J-GLOBAL ID:201101025633584280   Update date: Dec. 27, 2019

Hideyuki Mukai

Hideyuki Mukai
Affiliation and department:
Job title: Associate Professor
Homepage URL  (2): http://bioupdate.jphttp://bioupdate.jp
Research field  (7): 機能生物化学 ,  細胞生物学 ,  生物分子科学 ,  病態医化学 ,  構造生物化学 ,  神経内科学 ,  皮膚科学
Papers (81):
  • Mehruba M, Siddique SM, Mukai H. PKN1 controls the aggregation, spheroid formation, and viability of mouse embryonic fibroblasts in suspension culture. Biochemical and biophysical research communications. 2019
  • Siddique SM, Kubouchi K, Shinmichi Y, Sawada N, Sugiura R, Itoh Y, Uehara S, Nishimura K, Okamura S, Ohsaki H, Kamoshida S, Yamashita Y, Tamura S, Sonoki T, Matsuoka H, Itoh T, Mukai H. PKN1 kinase-negative knock-in mice develop splenomegaly and leukopenia at advanced age without obvious autoimmune-like phenotypes. Scientific reports. 2019. 9. 1. 13977
  • Uehara S, Udagawa N, Mukai H, Ishihara A, Maeda K, Yamashita T, Murakami K, Nishita M, Nakamura T, Kato S, Minami Y, Takahashi N, Kobayashi Y. Protein kinase N3 promotes bone resorption by osteoclasts in response to Wnt5a-Ror2 signaling. Science signaling. 2017. 10. 494
  • Mashud R, Nomachi A, Hayakawa A, Kubouchi K, Danno S, Hirata T, Matsuo K, Nakayama T, Satoh R, Sugiura R, Abe M, Sakimura K, Wakana S, Ohsaki H, Kamoshida S, Mukai H. Impaired lymphocyte trafficking in mice deficient in the kinase activity of PKN1. Scientific reports. 2017. 7. 1. 7663
  • Danno S, Kubouchi K, Mehruba M, Abe M, Natsume R, Sakimura K, Eguchi S, Oka M, Hirashima M, Yasuda H, Mukai H. PKN2 is essential for mouse embryonic development and proliferation of mouse fibroblasts. Genes to cells : devoted to molecular & cellular mechanisms. 2017. 22. 2. 220-236
Books (6):
  • MEFINFO 86
    Elsevier Science Publishers B.V. 1986
  • Encyclopedia of Molecular Medicine
    John Wiley & Sons, Inc. 2002
  • Protein kinase C Protocols
    Humana Press 2003
  • Methods in Enzymology:Regulators and Effectors of Small GTPases: Rho Family
    Elsevier 2006
  • Neuromethods:Protein kinase technologies
Lectures and oral presentations  (1):
  • PKN Interacting Proteins
    (International Conference on Molecular Biology Transcription/Replication Factors and Signal Transduction 1999)
Professional career (1):
  • M.D., Ph.D.
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