Rchr
J-GLOBAL ID:201101047494975800   Update date: May. 14, 2024

Sasaki Yukio

ササキ ユキオ | Sasaki Yukio
Affiliation and department:
Job title: 准教授
Homepage URL  (2): http://sasakilab.orghttp://en.sasakilab.org
Research field  (5): Pharmacology ,  Medical biochemistry ,  Cell biology ,  Molecular biology ,  Neuroscience - general
Research keywords  (35): Fragile X syndrome ,  Local translation ,  Synaptogenesis ,  セマフォリン ,  プレキシン ,  Fyn ,  チロシンリン酸化 ,  神経細胞死 ,  チロシンキナーゼ ,  Cdk5 ,  コラプシン ,  軸索ガイダンス ,  反発因子 ,  マイクロRNA ,  ラベンダスチンA ,  神経発生 ,  軸策輸送 ,  神経生物学 ,  翻訳調節 ,  神経回路網 ,  神経ガイダンス ,  横浜市 ,  軸索輸送 ,  4血管閉塞脳虚血 ,  チロシンホスファターゼ ,  神経細胞死因子ドーパ ,  細胞内情報伝達 ,  脳虚血上流因子内因性ドーパ ,  弧束核 ,  Nogo ,  PTPase ,  シナプス ,  成長円錐 ,  Synapse ,  Growth cone
Research theme for competitive and other funds  (10):
  • 2016 - 2019 Regulation of neural circuit by Fragile X Mental Retardation Protein - its relation to ubiquitination and local translation
  • 2013 - 2016 Role of local protein synthesis regulated by Fragile X Mental Retardation Protein during presynapse formation
  • 2012 - 2012 マイクロRNAの輸送マシナリーの解明と軸索機能における役割
  • 2010 - 2012 軸索ガイダンスにおける成長円錐の自律性と翻訳トランス因子の役割
  • 2001 - 2002 神経細胞死における成長円錐と細胞体のダイアログ
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Papers (62):
  • Ka Yin Chin, Shoichi Ishida, Yukio Sasaki, Kei Terayama. Predicting condensate formation of protein and RNA under various environmental conditions. BMC bioinformatics. 2024. 25. 1. 143-143
  • Renoma Takeda, Rie Ishii, Shumaia Parvin, Aki Shiozawa, Terukazu Nogi, Yukio Sasaki. Novel presynaptic assay system revealed that metformin ameliorates exaggerated synaptic release and Munc18-1 accumulation in presynapses of neurons from Fragile X syndrome mouse model. Neuroscience letters. 2023. 810. 137317-137317
  • Cristine R Casingal, Takako Kikkawa, Hitoshi Inada, Yukio Sasaki, Noriko Osumi. Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis. Molecular brain. 2020. 13. 1. 167-167
  • Yukio Sasaki. Local Translation in Growth Cones and Presynapses, Two Axonal Compartments for Local Neuronal Functions. Biomolecules. 2020. 10. 5
  • Masaru Takabatake, Yoshio Goshima, Yukio Sasaki. Semaphorin-3A Promotes Degradation of Fragile X Mental Retardation Protein in Growth Cones via the Ubiquitin-Proteasome Pathway. Frontiers in neural circuits. 2020. 14. 5-5
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MISC (27):
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Patents (1):
Books (1):
  • Cyclin Dependent Kinase 5 (Cdk5)
    Springer 2008 ISBN:0387788867
Professional career (1):
  • Ph.D. (Kobe University)
Work history (7):
  • 2013/04 - 現在 Yokohama City University Graduate School of Medical Life Scicence Functional Structure Laboratory, Division of Functional Structure Associate Professor
  • 2009/09 - 2013/04 Yokohama City University Graduate School of Medicine Department of Molecular Neuroscience and Neurobiology Contract Associate Professor
  • 2005/08 - 2009/08 Emory University School of Medicine Department of Cell Biology Instractor
  • 2002/09 - 2005/07 Albert Einstein College of Medicine Department of Neuroscience Research associate
  • 2001/01 - 2002/08 Yokohama City University School of Medicine Department of Pharmacology Lecturer
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