Nakajima Hisakazu

ナカジマヒサカズ | Nakajima Hisakazu

Affiliation and department：

Research field (6)： Molecular biology , Home economics, lifestyle science , Early childhood education and childcare , Nutrition and health science , Fetal medicine/Pediatrics , Metabolism and endocrinology

Research keywords (16)： Leptin melanocortin hypothalamic pathway and the control of apptite , Clinical Genetics , Ghrelin and Ghrelin receptor , Food preference and eating behavior , エネルギー代謝 , 国際情報交換 , Energy expenditure , Pediatric diabetes , Pediatric obesity , Inherited metabolic disease , Pediatric endocrinology , Clinical Nutrition , Nutrition , 小児肥満 , 先天代謝異常 , 小児内分泌学

Research theme for competitive and other funds (8)：

2021 - 2024 Targeted exome analysis as a diagnostic tool for the leptin-melanocortin pathway related genes in childhood obesity
2020 - 2023 ACE2/Ang1-7系のDNAメチル化を介した褐色脂肪細胞分化機構の解明
2018 - 2021 The study on relationships between CLOCK gene polymorphism and childhood obesity
2015 - 2018 The relationships between the genetic polymorphisms of FTO gene and childhood obesity
2015 - 2018 Investigation of an anti-obesity effect of Ang 1-7 via activation of brown adipocyte

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Papers (61)：

杉本哲, 西田望, 宮垣知史, 河辺泰宏, 中島久和, 篠原正和, 家原知子. エリスロポエチンの抗肥満・抗糖尿病作用の機序解明. 日本小児科学会雑誌. 2024. 128. 2. 188-188
中島久和, 宮垣知史, 河辺泰宏, 杉本哲. 小児期発症肥満におけるレプチン・メラノコルチン系遺伝子のバリアント検出の試み. 肥満研究. 2023. 29. 合同学術集会抄録集. 318-318
杉本哲, 中島久和. 最先端医療の今ミグリトールの褐色脂肪組織を介した抗肥満効果. Medical Science Digest. 2023. 49. 11. 600-601
Miglitol has anti-obesity effects though the brown adipose tissue. Medical Science Digest. 2023. 49. 11. 32-33
Hisakazu Nakajima. Genetic anlaysis of childhood obesity using the genes related to leptin-melanocortin signaling pathway. Medical Science Digest. 2023. 49. 8. 444-447

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MISC (118)：

中島久和, 山口美穂子, 森潤, 森元英周, 河辺泰宏, 杉本哲, 木崎善郎. PHEXに新規病的バリアントを認めた遺伝性低リン血性くる病の1例. 日本内分泌学会雑誌. 2022. 98. 2. 625-625
中島久和, 森元英周, 幸道和樹, 杉本哲. KCNQ1遺伝子変異による歯肉線維腫症を合併した成長ホルモン分泌不全性低身長症の1例. 日本内分泌学会雑誌. 2022. 98. 1. 339-339
中島久和, 福原正太, 森潤. テストステロン治療にて肥満症の改善をみた思春期クラインフェルター症候群. 肥満研究. 2022. 27. Suppl. 341-341
中島久和, 福原正太, 森潤. テストステロン治療にて肥満症の改善をみた思春期クラインフェルター症候群. 肥満研究. 2022. 27. Suppl. 341-341
山口美穂子, 森潤, 西田望, 宮垣知史, 太田武志, 河辺泰宏, 森元英周, 中島久和, 家原知子. 母胎高脂肪食負荷による胎仔発育不全と非震え熱産生臓器褐色脂肪への影響の解明. 日本小児科学会雑誌. 2022. 126. 2. 359-359

