Job title：
Associate Professor
Research theme for competitive and other funds (9)：
2022 - 2025 獲得免疫誘導能を有するSV40 VLPがんワクチンの効能解析
2021 - 2022 口腔扁平苔癬モデル動物の確立とdopamineシグナル制御治療薬の開発
2019 - 2022 SV40 VLP免疫活性化剤による免疫活性化と獲得免疫誘導機構の解明
2016 - 2019 Characterization of induction of mucosal immune responses by protein nano-capsule
2014 - 2016 薬剤を用いた自己免疫性炎症反応の解明
2014 - 2016 抗ウイルス細胞傷害性T細胞誘導剤の作用機序の解明及びその応用
2012 - 2015 Basic study of a bionanodevice for medical application and expansion for its use.
2012 - 2014 development of the universal inducing agent for induction of antivirus cytotoxic T lymphocytes
2011 - 2014 Development of a novel vaccine carrier for the next-generation influenza universal vaccine
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Papers (51)：
Masaaki Kawano, Rie Takagi, Mieko Tokano, Sho Matsushita. Adenosine induces IL-31 secretion by T-helper 2 cells: Implication for the effect of adenosine on atopic dermatitis and its therapeutic strategy. Biochemical and Biophysical Research Communications. 2023. 645. 19. 47-54
Yuta Isozaki, Tsuyoshi Sato, Rie Takagi, Ko Ito, Michihiko Usui, Masaaki Kawano, Sho Matsushita. Ropinirole inhibits inflammatory cytokine production in gingival epithelial cells and suppresses alveolar bone loss in an experimental rat model of periodontitis. Experimental and Therapeutic Medicine. 2022. Article Number 78, 2022
Mieko Tokano, Sho Matsushita, Rie Takagi, Toshimasa Yamamoto, Masaaki Kawano. Extracellular adenosine induces hypersecretion of IL-17A by T-helper 17 cells through the adenosine A2a receptor. Brain, Behavior, & Immunity - Health. 2022. 26. December 2022. 100544-100544
Mieko Tokano, Masaaki Kawano, Rie Takagi, Sho Matsushita. Istradefylline, an adenosine A2a receptor antagonist, inhibits the CD4+T-cell hypersecretion of IL-17A and IL-8 in humans. Immunological Medicine. 2022. 45. 4. 244-250
Mieko Tokano, Rie Takagi, Masaaki Kawano, Shigefumi Maesaki, Norihito Tarumoto, Sho Matsushita. Signaling via dopamine and adenosine receptors modulate viral peptide-specific and T-cell IL-8 response in COVID-19. Immunological Medicine. 2022. 45. 3. 162-167
Development of surface-modified magnetic nanoparticles for medical applications.,Magnetic Nanoparticles for Medical Diagnostics.
Institute of Physics Publishing 2018
Chapter 5, Development of surface-modified magnetic nanoparticles for medical applications.,Magnetic Nanoparticles for Medical Diagnostics.
Institute of Physics Publishing 2018
Chapter 5, Development of surface-modified magnetic nanoparticles for medical applications. Magnetic Nanoparticles for Medical Diagnostics.
Institute of Physics Publishing 2018
Dopamine fluctuates cytokine secretion in innate and adaptive immune responses
(The 46th Annual Meeting of The Japanese Society for Immunology, 2017 2017)
2003 - 2006 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology Department of Biological Information
2001 - 2003 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology Department of Biological Information
1997 - 2001 Tokyo Institute of Technology Faculty of Bioscience and Biotechnology
Professional career (3)：
Ph.D (Tokyo Institute of Technology)
修士 (工学) (東京工業大学)
工学博士 (東京工業大学)
Work history (2)：
2014/09 - 2017/09 Tokyo Medical University Department of Nanoparticle Translational Research Part-time researcher for university or other academic organization
2014/09 - 2017/09 Tokyo Medical University Department of Nanoparticle Translational Research Visiting Associate Professor
Committee career (8)：
2022/04 - 現在 埼玉医科大学中央研究施設機能部門 中央研究施設機能部門副部門長(兼担)
2019/09/01 - 現在 図書館委員 委員
2019/09 - 現在 埼玉医科大学図書館委員会 委員
2019/04 - 現在 埼玉医科大学動物実験委員会 委員
2016/04 - 現在 埼玉医科大学中央研究施設管理運営委員会 委員
2022/10 - 2024/10 Representative
2021/06/20 - 2022/10/07 日本アレルギー学会 代議員
2021/06 - 2022/10 Japanese Society of Allergology Representative
2009/04 - Cancer Center Support Grant award by the UC Davis
2007/11 - Postdoctoral fellowship of Uehara memorial foundation for studying abroad
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Association Membership(s) (6)：
The Japanese Biochemical Society
, Japanese Society for Chemical Biology
, Japanese Society of Allergology
, Japanese Association of Cancer Immunology
, Japanese Society for Immunology
, The Japanese Society for Virology
