Rchr
J-GLOBAL ID:201101041717297630   Update date: Dec. 18, 2024

Harada Akihiro

Harada Akihiro
Affiliation and department:
Job title: professor
Homepage URL  (1): http://kaken.nii.ac.jp/ja/r/40251441
Research field  (3): Anatomy ,  Neuroanatomy and physiology ,  Cell biology
Research keywords  (33): 包括脳ネットワーク・データーベース委員会 ,  統合脳・病態脳・班友 ,  包括脳ネットワーク ,  蛋白質 ,  モ-タ-蛋白 ,  キネシン ,  神経細胞 ,  ジ-ンタ-ゲティング ,  上皮細胞 ,  遺伝子 ,  KIFC2 ,  神経原線維変化 ,  rab ,  loxP ,  マイクロアレー ,  LTP ,  TGN ,  標的遺伝子組換え ,  細胞・組織 ,  神経細胞死 ,  SNARE ,  Cre ,  トランスジェニックマウス ,  ノックアウトマウス ,  Cre recombinase ,  標的組換え法 ,  DiI ,  微小管 ,  シナプシン1 ,  細胞極性 ,  アルツハイマー病 ,  タウ ,  微小管関連蛋白
Research theme for competitive and other funds  (47):
  • 2021 - 2024 細胞の極性を制御する遺伝子の組織、個体での機能とその分子機構の解明
  • 2019 - 2023 細胞種を超えて保存される極性形成機構の解明
  • 2017 - 2022 上皮細胞の極性輸送における細胞小器官内選別輸送ゾーンの有無とその意義
  • 2017 - 2022 Toward an integrative understanding of functional zones in organelles
  • 2018 - 2021 Analyses of the in vivo roles of genes that regulate cell polarity and the elucidation of their molecular mechanism
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Papers (101):
  • Yu Zhang, Masataka Kunii, Manabu Taniguchi, Shin-Ichiro Yoshimura, Akihiro Harada. Rab6-Mediated Polarized Transport of Synaptic Vesicle Precursors Is Essential for the Establishment of Neuronal Polarity and Brain Formation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024. 44. 27
  • Akihiro Harada, Masataka Kunii, Kazuo Kurokawa, Takuya Sumi, Satoshi Kanda, Yu Zhang, Satomi Nadanaka, Koichiro M. Hirosawa, Kazuaki Tokunaga, Takuro Tojima, et al. Dynamic movement of the Golgi unit and its glycosylation enzyme zones. Nature Communications. 2024. 15. 1
  • Ji Wu, Kenta Moriwaki, Tatsuya Asuka, Ritsuko Nakai, Satoshi Kanda, Manabu Taniguchi, Tatsuki Sugiyama, Shin-Ichiro Yoshimura, Masataka Kunii, Takashi Nagasawa, et al. EHBP1L1, an apicobasal polarity regulator, is critical for nuclear polarization during enucleation of erythroblasts. Blood advances. 2023
  • Tomohiko Iwano, Tomoaki Sobajima, Sén Takeda, Akihiro Harada, Shin-ichiro Yoshimura. The Rab GTPase-binding protein EHBP1L1 and its interactors CD2AP/CIN85 negatively regulate the length of primary cilia via actin remodeling. Journal of Biological Chemistry. 2023. 102985-102985
  • Yuri Kondo, Atsushi Ozawa, Daisuke Kohno, Kazuma Saito, Battsetseg Buyandalai, Sayaka Yamada, Kazuhiko Horiguchi, Yasuyo Nakajima, Nobuyuki Shibusawa, Akihiro Harada, et al. The Hypothalamic Paraventricular Nucleus Is the Center of the Hypothalamic-Pituitary-Thyroid Axis for Regulating Thyroid Hormone Levels. Thyroid : official journal of the American Thyroid Association. 2022. 32. 1. 105-114
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MISC (50):
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Lectures and oral presentations  (6):
  • 選別輸送関連分子FAPP1及びFAPP2のノックアウトマウスの作製と解析について
    (日本解剖学会 2007)
  • Generation and analysis of mice deficient in FAPP1 or FAPP2, molecules involved in budding of vesicles targeted to apical domains from the trans-Golgi network
    (細胞生物学会 2007)
  • 「ノックアウトマウスの作成」
    (組織細胞化学講習会 2007)
  • Generation and analysis of mice deficient in FAPP1 or FAPP2, molecules involved in budding of vesicles targeted to apical domains from the trans-Golgi network
    (2007)
  • Generation of mice deficient in molecules involved in polarized transport
    (COE若手研究者国際セミナー 2006)
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Education (6):
  • - 1996 The University of Tokyo
  • - 1996 University of Tokyo Graduate School of Medicine Department of Anatomy and Cell Biology
  • The University of Tokyo Faculty of Medicine School of Medicine
  • The University of Tokyo Faculty of Medicine
  • The University of Tokyo Graduate School, Division of Medical Sciences
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Professional career (1):
  • 医学博士
Work history (6):
  • 2009/04 - Graduate School of Medicine, Osaka University Professor
  • 2001/07 - 2009/03 Gunma University Institute for Molecular and Cellular Regulation
  • 1997/04 - 2001/06 東京大学 大学院・医学系研究科 講師
  • 1996/07 - 1997/03 The University of Tokyo Faculty of Medicine
  • 1995/04 - 1996/07 The University of Tokyo Faculty of Medicine
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Committee career (2):
  • 日本解剖学会 評議員
  • 日本細胞生物学会 評議員
Association Membership(s) (6):
日本解剖学会 ,  日本神経科学会 ,  日本細胞生物学会 ,  日本分子生物学会 ,  The American Society for Cell Biology ,  アメリカ細胞生物学会
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