Research keywords (5):
Human genome diversity
, Crohn's disease
, Evolutionary medicine
, Complex diseases
, Human evolution
Research theme for competitive and other funds (6):
2022 - 2027 Elucidating the dynamics of the Copan dynasty in the Maya civilization through paleogenomics
2022 - 2025 Population genomics of Jomon: elucidating adaptive evolution in ancient hunters and gatherers and its legacy in modern populations
2020 - 2025 パレオゲノミクス解析プラットフォーム開発とその応用
2021 - 2024 シン・パレオゲノミクスが創る博物館資料群活用の新展開
2020 - 2022 Identifying shifts in selective pressures driven by environmental and cultural changes: Population genomics modelling on ancient and modern Maya
2019 - 2022 Applying temporal and spatial population genetics modelling for the origins of modern Japanese
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Papers (33):
Juhyeon Lee, Takehiro Sato, Atsushi Tajima, Tsend Amgalantugs, Batmunkh Tsogtbaatar, Shigeki Nakagome, Toshihiko Miyake, Noriyuki Shiraishi, Choongwon Jeong, Takashi Gakuhari. Medieval genomes from eastern Mongolia share a stable genetic profile over a millennium. Human Population Genetics and Genomics. 2024. 4. 1. 0004
Takashi Gakuhari, Shigeki Nakagome, Simon Rasmussen, Morten E. Allentoft, Takehiro Sato, Thorfinn Korneliussen, Blánaid Ní Chuinneagáin, Hiromi Matsumae, Kae Koganebuchi, Ryan Schmidt, et al. Ancient Jomon genome sequence analysis sheds light on migration patterns of early East Asian populations. Communications Biology. 2020. 3. 1
Shigeki Nakagome. Genomic profiling of intestinal T-cell receptor repertoires in inflammatory bowel disease. Genes & Immunity. 2020
Shigeki Nakagome. The evolving Japanese: the dual structure hypothesis at 30. Evolutionary Human Sciences. 2020
Gakuhari T, Nakagome S, Rasumussen S, Allentoft M, Sato T, Korneliussen T, Chuinneagain BN, Matsumae H, Koganebuchi K, Schmidt R, et al. Jomon genome sheds light on East Asian population history. BioRxiv. 2019
Evolutionary insights into the “population-specificity” of genetic factors associated with inflammatory bowel diseases.
Book Chapter in Ulcerative Colitis from Genetics to Complications Mustafa M. Shennak (Editor) Rijeka: InTech
Lectures and oral presentations (11):
Application of kernel approximate Bayesian computation for population genetic study
(Mathematical Ecology & Evolution seminar in Meiji University Ikuta campus 2012)
Populstion-specific susceptibility of Crohn's disease risk alleles in the NOD2 locus
(The 57th Annual Meeting of The Japan Society of Human Genetics, Tokyo, Japan 2012)
Kernel Bayesian Computation
(XXVIth International Biometric Conference, Kobe, Japan 2012)
Kernel Approximate Bayesian Computation
(Annual Meeting of the Society for Molecular Biology and Evolution, Dublin, Ireland 2012)