Rchr
J-GLOBAL ID：201101062786787183   Update date: Apr. 14, 2024

Shimada Hitoshi

シマダ ヒトシ | Shimada Hitoshi
Affiliation and department：
Niigata University Brain Research Institute Center for Integrated Human Brain Science Department of Functional Neurology and Neurosurgery

About Niigata University Brain Research Institute Center for Integrated Human Brain Science Department of Functional Neurology and Neurosurgery


Job title： Professor
Other affiliations (1)：
  • National Institutes for Quantum and Radiological Science and Technology  Visiting researcher
Homepage URL  (1)： https://nrid.nii.ac.jp/ja/nrid/1000010422239/
Research field  (3)： Radiology ,  Neuroscience - general ,  Neurology
Research keywords  (21)： neurodegenerative disease ,  lysosome ,  TMEM106B ,  α-synuclein ,  tau ,  amyloid ,  acetylcholinesterase ,  acethylcholine ,  PET ,  dementia ,  Lewy body diseases ,  Parkinson's disease ,  PSP ,  CBD ,  dementia with Lewy bodies ,  Alzheimer's disease ,  FTD ,  FTLD ,  REM behavior disorder ,  VBM (voxel-based morphometry) ,  cognitive function
Research theme for competitive and other funds  (9)：
  • 2018 - 2023 PET evaluation of pathological diversity in dementia towards the establishment of novel diagnostic and therapeutic strategies
  • 2017 - 2020 Evaluation of tau accumulation with PBB3-PET in amyloid negative dementia patients
  • 2016 - 2019 Evaluation of tau protein related neural dysfunction: PET and 3T MRS study
  • 2015 - 2018 The relationship between tau accumulation and BPSD in Alzheimer disease: a tau PET imaging study
  • 2014 - 2018 Tau PET study for revealing the pathogenesis and establishing the objective marker of disease severity in neurodegenerative dementia
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Papers (186)：
  • Hiroyuki Morino, Takashi Kurashige, Yukiko Matsuda, Maiko Ono, Naruhiko Sahara, Tomohiro Miyasaka, Yoshiyuki Soeda, Hitoshi Shimada, Yu Yamazaki, Tetsuya Takahashi, et al. Clinical and Pathological Features of FTDP-17 with MAPT p.K298_H299insQ Mutation. Movement disorders clinical practice. 2024
  • Manabu Kubota, Hironobu Endo, Keisuke Takahata, Kenji Tagai, Hisaomi Suzuki, Mitsumoto Onaya, Yasunori Sano, Yasuharu Yamamoto, Shin Kurose, Kiwamu Matsuoka, et al. In vivo PET classification of tau pathologies in patients with frontotemporal dementia. Brain Communications. 2024
  • Kiwamu Matsuoka, Kosei Hirata, Naomi Kokubo, Takamasa Maeda, Kenji Tagai, Hironobu Endo, Keisuke Takahata, Hitoshi Shinotoh, Maiko Ono, Chie Seki, et al. Investigating neural dysfunction with abnormal protein deposition in Alzheimer's disease through magnetic resonance spectroscopic imaging, plasma biomarkers, and positron emission tomography. NeuroImage. Clinical. 2023. 41. 103560-103560
  • Kosei Nakamura, Yasuko Kuroha, Masahiro Hatakeyama, Atsushi Michael Kimura, Yukimi Nakamura, Yoshihiro Murakami, Masaki Watanabe, Hironaka Igarashi, Tetsuya Takahashi, Hitoshi Shimada. Corticobasal syndrome mimicking Foix-Chavany-Marie syndrome with suggested 4-repeat tauopathy by tau PET. BMC geriatrics. 2023. 23. 1. 838-838
  • 小久保 奈緒美, 遠藤 浩信, 互 健二, 平田 浩聖, 松岡 究, 片岡 優子, 大矢 雅樹, 松元 秀樹, 黒瀬 心, 市橋 雅典, et al. PCA単一症例の縦断評価によるタウ病理と認知機能障害の検討. Dementia Japan. 2023. 37. 4. 660-660
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MISC (136)：
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Professional career (1)：
  • M.D., Ph.D. (千葉大学大学院医学研究院)
Work history (7)：
  • 2021/04 - 現在 National Institutes for Quantum and Radiological Science and Technology Visiting researcher
  • 2021/04 - 現在 Niigata University Brain Research Institute Center for Integrated Human Brain Science Department of Functional Neurology and Neurosurgery Professor
  • 2017/07 - 2021/03 National Institutes for Quantum and Radiological Science and Technology Principal researcher
  • 2015/04 - 2017/06 国立研究開発法人放射線医学総合研究所 主任研究員
  • 2014/07 - 2015/03 National Institutes for Quantum and Radiological Science and Technology
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