Rchr
J-GLOBAL ID:201101051015315903
Update date: Dec. 16, 2024
Iguchi Yoshio
Iguchi Yoshio
Affiliation and department:
Homepage URL (1):
https://www.researchgate.net/profile/Yoshio_Iguchi
Research field (2):
Neuroscience - general
, Experimental psychology
Research keywords (23):
Associative learning
, Instrumental learning
, Operant conditioning
, Motivation
, Habit
, Decision-making
, Drug-addicted
, Pavlovian conditioning
, Flavor aversion conditioning
, Stress
, Oxidative stress
, Resilience
, Basal ganglia
, Striatum
, Nucleus accumbens
, Dopamine
, Locus ceruleus
, Noradrenaline
, Chemogenetics
, Rodents
, Comparative psychology
, Animal psychology
, 包括脳ネットワーク
Research theme for competitive and other funds (13):
- 2024 - 2027 Elucidation of the dopaminergic system in the motivation management for goal-directed behavior
- 2023 - 2024 昆虫がにおいを感じる仕組みに学ぶほ乳類神経細胞の活性化戦略
- 2019 - 2022 Elucidating roles of ventral tegmental area dopaminergic neurons in motivation of appetitive goal-directed behavior
- 2016 - 2020 The neural basis of mode shift in decision making: the mechanism of its breakdown with the locus coeruleus as the starting point
- 2020 - Role of dopaminergic projections across the cerebral hemispheres in the motivational control of goal-directed behavior
- 2017 - 2019 Investigation of the link between individual difference in the decision style and vulnerability to psychiatric disorders
- 2014 - 2019 Technology for pathway-selective manipulation and control of neural circuit
- 2013 - 2016 Elucidating the functional significance of mild oxidative stress on adult rat brain: friend or foe?
- 2013 - 2015 Pre-stress performance in an operant learning predicts post-stress behavioral alterations in chronically stressed rats
- 2011 - 2012 The role of extrasynaptic GABAA receptor at the nucleus accumbens in major depressive disorder: a basic study using chronic unpredictable stress paradigm with rats
- 2011 - 2012 The role of the nucleus accumbens in deficit of decision making: a rodent study with the manipulations on dopamine tone
- 2007 - 2008 Animals, cognition and response to the contexts in which they havereceived either Pavlovian conditioning or instrumental training
- 2007 - 2007 Spatial forward- and backward-blocking in fish (goldfish and carps)
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Papers (21):
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Hata, Y, Matsui, H, Iguchi, Y, Samejima, K, Sawa, S. A reinforcement schedule with two types of temporal information. MethodsX. 2024. 13. 102831-102831
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Iguchi, Y, Benton, R, Kobayashi, K. A chemogenetic technology using insect Ionotropic Receptors to stimulate target cell populations in the mammalian brain. Neuroscience Research. 2024. (in press)
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Iguchi, Y, Fukabori, R, Kato, S, Takahashi, K, Eifuku, S, Maejima, Y, Shimomura, K, Mizuma, H, Mawatari, A, Doi, H, et al. Chemogenetic activation of mammalian brain neurons expressing insect Ionotropic Receptors by systemic ligand precursor administration. Communications Biology. 2024. 7. 547
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Matsushita, N, Nishizawa, K, Kato, S, Iguchi, Y, Fukabori, R, Takeuchi, K, Miyasaka, Y, Mashimo, T, Kobayashi, K. Catecholaminergic cell type-specific expression of Cre recombinase in knock-in transgenic rats generated by the Combi-CRISPR technology. Journal of Neuroscience Methods. 2022. 381. 109707-109707
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Fukabori, R, Iguchi, Y, Kato, S, Takahashi, K, Eifuku, S, Tsuji, S, Hazama, A, Uchigashima, M, Watanabe, M, Mizuma, H, et al. Enhanced retrieval of taste associative memory by chemogenetic activation of locus coeruleus norepinephrine neurons. The Journal of Neuroscience. 2020. 40. 43. 8367-8385
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MISC (12):
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井口善生, 小林和人. 昆虫におい受容体を用いた哺乳類脳神経細胞のリモート活性化技術における嗅物質の脳移行性の改善. 2024
