Rchr
J-GLOBAL ID:201101055698898629
Update date: Jul. 05, 2024
Kubo Ken-ichiro
クボ ケンイチロウ | Kubo Ken-ichiro
Affiliation and department:
Job title:
Professor
Homepage URL (1):
http://www.jikei.ac.jp/academic/course/02_sokaibo.html
Research field (4):
Psychiatry
, Neuroscience - general
, Neuroanatomy and physiology
, Fetal medicine/Pediatrics
Research keywords (31):
大脳
, 神経細胞
, 神経細胞移動
, 新皮質
, 子宮内胎児電気穿孔法
, Reelin
, 層構造
, マウス
, RNAi法
, 細胞移動
, 移動
, 脳神経疾患
, 動物モデル
, 病理学
, 脳・神経
, 未熟児医学
, 包括脳ネットワーク
, 精神・神経疾患
, Dab1
, 子宮内電気穿孔法
, 海馬
, 発生
, 統合失調症
, 精神疾患
, 中枢神経系
, disrupted in schizophrenia 1 (DISC1)
, 双極性感情障害
, Bardet-Biedl syndrome
, 大脳皮質
, 脳の発生
, DISC1
Research theme for competitive and other funds (18):
- 2022 - 2026 個細胞空間的degradome解析に基づくプロテアーゼを介したがん免疫制御の解明
- 2021 - 2026 Elucidation of pathological mechanisms of neuropsychiatric disorders by analyses of postmortem brains
- 2020 - 2023 Effects of in utero environment on pathogenesis of neurodevelopmental disorders
- 2019 - 2022 Effects of calorie restriction in utero on cerebral cortical histogenesis and postnatal behavior
- 2019 - 2022 発達期ダイオキシンと老年期の高次認知機能低下の関係性解明
- 2019 - 2021 Analysis of pathological mechanisms of neuropsychiatric disorders associated with cytoarchitectural changes
- 2018 - 2021 Investigation of molecular change in the white matter neurons
- 2018 - 2021 Analysis of pathological mechanism of cognitive impairment and neurodevelopmental disorder observed in the new model mouse of extremely preterm infants
- 2016 - 2019 Effects of calorie restriction in utero on cerebral cortical histogenesis
- 2015 - 2018 Investigation of the mechanism of ischemic brain injury in extremely preterm infants
- 2014 - 2018 Analysis of molecular mechanisms that regulate neocortical layer structure formation
- 2016 - 2017 Mechanisms of neuronal cell death and survival
- 2015 - 2017 微細な組織構築変化をマイクロエンドフェノタイプとする精神神経疾患の病態解明
- 2012 - 2016 Establishment and analysis of a new mouse model of ischemic brain injuries in extremely preterm infants
- 2013 - 2015 微細な組織構築の異常をマイクロエンドフェノタイプとした精神病態の解明
- 2011 - 2013 The analyses of molecular mechanisms that regulate brain cortical development
- 2009 - 2011 Pathological study of higher brain dysfunction as a neurological outcome in extremely preterm infants
- 2007 - 2008 Analysis of the function of DISC1 to understand the pathology of schizophrenia
Show all
Papers (53):
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Julio Leon, Satoshi Yoshinaga, Mizuki Hino, Atsuko Nagaoka, Yoshinari Ando, Jonathan Moody, Miki Kojima, Ayako Kitazawa, Kanehiro Hayashi, Kazunori Nakajima, et al. Integrative Transcriptomics Reveals Layer 1 Astrocytes Altered in Schizophrenia. 2024
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Sarasa Yano, Natsu Asami, Yusuke Kishi, Hikari Kubotani, Yuki Hattori, Ayako Kitazawa, Kanehiro Hayashi, Ken-ichiro Kubo, Mai Saeki, Chihiro Maeda, et al. Propagation of neuronal micronuclei regulates microglial states. 2023
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Kota Oshima, Satoshi Yoshinaga, Ayako Kitazawa, Yuki Hirota, Kazunori Nakajima, Ken-Ichiro Kubo. A Unique "Reversed" Migration of Neurons in the Developing Claustrum. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023. 43. 5. 693-708
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Satoshi Yoshinaga, Takao Honda, Ken-Ichiro Kubo, Kazunori Nakajima. Dab1-deficient deep layer neurons prevent Dab1-deficient superficial layer neurons from entering the cortical plate. Neuroscience research. 2022
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Debabrata Hazra, Satoshi Yoshinaga, Keitaro Yoshida, Norio Takata, Kenji F Tanaka, Ken-Ichiro Kubo, Kazunori Nakajima. Rhythmic activation of excitatory neurons in the mouse frontal cortex improves the prefrontal cortex-mediated cognitive function. Cerebral cortex (New York, N.Y. : 1991). 2022
more...
MISC (27):
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竹内 章人, 高橋 立子, 永田 雅子, 福井 美保, 荒井 洋, 城所 博之, 出口 貴美子, 久保 健一郎, 井上 健, 森岡 一朗. 日本新生児成育医学会推薦総説 超早産児における神経発達症の臨床像とその病態. 日本小児科学会雑誌 = The journal of the Japan Pediatric Society. 2019. 123. 4. 661-673
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Analysis of the association of impaired neuronal migration with cognitive impairments in extremely preterm infants. Japanese Journal of Cognitive Neuroscience. 2019. 21. 2. 127-127
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吉永怜史, 久保健一郎, 仲嶋一範. 精神科医でもある大学院生が行っている神経発生研究. 日本生物学的精神医学会誌. 2019. 30. 3. 120-125
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Kanehiro Hayashi, Ayako Kitazawa, Ken-ichiro Kubo, Yuki Matsunaga, Kazuhiro Ishii, Kazunori Nakajima. Climbing mode of migration: A novel migration mode of pyramidal neurons in the developing hippocampus. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE. 2015. 47. 49-49
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Kazunari Yoshida, Yasushi Imasaka, Ken-ichiro Kubo, Takefumi Suzuki, Masaru Mimura, Hiroyuki Uchida. Resilience in Patients with Schizophrenia: A Comparative Study between a Distant Island and an Urban Area. BIOLOGICAL PSYCHIATRY. 2015. 77. 9
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Professional career (1):
Work history (4):
- 2021 - 現在 The Jikei University School of Medicine
- 2017 - 2021 Keio University School of Medicine
- 2012 - 2017 Keio University School of Medicine
- 2007 - 2012 Keio University School of Medicine
Association Membership(s) (7):
Society for Neuroscience
, 日本生物学的精神医学会
, 日本解剖学会
, 日本神経科学会
, 日本神経化学会
, 日本小児神経科学会
, 日本精神神経学会
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