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J-GLOBAL ID:201101003850766130   Update date: Jan. 16, 2020

Yoshida Masahito

ヨシダ マサヒト | Yoshida Masahito
Affiliation and department:
Job title: Associate Professor
Homepage URL  (2): http://www.chem.tsukuba.ac.jp/kigoshi/j/top_j.htmlhttp://www.chem.tsukuba.ac.jp/kigoshi/j/top_j.html
Research field  (5): Biomolecular chemistry ,  Drug development chemistry ,  Chemical pharmacy ,  Bio-related chemistry ,  Synthetic chemistry
Research keywords  (3): Bioorganic Chemistry ,  Total Synthesis ,  Natural Products
Papers (45):
  • Ito, Shinya;Saito, Masazumi;Yoshida, Masahito;Takeuchi, Koh;Doi, Takayuki;Nagata, Kazuhiro. A BRET-based assay reveals collagen-Hsp47 interaction dynamics in the endoplasmic reticulum and small-molecule inhibition of this interaction. The Journal of Biological Chemistry. 2019
  • Ohsawa, Kosuke;Sugai, Masato;Zhang, Linnan;Masuda, Yuichi;Yoshida, Masahito;Doi, Takayuki. Total Synthesis and Structural Revision of Cyclotetrapeptide Asperterrestide A. The Journal of Organic Chemistry. 2019. 84. 11. 6765-6779
  • Yoshida,Masahito. Combinatorial Synthesis and Biological Evaluation of Destruxins. Chemical and Pharmaceutical Bulletin. 2019. 67. 10. 1023-1029
  • Ohyoshi, Takayuki;Mitsugi, Keisuke;Higuma, Tatsuya;Ichimura, Fumitaka;Yoshida, Masahito;Kigoshi, Hideo. Concise total syntheses of phelligridins A, C, and D. RSC Advances. 2019. 9. 7321-7323
  • Yoshida, Masahito;Adachi, Kenta;Murase, Hayato;Nakagawa, Hiroshi;Doi, Takayuki. Parallel Synthesis and Biological Evaluation of Destruxin E Analogs Modified with a Side Chain in the α-Hydroxycarboxylic Acid Moiety. European Journal of Organic Chemistry. 2019. 7. 1669-1676
more...
Patents (2):
  • 環状デプシペプチド化合物
  • 2ーヒドロキシベンズアルデヒド化合物、これを含有するコラーゲン細胞外分泌阻害剤および医薬品組成物
Lectures and oral presentations  (25):
  • Total Synthesis and Biological Evaluation of Biologically Active Natural Cyclopeptides Toward Elucidation of the Mode of Action
    (日本化学会 第99春季年会)
  • イノンに対する位置選択的環化反応による多様性指向型フラボノイド合成研究
    (第25回有機合成化学若手研究者の仙台セミナー 2010)
  • フラボノイド類の多様性指向型合成法の開発研究
    (第8回日本カテキン学会総会 2011)
  • フラボンおよびオーロン類の多様性指向型位置選択的合成法の開発
    (日本農芸化学会2013年度仙台大会 2013)
  • Destruxin E, a Potent Negative Regulator of OSteoclast Morphology: Solid-Phase library Synthesis and Biological Evaluation
    (DPhG Annual Meeting 2014 2014)
more...
Education (2):
  • 1997 - 2001 Tokyo Institute of Technology Department of Applied Chemistry, Faculty of Engineering
  • 2003 - 2006 Tokyo Institute of Technology Department of Applied Chemistry, Graduate School of Science and Technology
Professional career (3):
  • Bachelor of Engineering (Tokyo Institute of Technology)
  • Master of Engineering (Tokyo Institute of Technology)
  • Doctor of Engineering (Tokyo Institute of Technology)
Work history (5):
  • 2006/04 - 2006/04 ChemGenesis Inc. Postdoctoral fellow
  • 2006/05 - 2008/03 Max-Planck Institute of Molecular Physiology Postdoctoral fellow
  • 2008/04 - 2011/03 Graduate School of Pharmaceutical Sciences, Tohoku University COE fellow
  • 2011/04 - 2018/05 Graduate School of Pharmaceutical Sciences, Tohoku University Assistant Professor
  • 2018/06 - Faculty of Pure and Applied Sciences, University of Tsukuba Associate Professor
Association Membership(s) (4):
Chemical Society of Japan ,  THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE JAPANESE PEPTIDE SOCIETY
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