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Yoshio Iguchi, Richard Benton, Kazuto Kobayashi. A new chemogenetic system using Ionotropic Receptors from the fruit fly Drosophila melanogaster. Springer Nature Research Communities, Behind the Paper (Published in Neuroscience). 2024
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Y Iguchi, K Kobayashi. Chemogenetic activation of target neurons expressing insect Ionotropic Receptors in the central nervous system by systemic administration of ligand precursors. Mendeley Data. 2024
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Iguchi Y, Fukabori R, Kato S, Takahashi K, Eifuku S, Maejima Y, Shimomura K, Mzuma H, Mawatari A, Doi H, et al. Chemogenetic activation of target neurons expressing insect Ionotropic Receptors in the mammalian central nervous system by systemic administration of ligand precursors. bioRxiv. 2023
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Natsuki Matsushita, Kayo Nishizawa, Shigeki Kato, Yoshio Iguchi, Ryoji Fukabori, Kosei Takeuchi, Yoshiki Miyasaka, Tomoji Mashimo, Kazuto Kobayashi. Catecholaminergic cell type-specific expression of Cre recombinase in knock-in transgenic rats generated by the Combi-CRISPR technology. bioRxiv. 2022
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Books (5):
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動物心理学入門 : 動物行動研究から探るヒトのこころの世界 小川園子・富原一哉・岡田隆(編)
有斐閣 2023 ISBN:9784641174887
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Optogenetics. Advances in Experimental Medicine and Biology, vol 1293
Springer, Singapore 2021
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あの人はどうしてそうしてしまうの?身近な7つの扉から入る心理学の世界 羽成隆司(編)・河野和明(編)
ポラーノ出版 2018 ISBN:4908765111
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行動生物学辞典
東京化学同人 2013 ISBN:9784807908370
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心理学へのファーストステップ 羽成隆司(編)・河野和明(編)
おうふう 2008 ISBN:4892429317
Lectures and oral presentations (27):
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昆虫がにおいを感じる仕組みに学ぶほ乳類神経活動の活性化戦略
(2024年度積水化学・自然に学ぶ研究助成 オンライン技術交流会 2024)
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Dopaminergic circuit mechanisms originated in the ventral tegmental area in the regulation of motivation for goal-directed behavior
(The 46th annual Meeting of the Japan Neuroscience Society Simposium 1S04a (Shedding new light on the implications of dopamine in normal brain functions and diseases) (co-organizer with Dr. Louis-Eric Trudeau) 2023)
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Mereology for the basal ganglia
(2023)
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Role of D2 receptor-positive ventral tegmental area dopamine neurons in effort-related motivation for food-seeking
(Dopamine 2022 2022)
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A neuro-mereology starting from the striatum to understand the neural processes supporting trial-and-error-based memory acquisition and habit formation
(The 99th Annual Meeting of the Physiological Society of Japan 2022)
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Professional career (1):
Work history (8):
- 2017/04 - 現在 Institute of Biomedical Sciences, Fukushima Medical University School of Medicine Department of Molecular Genetics Assistant Professor
- 2015/04 - 2017/03 Institute of Biomedical Sciences, Fukushima Medical University School of Medicine Department of Molecular Genetics Research Assistant Professor
- 2010/04 - 2015/03 Kanazawa University Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Medicine
- 2011/04 - 2013/03 Kanazawa University Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Medicine
- 2009/04 - 2010/03 Kanazawa Institute of Technology Research Laboratory for Affective Design Engineering
- 2008/10 - 2009/03 Kanazawa University Institute of Human and Social Sciences
- 2007/04 - 2008/09 Kanazawa University Graduate School of Human and Socio-Environment Studies
- - 2007/03 Nagoya University Graduate School of Environmental Studies, Department of Social and Human Environment
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Association Membership(s) (4):
Society for Neuroscience
, 日本神経科学学会
, 日本動物心理学会
, 日本心理学会
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