Rchr
J-GLOBAL ID:201101078950126510
Update date: Feb. 01, 2024
Yamanaka Tomoyuki
ヤマナカ トモユキ | Yamanaka Tomoyuki
Affiliation and department:
Homepage URL (1):
https://nrid.nii.ac.jp/ja/nrid/1000000381575/
Research field (2):
Neuroanatomy and physiology
, Neuroscience - general
Research keywords (9):
ハンチンチン
, 凝集体
, ポリグルタミン
, HSP70
, ハンチントン病
, 神経疾患
, NF-Y
, 神経変性
, 転写因子
Research theme for competitive and other funds (10):
- 2021 - 2024 Screening of a novel strain that suppresses neurodegeneration
- 2018 - 2022 Analysis of chromatin structure in degenerating neurons
- 2017 - 2020 Interactome analysis to understand the cause of variations in neurodegenerative diseases
- 2015 - 2019 Molecular analysis of a novel ER stress response in neurons
- 2010 - 2015 The development and analysis of selective neuronal pathology
- 2012 - 2014 転写因子NF-Yを介した新たな神経維持・変性機構の解明
- 2011 - 2012 Identification of novel transcription factors involved in neuronal maintenance and degeneration.
- 2009 - 2010 Functional analysis of NF-Y transcription factor in nervous system
- 2006 - 2007 ハンチンチン結合タンパク質のなかから同定した新規転写因子
- 2000 - 2002 mPAR-6・aPKC・ASIP3者複合体の哺乳類細胞極性制御における役割の解明
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Papers (41):
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Tomoyuki Yamanaka, Masaru Kurosawa, Aya Yoshida, Tomomi Shimogori, Akiko Hiyama, Sankar N. Maity, Nobutaka Hattori, Hideaki Matsui, Nobuyuki Nukina. The Transcription factor NF-YA is Crucial for Neural Progenitor Maintenance during Brain Development. Journal of Biological Chemistry. 2024. in press
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Kazuki Kodera, Ryuichi Hishida, Akiko Sakai, Hiromi Nyuzuki, Noriko Matsui, Tomoyuki Yamanaka, Akihiko Saitoh, Hideaki Matsui. GPATCH4 contributes to nucleolus morphology and its dysfunction impairs cell viability. Biochemical and biophysical research communications. 2023. 693. 149384-149384
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Tomoyuki Yamanaka, Hideaki Matsui. Modeling familial and sporadic Parkinson's disease in small fishes. Development, growth & differentiation. 2023
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Hideaki Matsui, Shinji Ito, Hideki Matsui, Junko Ito, Ramil Gabdulkhaev, Mika Hirose, Tomoyuki Yamanaka, Akihide Koyama, Taisuke Kato, Maiko Tanaka, et al. Phosphorylation of α-synuclein at T64 results in distinct oligomers and exerts toxicity in models of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 23. e2214652120
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Hongsun Park, Tomoyuki Yamanaka, Nobuyuki Nukina. Proteomic analysis of heat-stable proteins revealed an increased proportion of proteins with compositionally biased regions. Scientific reports. 2022. 12. 1. 4347-4347
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MISC (20):
Work history (11):
- 2021/05 - 現在 Niigata University Brain Research Institute Center for Bioresources
- 2015/04 - 2021/04 同志社大学脳科学研究科 認知記憶加齢部門 准教授
- 2013/04 - 2015/03 Juntendo University
- 2010/04 - 2015/03 RIKEN
- 2007/04 - 2010/03 RIKEN
- 2005/03 - 2007/03 RIKEN
- 2003/04 - 2005/02 横浜市立大学医学部 分子細胞生物学教室 博士研究員
- 2002/04 - 2003/03 横浜市立大学医学部 分子細胞生物学教室 学術振興会特別研究員(PD)
- 2002/03 - 横浜市立大学 医学研究科 修了 博士(医学)の学位取得
- 1999/03 - Tokyo University of Science Graduate School of Pharmaceutical Sciences
- 1997/03 - Tokyo University of Science Faculty of Pharmaceutical Sciences, Department of Pharmacy
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