- 2018 - 2022 Elucidation and treatment development of the pathophysiology of glutamate-D-serine system in the white matter of schizophrenia
- 2012 - 2016 Investigation of development of new treatment for refractory depression by modification of glutamate neuropterans mission
- 2010 - 2016 Comprehensive Brain Science Network
- 2009 - 2011 Studies on the development of novel pharmacotherapy for schizophrenia that regulates the glutamate receptors
- 2004 - 2010 Research on Pathomechanisms of Brain Disorders
- 2005 - 2009 Elucidation of molecular pathomechanisms of schizophrenia
- 2007 - 2008 Studies on the development of glutamate system-targeted novel pharmacotherapy for schizophrenia
- 2005 - 2006 Development of nobel pharmacotherapy for schziphrenia targeted at the NMDA receptor-D-serine system
- 2003 - 2004 A study of molecular pathogenesis of anxiety disorders in the brain.
- 2002 - 2004 A neurodevelopmental pharmacological approach to the molecular pathophysiology of schizophrenic symptoms
- 2002 - 2003 精神分裂病関連遺伝子操作動物の作製とその行動および脳内分子の解析
- 2001 - 2002 The analysis of developmentally dependent, addictive drug-induced gene(s) in mental disorders
- 2001 - 2002 A molecular pathogenetic study of anxiety disorders in the brain.
- 2001 - 2002 Origin and regulation of endogenous D-serine in mammalian brain tissues
- 2000 - 2001 A pharmacological approach to the molecular basis of disturbed brain information processing of schizophrenia
- 1998 - 1999 精神分裂病における神経情報処理障害の原因となる遺伝子異常の探索
- 1997 - 1999 EXPLORATORY STUDY FOR ESTABLISHING A NEW THERAPY WITH ENDOGENOUS D-AMINO ACIDS IN MOTOR ATAXIA
- 1998 - 1998 情動・意欲の神経機構と病態のメカニズム
- 1996 - 1997 Molecular mechanisms of schizophrenic symptoms
- 1996 - 1997 Analysis of An Intracellular Ca^<2+>-release Factor, Cyclic ADP-ribose, in Brain
- 1995 - 1997 Metabolism and Physiological functions of endogenous D-serine
- 1994 - 1995 Molecular pharmacological approach to the disturbances of brain neuron circuits involved in schizophrenia
- 1992 - 1993 Schizophrenic sympyoms-related disturbance of cerebral neurotransmission
- 1991 - 1993 Study on pathoetilogy of schizophrenia and epilepsy fowsing on EAA newrons
- 1991 - 1992 Molecular Pharmacological Study on the Dysfunction of 5-HT-2 receptor-stimulated Transduction Signaling in Depression.
- 1990 - 1991 Behavioral and biochemical effects of schizophrenomimetic drugs, phencyclidine and methamphetamine, in the rat
- 1989 - 1990 Hyperresponsiveness of 5-HT-2 Receptor-Mediated Intracellular Camobilization in Platelets from the Depressed Patients and in C6 Glioma Cells Pretreated with Dexamethasone.
- 1989 - 1990 Clinical Study on Seasonal Affective Disorders From the View Point of Chronobiology
- 1988 - 1989 Attempt for development of a novel animal model for depression
- 1987 - 1988 Study on the function of monoamine receptors and transmembrane signal control in the affective disorders.
- 1987 - 1988 神経成長因子(NGF)合成促進薬物の抗痴呆薬としての応用・開発する研究
- 内在性ローセリンの脳における代謝および機能の解明と精神神経疾患の治療への応用
- 抗精神病薬抵抗性分裂病症状の分子メカニズムと新しい治療法に関する研究
- Studies on molecular mechanisms and movel therapies of neuroleptic-resistant symptoms of schizaphrenia
- Analysis of molecular mechamisms of metabolism and physiological functions of endogenous D-serine and its application to development of novel therapies for neuropsychiatr. c disorders
- Molecular mechanisms underlying psychostimslant-induced schizophrenia-like symptoms
- 神枢刺激薬による分裂済様症状の発現と再燃の分子機構の解明
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