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Books (1)：

最新子ども保健
日本小児医事出版社 2017 ISBN:9784889242553

Lectures and oral presentations (29)：

小児肥満における摂食抑制系遺伝子を中心としたエクソーム解析の試み.
(第37回日本小児脂質研究会 2023)
小児期発症肥満におけるレプチン・メラノコルチン系遺伝子のバリアント検出の試み.
(第44回日本肥満学会・第41回日本肥満症治療学会合同学術集会 2023)
Anti-obesity effect via thermogenesis of recombinant human angiotensin converting enzyme 2 (rhACE2): Effect on differentiation of brown adipose tissue and browning white adipose tissue
(The 54th Annual Scientific Meeting of the Japanese Society for Pediatric Endocrinology 2021)
Examination of regional differences in nutrition of children with short stature living in the same prefecture
(The 54th Annual Scientific Meeting of the Japanese Society for Pediatric Endocrinology 2021)
The first case repotr identified in Japan on combined pituitary hormone deficiency caused by the mutation of KCNQ1 genee
(The 54th Annual Scientific Meeting of the Japanese Society for Pediatric Endocrinology 2021)

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Education (2)：

1999 - 2003 Kyoto Prefectural University of Medicine Graduate School Medical Science/ Department of Pediatrics
1989 - 1995 Osaka Medical College School of Medicine Department of Medicine (six-year system)

Professional career (1)：

医学博士 (京都府立医科大学)

Work history (8)：

2021/04 - 現在 Kyoto Prefectural University of Medicine Department of Pediatrics Specially Appointed Lecturer
2021/04 - 現在 Midorigaoka Hospital Department of Pediatrics Directer
2017/04 - 2021/03 Graduate School Kyoto Prefectural University of Medicine Department of Pediatrics Lecturer
2017/04 - 2021/03 North Medical Center Kyoto Prefectural University Hospital Department of Pediatrics Lecturer
2013/04 - 2017/03 Kyoto Prefectural University of Medicine Department of Pediatrics Assistant professor

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Committee career (20)：

2024/04 - 現在 The Japan Endocrine Society Councilor
2024/01 - 現在 Japan Society for the Study of Obesity (JASSO) Obesity specialist of medicine
2022/07 - 現在日本頭痛学会会員
2021/04 - 現在成長科学協会地区委員
2018/04 - 現在日本内分泌学会内分泌代謝専門医(小児科)

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Awards (8)：

2018/09 - Japanese Society of Pediatric Endocrinology The Japanese Society for Pediatric Endocrinology Future Development Grant supported by Novo Nordisk Pharma Ltd. The important role of the MeCP2 gene in eating behavior and food preference
2017/08 - 京都府公立大学法人平成29年度京都府地域未来づくり支援事業小児肥満における時計遺伝子CLOCKの遺伝子多型の影響の研究
2016/11 - The 9th Meeting of Asia-Pacific Pediatric Endocrinology Society High-score Poster Award Erythropoietin ameliorates obesity and glucose intolerance on high fat dietary obese mice through the activation of erythropoietin receptor/STAT3 pathway and the up-regulation of FGF21 secretion on classical brown adipose tissue
2016/09 - The 55th Meeting of European Society for Paediatric Endocrinology President Poster Award The collapse of BDNF/POMC system is responsible for the extreme obesity with hyperphagia in female MeCP2 knockout mice fed with high-fat diet.
2014/08 - 京都府公立大学法人平成26年度京都府地域関連課題等研究支援事業新生児マススクリーニング(タンデムマス法)で発見された脂肪酸代謝異常症の遺伝子診断

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Association Membership(s) (15)：

THE JAPAN SOCIETY OF HUMAN GENETICS , The Japan Society of Pediatrics , JAPANESE SOCIETY ON SEVERE MOTOR AND INTELLECTUAL DISABILITIES , APPES , JAPANESE SOCIETY FOR PARENTERAL AND ENTERAL NUTRITION , THE JAPAN DIABETES SOCIETY , 日本ステロイドホルモン学会 , 日本甲状腺学会 , JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE , JAPANESE SOCIETY FOR PEDIATRIC GASTROENTEROLOGY, HEPATOLOGY AND NUTRITION , 日本肥満症治療学会 , JAPAN SOCIETY FOR THE STUDY OF OBESITY , JAPANESE SOCIETY FOR INHERITED METABOLIC DISEASES , THE JAPANESE SOCIETY FOR PEDIATRIC ENDOCRINOLOGY , THE JAPAN ENDOCRINE SOCIETY

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