad Albadri, Marion Rosello, et al. De novo monoallelic Reelin missense variants cause dominant neuronal migration disorders via a dominant-negative mechanism. Journal of Clinical Investigation. 2024. 134. 16
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Julio Leon, Satoshi Yoshinaga, Mizuki Hino, Atsuko Nagaoka, Yoshinari Ando, Jonathan Moody, Miki Kojima, Ayako Kitazawa, Kanehiro Hayashi, Kazunori Nakajima, et al. Integrative Transcriptomics Reveals Layer 1 Astrocytes Altered in Schizophrenia. 2024
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Kanadome T, Hayashi K, Seto Y, Eiraku M, Nakajima K, Nagai T, Matsuda T. Development of intensiometric indicators for visualizing N-cadherin interaction across cells. Communications Biology. 2022. 5. 1. 1065
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Hidenori Tabata, Megumi Sasaki, Masakazu Agetsuma, Hitomi Sano, Yuki Hirota, Michio Miyajima, Kanehiro Hayashi, Takao Honda, Masashi Nishikawa, Yutaka Inaguma, et al. Erratic and Blood Vessel-Guided Migration of Astrocyte Progenitors in the Cerebral Cortex.(Featured in “Editors’ Highlights” as one of the most exciting articles.). Nat. Commun. 2022. 13. 6571
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Teiichi Furuichi, Yuko Muto, Tetsushi Sadakata, Yumi Sato, Kanehiro Hayashi, Yoko Shiraishi-Yamaguchi, Yo Shinoda. The physiological role of Homer2a and its novel short isoform, Homer2e, in NMDA receptor-mediated apoptosis in cerebellar granule cells. Molecular Brain. 2021. 14. 1
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MISC (6)：
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Kanehiro Hayashi, Ayako Kitazawa, Ken-ichiro Kubo, Yuki Matsunaga, Kazuhiro Ishii, Kazunori Nakajima. Climbing mode of migration: A novel migration mode of pyramidal neurons in the developing hippocampus. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE. 2015. 47. 49-49
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Kanehiro Hayashi, Ken-ichiro Kubo, Ayako Kitazawa, Kazunori Nakajima. Cellular dynamics of neuronal migration in the hippocampus. FRONTIERS IN NEUROSCIENCE. 2015. 9
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定方 哲史, 篠田 陽, 林 周宏, 古市 貞一. 【脳神経系の情報伝達と疾患 さまざまなシグナル伝達因子の異常が引き起こす精神疾患・発達障害・神経変性疾患のメカニズム】発達障害 有芯小胞の分泌制御因子CAPS2と自閉症感受性. 実験医学. 2010. 28. 5. 699-705
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Tetsushi Sadakata, Yo Shinoda, Kanehiro Hayashi, Teiichi Furuichi. CAPS2-mediated dense-core vesicle secretion and autism susceptibility. Experimental Medicine. 2010. 28. 5. 63-69
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Yo Shinoda, Tetsushi Sadakata, Kanehiro Hayashi, Teiichi Furuichi. Animal models of autism. Brain science and mental disorders. 2009. 20. 4. 303-310
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Books (3)：
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‘Reelin’ in Encyclopedia of Signaling Molecules (2nd Edition)
Springer International Publishing 2018 ISBN:9783319671994
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有芯小胞の分泌制御遺伝子CAPS2と自閉症感受性
実験医学増刊(羊土社) 2010
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自閉症の感受性候補遺伝子と動物モデル.
脳と精神の医学 2009
Lectures and oral presentations (12)：
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A novel ALS/FTD model mouse expressing cytoplasmic mutant FUS leads neurodegeneration via synaptic disruption
(Neuroscience 2017 meeting 2017)
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Analysis of cortical development in a newly established mouse model of extremely preterm infants with brain injuries
(Neuroscience 2017 meeting 2017)
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Molecular mechanisms of Reelin-induced neuronal aggregation in the developing mouse neocortex
(18th International Congress of Developmental Biology 2017)
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Novel ALS/FTD model mice expressed cytoplasmic FUS in a toxic gain-of-function manner
(The 13th International Conference on Alzheimer’s and Parkinson’s Diseases 2017)
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Investigation of the molecular mechanisms underlying Reelin-induced neuronal aggregation in the mouse neocortex
(2016 The American Society for Cell Biology (ASCB) Annual Meeting, 2016)
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Education (5)：
- 1998 - 2003 東京大学 医学系研究科 脳神経医学
- 1998 - 2003 東京大学 医学系研究科 脳神経医学
- 1996 - 1998 Tokyo Institute of Technology 生命理工学研究科 バイオサイエンス専攻
- 1996 - 1998 Tokyo Institute of Technology 生命理工学研究科 バイオサイエンス専攻
- 1992 - 1996 Tokyo Institute of Technology 生命理工学部 生命理学科
Professional career (1)：
Association Membership(s) (4)：
日本解剖学会
, 日本生化学会
, 日本神経化学会
, 日本神経科学学会
