Izumi Tomonori

Affiliation and department：

Research field (1)： Structural biochemistry

Research keywords (1)： protein chemistry, proteomics

Research theme for competitive and other funds (16)：

2020 - 2023 漏出細胞内タンパク質の細胞外機能:組織損傷時の貪食細胞への作用と炎症・抗炎症調節
2017 - 2021 A method for analyzing dynamics of post-transcriptional modifications of small amounts of RNA
2017 - 2020 Extracellular function of leaked intracellular proteins: role and action in receptor-sharing monocytes and endothelial cells
2016 - 2018 Pseudouridine: new biomarker for cancer diagnosis
2014 - 2017 Extracellular function of intracellular proteins released from damaged tissue and bound to monocytes.

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Papers (52)：

Yusuke Mimura, Toshihiko Katoh, Radka Saldova, Roisin O’Flaherty, Tomonori Izumi, Yuka Mimura-Kimura, Toshiaki Utsunomiya, Yoichi Mizukami, Kenji Yamamoto, Tsuneo Matsumoto, et al. Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy. Protein and Cell. 2018. 9. 1. 47-62
Akiyoshi Y, Izumi T, Oda Y, Mizukami Y, Tsuruta R, Maekawa T. Analysis of cerebrospinal fluid proteins reveals association of calbindin 1 concentrations with neurological outcomes in patients resuscitated from out-of-hospital cardiac arrest: a proteomics based pilot study. Bull Yamaguchi Med Sch. 2014. 61. 3-4. 23-35
Yasutaka Oda, Ryosuke Tsuruta, Motoki Fujita, Kotaro Kaneda, Yoshikatsu Kawamura, Tomonori Izumi, Shunji Kasaoka, Ikuro Maruyama, Tsuyoshi Maekawa. Prediction of the neurological outcome with intrathecal high mobility group box 1 and S100B in cardiac arrest victims: A pilot study. RESUSCITATION. 2012. 83. 8. 1006-1012
Aya Fujioka, Takashi Fujioka, Ryosuke Tsuruta, Tomonori Izumi, Shunji Kasaoka, Tsuyoshi Maekawa. Effects of a constant light environment on hippocampal neurogenesis and memory in mice. NEUROSCIENCE LETTERS. 2011. 488. 1. 41-44
Yasutaka Koga, Motoki Fujita, Ryosuke Tsuruta, Yoichi Koda, Takashi Nakahara, Takeshi Yagi, Tetsuya Aoki, Chihiro Kobayashi, Tomonori Izumi, Shunji Kasaoka, et al. Urinary trypsin inhibitor suppresses excessive superoxide anion radical generation in blood, oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion rats. NEUROLOGICAL RESEARCH. 2010. 32. 9. 925-932

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MISC (6)：

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Books (2)：

実験医学別冊タンパク質実験ハンドブック
羊土社 2003
Manual of Genetic Diseases
Nakayama-Shoten Co., Ltd. 1995

Lectures and oral presentations (45)：

血管内イベントにおける漏出細胞内タンパク質の役割
(第94回日本生化学会大会 2021)
プロテオーム解析技術の基礎と活用例
(平成29年度大学連携研究設備ネットワーク加速事業プロテオーム解析技術講習会 2017)
エイズ侵入タンパク質を用いた乳がん発症因子のハイスループットスクリーニング
(山口大学生命医工学センターシンポジウム 2014)
損傷細胞から放出されヒト単球細胞株U937細胞表面と相互作用する細胞内タンパク質のプロテオーム解析
(第86回日本生化学会総会 2013)
Selective analysis of cell surface-associated proteins: characterization of intracellular proteins that are released from damaged cells and interact with the surface of human monocytic cell line U937.
(第12回ヒトプロテオーム国際会議 2013)

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Professional career (3)：

博士(理学) (東京都立大学大学院)
理学修士 (東京都立大学大学院)
理学士 (東京都立大学)

Awards (2)：

1993 - International Symposium on High Performance Capillary Electrophoresis Student Travel Grants
1993 - クロマトグラフィー科学会第4回クロマトグラフィー科学会奨励賞グルコマンナンを利用したキャピラリー電気泳動によるオリゴヌクレオチドおよびDNAフラグメントの分離

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