2019 - 2022 Atrial Fibrillation Suppression and Electrophysiological Mechanisms of Heavy Ion Beam in Pathological Rabbits
2018 - 2021 Novel therapeutic strategies for ventricular fibrillation as a mechanism of 3-dimensional scroll wave with filament.
2018 - 2021 Development of Strategic Control Technology Based on Phase Variance Analysis for Pathophysiology, Diagnosis, and Treatment of Intractable Arrhythmias
2017 - 2020 Rotors as Drivers of Torsades de Pointes and Ventricular Fibrillation
2015 - 2018 Novel ablative approaches based on computational science for atrial fibrillation driver
2015 - 2018 Evaluation by Frequency Analysis of Surface Electrocardiogram and Rotor Mapping in Left Atrum
2015 - 2018 Termination mechanisms of atrial fibrillation by rotor-based ablation and establishment of patient-tailored atrial fibrillation therapy
2015 - 2018 Arrhythmogenic gap junction remodeling in diseased hearts
2016 - 2018 Termination mechanisms of atrial fibrillation by rotor-based ablation and establishment of patient-tailored atrial fibrillation therapy(Fostering Joint International Research)
2014 - 2017 Role of CaMKII in an experimental model of ventricular fibrillation storm
2013 - 2015 Mechanisms of atrial regional infarction-related atrial fibrillation
2010 - 2015 Integrated investigation of cardiac excitation propagation dynamics and arrhythmogenic mechanisms
2007 - 2008 Mechanical stretch and fibrillation dynamics in the left atrium
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Papers (91):
Kota Kujime, Hiroshi Seno, Kenzaburo Nakajima, Masatoshi Yamazaki, Ichiro Sakuma, Kenichiro Yamagata, Kengo Kusano, Naoki Tomii. Explainable localization of premature ventricular contraction using deep learning-based semantic segmentation of 12-lead electrocardiogram. Journal of arrhythmia. 2024. 40. 4. 948-957
Keisuke Hori, Hiroshi Seno, Ichiro Sakuma, Masatoshi Yamazaki, Naoki Tomii. Phase Gradient Divergence for the Quantitative Detection of Focal Activation Events During Cardiac Fibrillation. Journal of Medical and Biological Engineering. 2023. 43. 4. 427-436
富井 直輝, 稲田 慎, 芦原 貴司, 山崎 正俊, 瀬野 宏, 佐久間 一郎, 中沢 一雄. Feasibility Study of Phase Variance Analysis on Three-dimensional Atrial Fibrillation Model(タイトル和訳中). 日本循環器学会学術集会抄録集. 2023. 87回. PJ101-6
Mari Amino, Masatoshi Yamazaki, Koichiro Yoshioka, Noboru Kawabe, Sachie Tanaka, Takashi Shimokawa, Ryoko Niwa, Naoki Tomii, Shigeto Kabuki, Etsuo Kunieda, et al. Heavy Ion Irradiation Reduces Vulnerability to Atrial Tachyarrhythmias - Gap Junction and Sympathetic Neural Remodeling. Circulation journal : official journal of the Japanese Circulation Society. 2022
Keigo Arai, Akihiro Kuwahata, Daisuke Nishitani, Ikuya Fujisaki, Ryoma Matsuki, Yuki Nishio, Zonghao Xin, Xinyu Cao, Yuji Hatano, Shinobu Onoda, et al. Millimetre-scale magnetocardiography of living rats with thoracotomy. Communications Physics. 2022. 5. 1
Sakuma I, Yamazaki M, Tomii N. Bioengineering Approaches in Arrhythmia Research at the University of Tokyo: https://www.youtube.com/watch?v=9yXxdRpzwJc. Heart Rhythm TV 2018, USA. 2018
Tomii N, Yamazaki M, Shibata N, Honjo H, Sakuma I. Statistical Guideline of Threshold Determination for Cardiac Spiral Wave Center Detection Using Phase Variance. IFMBE Proceedings 2018. 2018. 68. 299-302
Y. Kushiyama, H. Honjo, R. Niwa, H. Takanari, M. Yamazaki, Y. Takemoto, I. Sakuma, I. Kodama, K. Kamiya. Partial blockade of IK1 destabilizes the rotation center of spiral wave reentry without enhancement of wavefront-tail interactions in the arm. EUROPEAN HEART JOURNAL. 2012. 33. 820-820
2011/09 - Asia Pacific Heart Rhythm Society Young Investigator Award (1st prize) Role of the Left Atrial Anatomy in the Maintenance of Three-Dimensional Scroll Waves in Acute, Stretch-Related and Cholinergic Atrial Fibrillation
2010/05 - Heart Rhythm Society, USA Heart Rhythm Journal Award 2010 Mechanisms of stretch-induced atrial fibrillation in the presence and the absence of adrenocholinergic stimulation: interplay between rotors and focal discharges.
2007/10 - The Japanese Society of Electrocardiology Young Investigator Award (1st prize) Destabilization and Early Termination of Spiral-wave Reentry by a Class III Antiarrhythmic Agent, Nifekalant, in a Perfused 2-Dimensional Layer of Rabbit Ventricular Myocardium
2007/07 - Heart Rhythm Society, USA Heart Rhythm Society Fellowship Award Mechanisms of stretch-induced atrial fibrillation in the presence and the absence of adrenocholinergic stimulation: interplay between rotors and focal discharges.
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Association Membership(s) (6):
American Heart Association
, Heart Rhythm Society
, JAPANESE HEART RHYTHM SOCIETY
, 日本心電学会
, JAPANESE CIRCULATION SOCIETY
, THE JANPANESE SOCIETY OF INTERNAL MEDICINE