Yokoya Akinari

Yokoya Akinari | Yokoya Akinari

Affiliation and department：
Job title： Senior Expert
Other affiliations (1)：

Ibaraki University Graduate School of Science and Engineering Major in Quantum Beam Science Professor

Homepage URL (1)： https://www.qst.go.jp/site/iqls/

Research field (2)： Biophysics , Environmental effects of chemicals

Research keywords (8)： Quantum Life Science , Systems biology , Synchrotron radiation , Physicochemical processes of DNA damage , Clustered DNA damage , DNA repair , radiation damage to DNA , 放射線生物物理学

Research theme for competitive and other funds (25)：

2019 - 2025 Compound activation in the human body using light(Research Director: Mikako Ogawa)
2020 - 2024 Quantum mechanism and regulation of radiation damage to DNA
2020 - 2023 Biological Significance of DNA-PK in the Orchestration of Cellular Response to DNA Double-strand Breaks
2018 - 2022 Role of Hydration Water in Radiation Damage to DNA
2016 - 2019 Systems biology for cellular responses to radiation stress

2015 - 2018 Mechanism of cluster DNA damage induction and its repair processes in vivo

2015 - 2017 Explore of molecular aerials sensitizing radiobiological effects

2013 - 2016 Development of a spectroscopic study for radiation damage induction by thermal relaxation

2013 - 2015 Synergy effect of subcellular organelles in radiation responses

2012 - 2015 Control of Biological Effect by Altered ATP induced with Synchrotron Soft X-rays

2010 - 2015 Research on molecular structure and repair of complex DNA damage

2012 - 2014 Study of Biological Effect induced by Radiation Damage of non-DNA Molecules

2009 - 2014 Study of radiation-induced cluster DNA damage- its structure and repair susceptibility

2012 - 2014 放射光軟X線を用いたATP分子変異の誘発による生物効果の制御

2010 - 2014 複雑損傷の分子構造と修復に関する研究

2012 - 2013 非DNAに対する放射線損傷に伴う生物影響の検討

2009 - 2013 放射線によるクラスターDNA損傷の構造と難修復特性の研究

2011 - 2012 Non-linear DNA repair responses caused by interference between competitive repair pathways

2009 - 2011 DEVELOPMENT OF A TIME-DEPENDENT LIQUID MICRO-JET SPECTROSCOPY FOR RADIATION-INDUCED ANORMALY IN MIMETIC BIO-CELL MOLECULES

2007 - 2009 Isolation of repair-deficient mutants for clustered DNA damage

2006 - 2008 Physicochemical and biochemical study of radiation induced DNA damage

2005 - 2007 Development of a Time Correlation Spectroscopy for Liquid Phase Reactions using a Liquid Micro Jet in Combination with a Synchrotron Radiation

2003 - 2005 シンクロトロン放射を用いた放射線DNA損傷の分光学的研究

2001 - 2003 Synchrotron-Radiation Electron-Spectroscopy for Chemical Analysis on molecules in solution

1995 - 1996 Development of an irradiation system of monochromatic photons (50-1000 eV) for wet biological samples

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Papers (148)：

Tomohiro Toigawa, Takeshi Kai, Yuta Kumagai, Akinari Yokoya. Consideration of the dielectric response for radiation chemistry simulations. The Journal of chemical physics. 2024. 160. 21
Marie-Anne Hervé du Penhoat, Alexandre Souchaud, Aashini Rajpal, Rodolphe Vuilleumier, Marie-Pierre Gaigeot, Ivano Tavernelli, Kentaro Fujii, Akinari Yokoya, Sergio Díaz-Tendero, Marie-Françoise Politis. Ultrafast fragmentation of highly-excited doubly-ionized deoxyribose: role of the liquid water environment. Physical chemistry chemical physics : PCCP. 2024. 26. 21. 15693-15704
Maki Ohara, Yudai Izumi, Hideo Takakura, Shosei Enomoto, Kentaro Fujii, Akinari Yokoya, Mikako Ogawa. Decomposition characteristics of a hypervalent iodine compound, 2-iodosobenzoic acid, exposed to monochromatic X-rays around the iodine L3-edge energy region. Radiation Physics and Chemistry. 2024. 216. 111394-111394
Yudai Izumi, Maki Ohara, Kentaro Fujii, Akinari Yokoya, Mikako Ogawa. X-ray photoemission and absorption spectroscopy of a hypervalent iodine compound, 2-iodosobenzoic acid. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 2024. 547. 165211-165211
S. Onuma, Y. Izumi, M. Ohara, A. Yokoya. Electronic states of fluorinated DNA components revealed by X-ray photoelectron spectroscopy. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 2024

