Rchr
J-GLOBAL ID：201101034210531830
Update date: Nov. 18, 2025
Shinmyo Yohei
シンミョウ ヨウヘイ | Shinmyo Yohei
Affiliation and department：
Homepage URL (1)：
https://www.hama-med.ac.jp/education/fac-med/dept/neurophysiology/index.html
Research field (3)：
Neuroanatomy and physiology
, Developmental biology
, Neuroscience - general
Research keywords (8)：
大脳皮質
, 神経回路
, 軸索ガイダンス
, 脳回脳溝
, Draxin
, アストロサイト
, フェレット
, マウス
Research theme for competitive and other funds (21)：
- 2023 - 2026 大脳複雑化の分子メカニズムとその機能的意義の解明
- 2023 - 2025 複雑化した脳におけるアストロサイトのデコーディング
- 2021 - 2023 アストロサイト数の制御メカニズムの解明と脳回形成におけるその役割
- 2020 - 2023 軸索ガイダンスを切り口とした脳回形成機構の解明
- 2018 - 2021 Developmental mechanisms of the cerebral cortex in ferrets
- 2016 - 2019 Elucidation of developmental mechanisms of the cerebral cortex focusing on axon guidance
- 2016 - 2018 Regulation of small cell lung carcinoma cells by interference between axon guidance molecules and their receptors
- 2015 - 2018 Analysis of propagation molecule mechanism via exosome in Parkinson's disease related gene SNCA
- 2015 - 2017 Gene knockout in the cerebral cortex
- 2014 - 2016 糖鎖による軸索ガイダンス分子draxinの機能制御機構の解明
- 2011 - 2014 軸索ガイダンス分子ドラキシンの神経回路形成機能とそのシグナル機構解明
- 2011 - 2014 Draxin roles in thalamocortical projections.
- 2011 - 2013 多様な軸索投射パターンの形成機構の解明
- 2011 - 2011 軸索ガイダンス分子ドラキシンの神経回路形成機能とそのシグナル機構解明
- 2009 - 2010 Roles of Draxin signaling in formation of the corpus callosum and thalamocortical projections.
- 2008 - 2010 Comprehensive analyses of the axon guidance molecule Draxin
- 2008 - 2009 マウス大脳の神経回路形成におけるDraxinの役割
- 2007 - 2008 Identification and functional analysis of Receptor for Draxin, a repulsive guidance protein
- 2006 - 2007 Analysis of a novel repulsive axon guidance protein, Draxin
- 2006 - 2007 新規神経ガイダンス分子Draxin遺伝子欠損マウスの解析
- 2005 - 2006 網膜神経幹細胞におけるBMPアンタゴニストTsukushiの機能解析
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Papers (74)：
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Kengo Saito, Narufumi Kameya, Nguyen Chi Tai, Toshihide Hamabe-Horiike, Yohei Shinmyo, Hiroshi Kawasaki. Exploring the Mechanisms Underlying the Development and Evolution of the Mammalian Cerebrum Using Gyrencephalic Ferrets. Developmental neuroscience. 2025. 1-14
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Loc Dinh Nguyen, Ly Huong Nguyen, Dat Xuan Dao, Tsuyoshi Hattori, Mika Takarada-Iemata, Hiroshi Ishii, Takashi Tamatani, Hiroshi Kawasaki, Yohei Shinmyo, Kenta Onoue, et al. Impact of ATF6 deletion on the embryonic brain development. iScience. 2025. 28. 6. 112569-112569
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Tohru Yamagaki, Tomohiro Osugi, Yohei Shinmyo, Hiroshi Kawasaki, Honoo Satake. Quantitative Analysis of Neuropeptide Y (NPY) and C-Terminal Glycine-Extended NPY by Mass Spectrometry and Their Localization in the Developing and Sexual Adult Mouse Brains. ACS Chemical Neuroscience. 2025
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Yohei Shinmyo. Implications of draxin in neurological disorders. Frontiers in cell and developmental biology. 2025. 13. 1560940-1560940
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Narufumi Kameya, Itsuki Sakai, Kengo Saito, Toshihide Hamabe-Horiike, Yohei Shinmyo, Mitsutoshi Nakada, Satoru Okuda, Hiroshi Kawasaki. Evolutionary changes leading to efficient glymphatic circulation in the mammalian brain. Nature Communications. 2024. 15. 10048
ｍore...
MISC (5)：
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奥園 清香, 藤井 史彦, 松下 悠紀, 瀬戸山 大樹, 新明 洋平, 平良 遼志, 米元 耕輔, 赤峰 哲, 本村 良知, 實藤 雅文, et al. Shank3aは生後早期マウスのけいれん感受性を制御する. 日本小児科学会雑誌. 2023. 127. 2. 193-193
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Mishima Rei, Mishima Rei, Shinmyo Yohei, Kawasaki Hiroshi, Ogawa-Ochiai Keiko. Effect of maternal yokukansan treatment on somatosensory map formation in the cerebral cortex of newborn mouse pups. Traditional & Kampo Medicine. 2018. 5. 2. 98-105-105
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Roles of an axon guidance protein Draxin in neural circuit formation. 2016. 125. 2. 55-59
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M. Hossain, G. Ahmed, I. Naser, Y. Shinmyo, A. Ito, M. Riyadh, A. Felemban, X. Song, K. Ohta, H. Tanaka. The combinatorial guidance activities of draxin and Tsukushi are essential for forebrain commissure formation. JOURNAL OF NEUROCHEMISTRY. 2012. 123. 54-54
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Ayako Ito, Yohei Shinmyo, Naoko Kaneko, Yuki Hirota, Masahiro Yamaguchi, Kazunobu Sawamoto, Hideaki Tanaka, Kunimasa Ohta. Analysis of Tsukushi (TSK) function in the mouse brain. NEUROSCIENCE RESEARCH. 2010. 68. E245-E245
Work history (7)：
Association Membership(s) (5)：
日本発生生物学会
, 日本神経科学学会
, 日本神経化学会
, 日本分子生物学会
, 日本生理学会
