Rchr
J-GLOBAL ID:201101016048156428   Update date: Oct. 30, 2024

Lee Sachiko

Lee Sachiko
Research field  (1): Rehabilitation science
Research keywords  (4): motor recovery ,  rehabilitation ,  plasticity ,  spasticity
Research theme for competitive and other funds  (5):
  • 2021 - 2024 痙縮の軽減を目的としたIa線維受容器の抑制とその効果に関する研究
  • 2018 - 2020 脳梗塞後の痙縮出現と脳幹網様体での恒常的シナプス可塑性変化の関係についての研究
  • 2015 - 2016 脳梗塞後に生じる痙縮が麻痺筋の神経筋接合部に及ぼす影響
  • 2013 - 2015 spasticity発症マウスの運動神経細胞過興奮の機序とリハビリテーション効果
  • 2011 - 2013 Investigation of the mechanism for spasticity after cortical injury
Papers (16):
  • Shogo Isumi, Daiki Futamura, Takuto Hanasaki, Yukito Sako, Shotaro Miyata, Hirohito Kan, Yumika Suzuki, Naoki Hasegawa, Hajime Mushiake, Satoshi Kametaka, et al. Association of medullary reticular formation ventral part with spasticity in mice suffering from photothrombotic stroke. NeuroImage. 2024. 298. 120791-120791
  • Keisuke Inoue, Meiko Asaka, Sachiko Lee, Kinya Ishikawa, Dai Yanagihara. Gait disorders induced by photothrombotic cerebellar stroke in mice. Scientific reports. 2023. 13. 1. 15805-15805
  • Satoshi Kametaka, Mari Isobe, Kenshin Komata, Makoto Morinaga, Kazuma Nagahata, Sachiko Lee-Hotta, Yasushi Uchiyama, Masahiro Shibata, Hideshi Sugiura. Protective effects of hachimijiogan (HJG), a Japanese Kampo medicine, on cancer cachectic muscle wasting in mice. Biomedical research (Tokyo, Japan). 2023. 44. 5. 199-207
  • Makoto Morinaga, Naoki Sako, Mari Isobe, Sachiko Lee-Hotta, Hideshi Sugiura, Satoshi Kametaka. Aerobic Exercise Ameliorates Cancer Cachexia-Induced Muscle Wasting through Adiponectin Signaling. International journal of molecular sciences. 2021. 22. 6
  • Mitsuhiro Fujiwara, Natsumi Yoshito, Masahiro Iwata, Sachiko Lee-Hotta, Takayuki Inoue, Yosuke Aizawa, Satoshi Kametaka, Yuji Asai, Shigeyuki Suzuki. Median nerve injury does not contribute to early onset of decreased grip strength due to repetitive reaching and grasping tasks in rats. Neuro endocrinology letters. 2020. 41. 2. 76-85
more...
MISC (3):
  • 跡見順子, 李佐知子, 清水美穂, 藤田恵理, 跡見友章, 廣瀬昇, 田中和哉. 運動適応の細胞力学応答基盤(3):走運動は膝軟部組織細胞の細胞外基質適応を促進する. 日本運動生理学会大会プログラム・抄録集. 2013. 21st
  • Sachiko Lee, Masaki Ueno, Toshihide Yamashita. Downregulation of GABA signaling enhances axonal rewiring and contributes to spontaneous recovery of motor functions after traumatic brain injury. NEUROSCIENCE RESEARCH. 2010. 68. E426-E426
  • Sachiko Lee, Toshihide Yamashita. Downregulation of GABA(A)R alpha 1 subunit expression in the cortical neurons is associated with improvement of motor function after cortical contusion in mice. NEUROSCIENCE RESEARCH. 2009. 65. S216-S216
Books (1):
  • 人体の解剖生理学
    金芳堂 2017 ISBN:9784765317092
Lectures and oral presentations  (42):
  • Effect of continuous inhibition of Ia fiber’s activity on spasticity and spinal neural network after spinal cord injury
    (Federation of European Neuroscience Societies (FENS) Forum 2024)
  • Quantitative analysis of neural activity in the ventral nucleus of the medullary reticular nucleus in mice developing spasticity after stroke using activity-dependent manganese contrast-enhanced MRI.
    (Federation of European Neuroscience Societies (FENS) Forum 2024)
  • 活動依存性マンガン造影MRIを用いた脳梗塞痙縮発症マウスにおける延髄網様体腹側核の神経活動累積の定量解析
    (2023年度文部科学省学術変革領域研究学術研究支援基盤形成先端モデル動物支援プラットフォーム成果発表会 2024)
  • 脳梗塞後の神経可塑的変化における“REST”の発現変化の確認
    (第28回日本基礎理学療法学会学術大会 2023)
  • 脊髄損傷後早期におけるIa線維の持続的活動抑制による神経回路の可塑的変化と痙縮軽減効果の検討
    (第28回日本基礎理学療法学会学術大会 2023)
more...
Education (4):
  • 2005 - 2008 The University of Tokyo Graduate School, Division of General Culture Multi-Disciplinary Science
  • 2003 - 2005 Kobe University Graduate School, Division of Medical Sciences Department of Rehabilitation Science
  • 2001 - 2003 Kobe University Faculty of Medicine Faculty of Health Sciences
  • 1994 - 1997 College of Medical Technology, Kyoto University Faculty of Biomedical Technology
Professional career (2):
  • 保健学修士 (神戸大学)
  • Doctor of Philosophy (Multidisciplinary sciences) (The University of Tokyo)
Work history (3):
  • 2015/10 - 現在 名古屋大学大学院 医学系研究科総合保健学 予防・リハビリテーション療法学 准教授
  • 2010/10 - 2015/09 名古屋大学大学院 医学系研究科 総合保健学 予防・リハビリテーション療法学 助教
  • 2008/04/01 - 2010/09/30 Department of Molecular Neuroscience, Graduate School of Medicine, Osaka University Associate reseacher
Awards (1):
  • 2014/11 - 日本基礎理学療法学会 第1回日本基礎理学療法学会 学会長賞 脳梗塞後痙縮発症マウスの延髄網様体脊髄路切断によるHoffmann反射Rate dependent depressionの再現
Association Membership(s) (4):
日本リハビリテーション医学会 ,  Society For Neuroscience ,  The Japan Neuroscience Society ,  The Japanese Physical Therapy Association
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