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MISC (440)：

中川清子, 横谷明徳, 大原麻希, 宇佐美徳子, 浅田瑞枝, 藤原基靖, 中村敏和, 石川健治. ESR imaging of radicals produced in alanine by soft X-ray irradiation. 電子スピンサイエンス学会年会講演要旨集. 2023. 62nd (CD-ROM)
永田健斗, 西村まゆみ, 臺野和広, 臺野和広, 飯塚大輔, 飯塚大輔, 西村由希子, 西村由希子, 服部佑哉, 渡邊立子, et al. Analysis of early cellular dynamics leading to radiation carcinogenesis in rat mammary gland. 日本癌学会学術総会抄録集(Web). 2023. 82nd
小沼草太, 大原麻希, 横谷明徳, 横谷明徳. Electric properties of fluorinated DNA related molecules revealed by XPS. KEK Progress Report (Web). 2023. 2023-2
西村由希子, 神長輝一, 宇佐美徳子, 横谷明徳, 今岡達彦. Does sparse radiation exposure affect rat mammary cell competition?. KEK Progress Report (Web). 2023. 2023-2
小畑結衣, 小畑結衣, 木名瀬暁理, 横谷明徳, 横谷明徳. EGFP plasmid DNA damage induced by phosphorus K-resonance excitation and its cellular repair. 量子ビームサイエンスフェスタ(Web). 2023. 2022

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Books (1)：

Charged particle and photon interactions with matter-recent advances, applications and interfaces
CRC/Taylor & Francis Group 2011

Lectures and oral presentations (12)：

Novel sciences of raddiation biology using two beams (Radiation Biology User Group)
(Beamline for R&D: Construction and Use 2023)
Radiation damage processes explored based on physical property of electronic states of biological molecules
(2022)
Clustered DNA damage
(Workshop on Auger Therapy 2022)
Exploring active structures of DNA repair protein XRCC4 using CD and SAXS
(The 26th Hiroshima International Symposium on Synchrotron Radiation 2022)
Chemical repairing effects of additives on early radiation-induced DNA damage
(2021)

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Education (4)：

1992 - University of Tsukuba
1987 - 1991 Tsukuba University
1985 - 1987 Tsukuba University
1981 - 1985 Tsukuba University

Professional career (1)：

博士(理学) (筑波大学)

Work history (12)：

2022/04 - 現在 National Institutes for Quantum Science and Technology Institute for Quantum Life Science, Quantum Life and Medical Science Directorate Senior Expert
2021/04 - 現在 Ibaraki University Graduate School of Science and Engineering Major in Quantum Beam Science Professor by cross-appointment system
2021/06 - 2022/03 National Institutes for Quantum Science and Technology Institute for Quantum Life Science, Quantum Life and Medical Science Directorate Senior principal researcher
2019/04 - 2021/03 National Institutes for Quantum and Radiological Science and Technology Institute for Quantum Life Science Senior Principal Researcher
2010/04 - 2021/03 Ibaraki University Graduate School of Science and Engineering

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Committee career (2)：

2024/04 - 現在 PF User association Strategic and Future Planning Subcommittee
2012 - 現在 Photon Factory User Association PF-UA 運営委員

Awards (4)：

2022/06 - 日本アイソトープ協会第26回RADIOISOTOPES誌論文奨励賞マウス精巣器官培養法を活用した放射線不妊メカニズムの解析
2020/12 - Quantum Life Science Society award of excellent presentation Development of Ca ion dynamics in mammalian cells under stress of X-irradiation
2020/10 - The Japanese Radiation Research Society The Japanese Radiation Research Society Distinguished Scientist Award
2019/05 - Quantum Life Science Society award of excellence Study of process of DNA repair protein (XRCC4) complex formation using X-ray small angle scattering

Association Membership(s) (5)：

PF-User Association , Quantum Life Science Society , JAPANESE SOCIETY OF RADIATION CHEMISTRY , THE JAPANESE RADIATION RESEARCH SOCIETY , THE JAPANESE SOCIETY FOR SYNCHROTRON RADIATION RESEARCH

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