Research theme for competitive and other funds (5)：
2019 - 2023 霊長類に対して光遺伝学を応用した神経経路選択的な伝達遮断法を実現する
2016 - 2019 A new artificial scotoma model by optogenetics and neural mechanisms of perceptual filling in
2015 - 2017 光遺伝学を用いた霊長類の視覚-運動変換系の神経経路選択的な伝達遮断法の確立
2014 - 2016 Identification of functional role of neural networks between basal ganglia and cerebral cortex by optogenetics
2013 - 2016 Study about the superior colliculus related neural pathway for blindsight by using new genetic method
Papers (20)：
Tadashi Isa, Takamichi Tohyama, Masaharu Kinoshita. Phylogenetic view of the compensatory mechanisms in motor and sensory systems after neuronal injury. Current Research in Neurobiology. 2022. 3. 100058-100058
Masaharu Kinoshita, Rikako Kato, Kaoru Isa, Kenta Kobayashi, Kazuto Kobayashi, Hirotaka Onoe, Tadashi Isa. Dissecting the circuit for blindsight to reveal the critical role of pulvinar and superior colliculus. Nature Communications. 2019
Hung-Ya Tu, Takehito Watanabe, Hiroshi Shirai, Suguru Yamasaki, Masaharu Kinoshita, Keizo Matsushita, Tomoyo Hashiguchi, Hirotaka Onoe, Take Matsuyama, Atsushi Kuwahara, et al. Medium- to long-term survival and functional examination of human iPSC-derived retinas in rat and primate models of retinal degeneration. EBioMedicine. 2019. 39. 562-574
Hiroshi Shirai, Michiko Mandai, Masaharu Kinoshita, Hirotaka Onoe, Keizo Matsushita, Atsushi Kuwahara, Suguru Yamasaki, Hiroko Terasaki, Yoshiki Sasai, Masayo Takahashi. Transplantation of human induced pluripotent stem cell-derived retinal tissue in primate models of retinal degeneration with perimetric analysis. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2016. 57. 12
伊佐かおる, Thongchai Sooksawate, 松井亮介, 加藤成樹, 木下正治, 小林憲太, 渡邉大, 小林和人, 伊佐正. Selective blockade of crossed tecto-reticular pathway by double infection of viral vectors impaired orienting responses in mice; methodological considerations. 第36回日本神経科学大会・第56回日本神経化学会大会・第23回日本神経回路学会大会合同大会. P1-2-244, 京都. 2013
木下正治, 笠原洋紀, 畑中伸彦, 松井亮介, 知見聡美, 伊佐かおる, 水上浩明, 小澤敬也, 南部篤, 渡邉大, et al. Optogenetic suppression of forelimb muscle activities in the behaving macaque monkey by introduction of microbial opsins in the primary motor cortex. 第36回日本神経科学大会・第56回日本神経化学会大会・第23回日本神経回路学会大会合同大会. P3-2-242, 京都. 2013
當山峰道, 木下正治, 松井亮介, 加藤成樹, 長谷川拓, 笠原洋紀, 伊佐かおる, 渡邉大, 小林和人, 里宇明元, et al. Verified contribution of propriospinal neurons to recovery of hand dexterity after a corticospinal tract lesion in the monkey. 第36回日本神経科学大会・第56回日本神経化学会大会・第23回日本神経回路学会大会合同大会. P1-1-74, 京都. 2013
